Mega-Size BCAA 1000 Caps
Optimum Nutrition
Mega-Size BCAA 1000 Caps
4.6
★ ★ ★ ★ ★
(25137 ratings)
Valine 250 mg
Isoleucine 250 mg
Leucine 500 mg
Score 70.0
A popular and affordable BCAA capsule supplement from Optimum Nutrition, providing 1 gram per serving, which is convenient but a low dose for optimal muscle-building effects compared to many powder alternatives or complete proteins.
Quantity: 200 Capsule(s)Servings size: 2 Capsule(s) (100 servings)
Selected goals:
Other goals:
Fitness
Muscle Gain
Energy
Weight Gain
leaderboard Score 70.0
A popular and affordable BCAA capsule supplement from Optimum Nutrition, providing 1 gram per serving, which is convenient but a low dose for optimal muscle-building effects compared to many powder alternatives or complete proteins.
insights Analysis
Optimum Nutrition's Mega-Size BCAA 1000 Caps provide 1 gram of Branched-Chain Amino Acids per serving in a 2:1:1 ratio (500mg Leucine, 250mg Isoleucine, 250mg Valine). While BCAAs are crucial for muscle protein synthesis, especially Leucine, the 1-gram dosage per serving is relatively low compared to clinical studies often suggesting 5-10 grams, or compared to the BCAA content in a standard protein shake. Nutritionists often emphasize that a complete protein source is more effective for muscle growth than BCAAs alone, as all essential amino acids are required for optimal protein synthesis. However, for those seeking a convenient BCAA supplement in capsule form, particularly for intra-workout or specific timing, this product from a highly reputable brand with a massive positive review count offers a cost-effective option per gram of BCAA, though higher doses would require multiple capsules. Compared to alternatives like XTEND that offer 7g of BCAAs plus other beneficial ingredients per serving, or even a basic whey protein isolate, this product serves a more niche purpose for lower-dose BCAA supplementation.
- Reputable and well-regarded brand (Optimum Nutrition).
- High review count indicates widespread popularity and user satisfaction.
- Convenient capsule form for easy consumption.
- Good price per serving for 1g of BCAA.
- Micronized ingredients for potentially better absorption.
- Low dosage of BCAAs per serving (1g), requiring multiple capsules for higher, more effective doses.
- BCAAs alone are generally less effective for muscle protein synthesis than a complete protein or EAA supplement due to the lack of other essential amino acids.
- Not a substitute for a complete protein source in the diet; amino acid supplements should complement, not replace, whole food protein intake.
- Individuals with specific health conditions or pregnant/nursing women should consult a healthcare professional before use to ensure suitability.
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bolt Effectiveness for goals
Branched-chain amino acids, including Leucine, Isoleucine, and Valine, are involved in the process of muscle protein synthesis, essential for repairing and rebuilding muscle tissue. They can help mitigate exercise-induced muscle damage and reduce muscle soreness. This supports quicker recovery post-workout.
L-Leucine is often considered the most crucial BCAA for stimulating muscle protein synthesis. It directly activates the mTOR pathway, which is a key regulator of cell growth and protein production. This makes it vital for muscle building and repair processes.
Research suggests that supplementing with branched-chain amino acids may help alleviate delayed onset muscle soreness (DOMS) following strenuous physical activity. This effect is thought to be due to their role in reducing muscle damage and supporting reparative processes. They contribute to a quicker return to normal muscle function.
While branched-chain amino acids can be consumed at various times, many individuals prefer taking them around their workouts. Pre- or intra-workout intake may help reduce muscle breakdown, while post-workout consumption can further support recovery and muscle protein synthesis. The timing can depend on individual goals and training regimens.
The 2:1:1 ratio, which provides twice the amount of Leucine compared to Isoleucine and Valine, is a common formulation in BCAA supplements. This ratio emphasizes Leucine's primary role in activating muscle protein synthesis. Isoleucine and Valine also contribute to muscle repair and energy metabolism, making it a balanced approach.
schedule Dosage, timing & forms
BCAAs are often consumed around workout times, either before, during, or immediately after exercise, to support muscle recovery and reduce fatigue. Some individuals also take them between meals to maintain amino acid levels. The timing can depend on individual training goals and dietary protein intake.
A typical daily intake for BCAAs in supplement form can range from 5-10 grams, often split into multiple doses throughout the day. The specific amount may vary based on an individual's body weight, activity level, and overall dietary protein consumption. Always adhere to product-specific serving suggestions.
While both forms effectively deliver branched-chain amino acids, powders mixed in liquid may be absorbed slightly faster due to their pre-dissolved state. Capsules provide convenience and precise dosing but require the capsule material to dissolve first in the digestive system. The overall bioavailability is generally comparable.
The 2:1:1 ratio emphasizes Leucine, which is a key amino acid known to strongly stimulate muscle protein synthesis. While Isoleucine and Valine also play important roles in muscle metabolism and energy, this specific ratio is designed to maximize the anabolic signaling for muscle growth and recovery.
Taking BCAAs on an empty stomach may lead to faster absorption and quicker availability to muscles. However, they can also be effectively consumed with meals, though absorption might be slightly slower. The choice depends on personal preference and how quickly you want the amino acids to enter your system.
health_and_safety Safety & interactions
BCAA supplements are generally well-tolerated when taken at recommended doses. Possible mild side effects, though rare, may include stomach upset, nausea, or diarrhea in some individuals. If you experience adverse reactions, discontinue use and consult a healthcare professional.
BCAAs may potentially interact with certain medications, such as those for diabetes, as they can affect blood sugar levels. They might also interfere with medications for Parkinson's disease or thyroid hormones. It's advisable to consult a healthcare professional before use if you are on any prescribed medication.
Individuals with pre-existing kidney or liver conditions should exercise caution and consult a healthcare professional before taking BCAA supplements. While BCAAs are metabolized by the liver, excessive intake might place additional strain on these organs. A medical evaluation can determine suitability.
Yes, some research suggests that BCAAs, particularly leucine, can influence insulin signaling and blood glucose regulation. They may potentially lower blood sugar levels in some individuals. People with diabetes or those managing blood sugar should monitor their levels carefully.
Individuals with Maple Syrup Urine Disease (MSUD), a genetic disorder affecting BCAA metabolism, must avoid BCAA supplements. Also, caution is advised for pregnant or breastfeeding women, and those with chronic kidney or liver disease. Always consult a healthcare provider for personalized advice.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| L-Leucine, Micronized | 500 mg |
| L-Isoleucine, Micronized | 250 mg |
| L-Valine, Micronized | 250 mg |
Categories
Leucine 70.0
The product contains 500mg of Leucine per serving, which is the key amino acid for initiating muscle protein synthesis. While it's present, higher doses (e.g., 2-3g per serving) are often recommended for optimal anabolic signaling, typically found in a full protein meal or higher-dose BCAA supplements.
Valine 70.0
Valine is one of the three BCAAs and is present at 250mg per serving, contributing to the standard 2:1:1 ratio. It plays a role in energy production and muscle metabolism, working synergistically with Leucine and Isoleucine, supporting muscle maintenance during intense exercise.
Isoleucine 70.0
Isoleucine is included at 250mg per serving, balancing the BCAA profile. It is involved in glucose uptake and utilization in muscle tissue, offering benefits for energy and recovery during exercise, and helps regulate blood sugar levels, which is beneficial during physical activity.
Goals
Fitness 75.0
BCAAs can contribute to reduced muscle soreness, improved recovery, and potentially decreased exercise-induced muscle damage, supporting overall fitness and consistent training. The convenience of capsules makes it easy to integrate into a fitness routine, aiding workout consistency and performance over time.
Muscle Gain 65.0
While BCAAs, particularly Leucine, initiate muscle protein synthesis, a single gram per serving is a suboptimal dose for significant muscle gain, as most research suggests 5-10 grams post-workout or during training. Furthermore, complete protein sources containing all essential amino acids are generally superior for maximal muscle growth and repair.
Energy 60.0
BCAAs can be utilized as an energy source during prolonged exercise and may help reduce central fatigue by competing with tryptophan for brain entry, potentially making workouts feel less taxing. However, they are not a primary, fast-acting energy source like carbohydrates, and their direct energy contribution is secondary.