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Senolytic Activator

Life Extension
4.6
(4126 ratings)
Apigenin 50 mg
Product Image
Score 72.0

The Senolytic Activator from Life Extension combines Apigenin, highly bioavailable Bio-Quercetin, and Theaflavins, providing a synergistic formula that supports sleep, stress relief, and brain health through its calming and antioxidant properties.

Quantity: 24 Capsule(s)Servings size: 2 Vegetarian Capsule(s) (12 servings)
Selected goals:
Other goals:
Immunity
Heart Health
Anti-Aging
Joint Health
Sleep Support

Score 72.0

The Senolytic Activator from Life Extension combines Apigenin, highly bioavailable Bio-Quercetin, and Theaflavins, providing a synergistic formula that supports sleep, stress relief, and brain health through its calming and antioxidant properties.

Analysis

Life Extension's Senolytic Activator features a potent combination of 50mg Apigenin, 74mg Bio-Quercetin Phytosome, and 275mg Theaflavins from decaffeinated black tea extract. While the product is named for its senolytic (cellular aging) properties, its ingredient profile directly aligns with the stated goals of Sleep Support, Stress Relief, and Brain Health. Apigenin is a well-researched flavonoid known for its anxiolytic effects and ability to promote relaxation by interacting with GABA receptors, making it beneficial for both sleep and stress. Bio-Quercetin Phytosome ensures superior absorption of quercetin, a powerful antioxidant and anti-inflammatory agent, which supports overall cellular health, including brain function. Theaflavins further contribute with antioxidant properties, potentially aiding cognitive function and reducing oxidative stress.

Pros
  • Contains Apigenin, a key ingredient for promoting relaxation and aiding sleep, at a clinically relevant dose.
  • Includes Bio-Quercetin Phytosome, which significantly enhances the bioavailability of quercetin, maximizing its antioxidant and anti-inflammatory benefits for brain health.
  • Features Theaflavins from black tea extract, offering additional antioxidant support that contributes to overall cellular and brain health.
  • Formulated by Life Extension, a reputable brand known for its science-backed supplements and quality control.
  • High review count indicates general positive user experience and product efficacy for many consumers.
Cons
  • The price per serving is relatively high compared to single-ingredient Apigenin supplements, which may be a barrier for budget-conscious consumers focused solely on Apigenin's effects.
  • The product's primary marketing as a 'Senolytic Activator' might overshadow its direct benefits for sleep, stress, and brain health, potentially confusing consumers seeking specific support in those areas.
  • With only 12 servings per bottle, it requires frequent repurchase, which can be less convenient for long-term use.
Warnings
  • Individuals taking blood-thinning medications should consult a healthcare professional before use, as quercetin may have mild anti-platelet effects.
  • As with any supplement, it is advisable to consult a healthcare provider before use, especially if you have pre-existing medical conditions or are taking other medications.
$16.49($1.37 per serving)
Amazon
$ 16.49
Walmart
$ 16.49
iHerb
$ 19.50
Ingredients
IngredientAmount per serving
Theaflavins (decaffeinated Black Tea extract) 275 mg
Bio-Quercetin Phytosome 74 mg
Apigenin 50 mg
Gluten Free Adults 18–50
Categories
Apigenin 75.0
The product provides a good 50mg dose of Apigenin, which is consistent with effective dosages found in research and commonly recommended by nutritionists for various benefits, including sleep and relaxation. Its inclusion alongside Bio-Quercetin Phytosome offers a synergistic effect beyond a standalone Apigenin supplement.
Goals
Sleep Support 75.0
Apigenin is the most impactful ingredient for sleep support in this formula, effectively promoting relaxation and reducing the time it takes to fall asleep by interacting with brain receptors. The 50mg dose is well-regarded by nutritionists and online reviews for its calming effects without inducing heavy sedation.
Stress Relief 70.0
Apigenin plays a crucial role in stress reduction due to its anxiolytic properties, helping to calm the nervous system and promote a sense of well-being. While other ingredients offer general health benefits, Apigenin is the direct contributor to immediate stress relief.
Brain Health 70.0
The Bio-Quercetin Phytosome and Theaflavins are powerful antioxidants and anti-inflammatory compounds that support brain health by protecting neurons from oxidative damage and inflammation. Apigenin also contributes through its neuroprotective effects and potential to modulate neural pathways, offering holistic brain support.
90 Value

Two-Per-Day Capsules

Life Extension
4.7
(85932 ratings)
At $0.15 per serving, it offers an incredibly comprehensive multivitamin with 5mg Apigenin and 15mg Bio-Quercetin Phytosome, along with numerous other beneficial compounds. This delivers exceptional value for a wide range of health benefits, including those related to the stated goals, far surpassing the original product's limited scope at a high price.
88 Value

Two-Per-Day Tablets

Life Extension
4.8
(56222 ratings)
Providing excellent nutritional coverage including Apigenin and Bio-Quercetin Phytosome at $0.30 per serving, this multivitamin offers a significantly better overall health investment compared to the highly specialized and expensive Senolytic Activator. Its broad nutrient profile supports general wellness, which underpins brain health, stress resilience, and quality sleep.
80 Value

Daily Multivitamins

California Gold Nutrition
4.7
(11651 ratings)
This multivitamin includes 5mg Apigenin and 15mg Bio-Quercetin Phytosome, along with a good array of vitamins and minerals, for a reasonable $0.58 per serving. It provides a more holistic approach to health support for sleep, stress, and brain function, offering good value compared to the niche Senolytic Activator.
95 Performance

Life Extension Mix Powder

Life Extension
4.3
(389 ratings)
While a general multivitamin powder with only 5mg Apigenin, its robust blend of numerous vitamins, minerals, antioxidants, and adaptogens (like Ashwagandha) provides superior overall support for brain health, stress resilience, and indirectly, sleep, offering a more holistic approach.
90 Performance

Two-Per-Day Capsules

Life Extension
4.7
(85932 ratings)
This is a high-potency daily multivitamin that includes 5mg Apigenin, 15mg Bio-Quercetin Phytosome, and a broad spectrum of vitamins, minerals, and other compounds crucial for overall health, energy, and brain function, making it a more comprehensive and potentially more impactful choice for the stated goals.
90 Performance

Two-Per-Day Tablets

Life Extension
4.8
(56222 ratings)
Similar to the Two-Per-Day Capsules, this tablet form offers a very comprehensive array of nutrients including 5mg Apigenin and 15mg Bio-Quercetin Phytosome. Its broad spectrum of vitamins and minerals provides superior foundational support for brain health, stress response, and general well-being than a specific senolytic blend.
95 Budget

Apigenin 50 mg

Swanson
4.5
(2688 ratings)
This alternative offers the exact same 50mg Apigenin dose at a significantly lower price per serving ($0.17 vs $1.37), making it a far more cost-effective option for targeting the primary Apigenin-related benefits of sleep and stress relief.
80 Budget

Apigenin

Codeage
4.6
(1301 ratings)
This product provides the core 50mg Apigenin at a much lower price per serving ($0.33 vs $1.37). It offers similar direct benefits for sleep and stress without the added cost of the other ingredients found in the Senolytic Activator.
78 Budget

NMN Flavonoid Complex

California Gold Nutrition
4.6
(5436 ratings)
Although it contains 25mg of Apigenin (half the dose), it's considerably cheaper per serving ($0.28 vs $1.37) and includes NMN and Dihydroquercetin, offering a different set of potential cellular and brain health benefits at a better price point.
90 Value

Two-Per-Day Capsules

Life Extension
4.7
(85932 ratings)
At $0.15 per serving, it offers an incredibly comprehensive multivitamin with 5mg Apigenin and 15mg Bio-Quercetin Phytosome, along with numerous other beneficial compounds. This delivers exceptional value for a wide range of health benefits, including those related to the stated goals, far surpassing the original product's limited scope at a high price.
88 Value

Two-Per-Day Tablets

Life Extension
4.8
(56222 ratings)
Providing excellent nutritional coverage including Apigenin and Bio-Quercetin Phytosome at $0.30 per serving, this multivitamin offers a significantly better overall health investment compared to the highly specialized and expensive Senolytic Activator. Its broad nutrient profile supports general wellness, which underpins brain health, stress resilience, and quality sleep.
80 Value

Daily Multivitamins

California Gold Nutrition
4.7
(11651 ratings)
This multivitamin includes 5mg Apigenin and 15mg Bio-Quercetin Phytosome, along with a good array of vitamins and minerals, for a reasonable $0.58 per serving. It provides a more holistic approach to health support for sleep, stress, and brain function, offering good value compared to the niche Senolytic Activator.
95 Performance

Life Extension Mix Powder

Life Extension
4.3
(389 ratings)
While a general multivitamin powder with only 5mg Apigenin, its robust blend of numerous vitamins, minerals, antioxidants, and adaptogens (like Ashwagandha) provides superior overall support for brain health, stress resilience, and indirectly, sleep, offering a more holistic approach.
90 Performance

Two-Per-Day Capsules

Life Extension
4.7
(85932 ratings)
This is a high-potency daily multivitamin that includes 5mg Apigenin, 15mg Bio-Quercetin Phytosome, and a broad spectrum of vitamins, minerals, and other compounds crucial for overall health, energy, and brain function, making it a more comprehensive and potentially more impactful choice for the stated goals.
90 Performance

Two-Per-Day Tablets

Life Extension
4.8
(56222 ratings)
Similar to the Two-Per-Day Capsules, this tablet form offers a very comprehensive array of nutrients including 5mg Apigenin and 15mg Bio-Quercetin Phytosome. Its broad spectrum of vitamins and minerals provides superior foundational support for brain health, stress response, and general well-being than a specific senolytic blend.