Energy

Fitness & Performance

Boosting vitality and reducing fatigue; important for daily productivity and quality of life.

Best effective

Caffeine
Other
Caffeine acts by blocking adenosine, a neurotransmitter that promotes relaxation and sleepiness. This leads to increased neural activity and a perceived boost in energy levels. Studies have consistently demonstrated caffeine's effectiveness in improving physical and mental performance, particularly in situations requiring sustained attention and wakefulness.
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Coenzyme Q10
Other
CoQ10 is a crucial component of the electron transport chain, responsible for generating ATP, the primary energy currency of cells. Supplementation can improve mitochondrial function and ATP production, resulting in increased energy levels. This effect is particularly pronounced in individuals with conditions like mitochondrial disorders, statin-induced myopathy, or age-related decline in CoQ10 levels.
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Eleuthero
Botanical
Studies suggest that Eleuthero can improve physical stamina and reduce fatigue. Its adaptogenic properties help the body cope with stress, which often manifests as low energy levels. Users report experiencing increased alertness and endurance with regular supplementation.
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Guarana
Botanical
Guarana's caffeine is released more slowly than coffee, which provides prolonged energy without a quick crash. This makes it a popular choice for boosting energy in a sustained manner. Studies show that guarana is an effective energizer.
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Iron
Mineral
Iron is a key component of hemoglobin, the protein in red blood cells that carries oxygen. When iron levels are low, the body can't produce enough hemoglobin, leading to reduced oxygen delivery to tissues and organs. This lack of oxygen can result in fatigue, weakness, and reduced energy levels. Supplementing iron can help restore healthy hemoglobin levels and improve overall energy.
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Riboflavin
Vitamin
Riboflavin, also known as vitamin B2, is a crucial component of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are coenzymes vital to many metabolic reactions. These reactions are central to energy production, particularly in the citric acid cycle and electron transport chain. A deficiency in riboflavin can lead to decreased energy production and fatigue. Supplementing riboflavin can help ensure these pathways function optimally, leading to improved energy levels.
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Thiamin
Vitamin
Thiamin plays a vital role in the Krebs cycle, a key part of cellular respiration, where energy is generated. Without sufficient thiamin, the body's ability to produce energy from food is impaired, resulting in fatigue. Numerous studies confirm this.
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Vitamin B12
Vitamin
B12 is a key component in converting carbohydrates into glucose, which the body uses for energy. Insufficient B12 can lead to fatigue and lethargy. Many people report noticing increased energy levels after supplementing with B12, especially those with deficiencies.
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Very effective

Acetyl L-Carnitine
Other
By assisting in the transport of fatty acids into the mitochondria, ALCAR can enhance the body's ability to use fat for fuel, potentially leading to increased energy levels. This effect is more pronounced when the body is under stress or energy demands are high.
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Blue-Green Algae
Botanical
The high content of B vitamins, especially B12, along with iron and readily available protein, makes blue-green algae a good supplement for those seeking an energy boost. B vitamins are crucial for energy production at the cellular level, and iron is vital for oxygen transport. The protein provides building blocks for repair and further energy.
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Coenzyme Q-10
Other
CoQ10 is an essential component of the electron transport chain, which is responsible for generating ATP, the primary energy currency of the cell. Supplementation can enhance mitochondrial function and ATP production, leading to increased energy levels and reduced fatigue.
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Cordyceps
Botanical
Studies show that cordyceps can enhance physical endurance by increasing oxygen uptake and reducing lactic acid build-up during exercise, leading to improved energy levels and reduced fatigue. This is due to it's effect on improving ATP production
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Magnesium
Mineral
Magnesium is a cofactor for enzymes involved in the creation of ATP, the primary energy currency of cells. Deficiency can lead to fatigue and reduced energy levels, hence magnesium supplementation can be effective for increased energy.
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Phosphorus
Mineral
ATP (adenosine triphosphate) production, fundamental for energy generation in cells, is directly dependent on phosphate groups derived from phosphorus.
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Rhodiola
Botanical
Studies suggest that Rhodiola can combat fatigue and enhance mental performance, contributing to increased energy.
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Theobromine
Other
Theobromine acts as a phosphodiesterase inhibitor, increasing cAMP levels and promoting alertness and energy. It also stimulates the cardiovascular system, increasing blood flow and oxygen delivery to the brain and muscles, contributing to a feeling of increased energy and reduced fatigue.
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Vitamin B6
Vitamin
Vitamin B6 is a cofactor for enzymes involved in gluconeogenesis (glucose production from non-carbohydrate sources), glycogenolysis (breakdown of glycogen to release glucose), and amino acid metabolism. These processes are essential for maintaining energy levels.
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Decently effective

Acetyl-L-Carnitine
Other
By facilitating the transport of fatty acids into mitochondria, ALCAR can increase ATP production, the primary energy currency of cells. This may result in improved energy levels and reduced fatigue, especially in individuals with impaired mitochondrial function.
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Ashwagandha
Botanical
Ashwagandha can improve energy levels by combating fatigue related to chronic stress and improving overall vigor.
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Aspartic Acid
Amino Acid
Through its role in the urea cycle, aspartic acid aids in the clearance of ammonia, which can cause fatigue. By reducing ammonia buildup, it helps improve energy levels. Some people report feeling more energetic after supplementing.
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Astragalus
Botanical
Astragalus's potential to improve circulation and reduce fatigue can contribute to improved energy levels. The effects may vary among individuals.
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Creatine
Other
While creatine doesn't directly provide sustained energy like carbohydrates or fats, it plays a critical role in rapidly replenishing ATP stores during high-intensity activities, leading to enhanced power output and reduced fatigue. It supports energy metabolism during exercise.
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Isoleucine
Amino Acid
While not the primary energy source like carbohydrates, isoleucine can be converted into glucose to provide energy when needed. It's especially relevant during prolonged exercise sessions when glycogen stores may become low. Supplementing with isoleucine can help maintain energy levels.
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Niacin
Vitamin
Niacin plays a crucial role in the conversion of food into energy at the cellular level, supporting overall metabolic function and energy levels.
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Valine
Amino Acid
Valine can be used by the body as an energy source when glucose levels are low, especially during prolonged exercise. While not a primary energy provider, it plays a supportive role in maintaining energy levels.
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Vitamin B5
Vitamin
Vitamin B5, as a component of Coenzyme A, is essential for the Krebs cycle, a key metabolic pathway that generates energy in cells. It plays a vital role in converting food into usable energy. Deficiencies can therefore impair energy metabolism.
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Partially effective

Alanine
Amino Acid
Alanine can be converted to glucose in the liver, a process known as gluconeogenesis. This is helpful during periods of fasting or prolonged exercise when glycogen stores are depleted, therefore providing a source of energy.
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Chromium
Mineral
Improved insulin sensitivity can help the body use glucose more effectively as fuel, leading to fewer energy fluctuations throughout the day.
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Octacosanol
Other
Anecdotal evidence and some research indicate that octacosanol could potentially increase energy levels and decrease fatigue by influencing lipid metabolism. However, further investigation is needed.
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Potassium
Mineral
Potassium is involved in maintaining fluid and electrolyte balance, which is crucial for energy production. It supports the proper functioning of cells, ensuring efficient metabolic processes. Low potassium can lead to fatigue.
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Situationally effective

Tribulus
Botanical
Users have reported feeling a mild boost in energy, which may be linked to hormonal regulation. However, this effect isn't consistent for everyone and may only be noticeable in those with energy deficiencies.
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