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Circadian Sleep

Life Extension
4.5
(207 ratings)
Melatonin 1.5 mg
Product Image
Score 90.0

Premium, sustained-release melatonin with Nobiletin for comprehensive circadian and sleep cycle support, justifying its higher price point.

Quantity: 30 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Stress Relief
Anti-Aging
Sleep Support

Score 90.0

Premium, sustained-release melatonin with Nobiletin for comprehensive circadian and sleep cycle support, justifying its higher price point.

Analysis

Life Extension's Circadian Sleep is an intelligently formulated supplement designed to support the full sleep cycle. Its key ingredient, 1.5mg of MicroActive Melatonin, is a sustained-release form that aims to mimic the body's natural melatonin production, helping users stay asleep throughout the night without next-day grogginess. The addition of 50mg Nobiletin, a citrus flavonoid, is noteworthy for its potential role in regulating circadian rhythms. This product moves beyond simple melatonin supplementation by addressing sleep maintenance and biological clock regulation, making it a favorite among nutritionists for its thoughtful design. Online reviews often highlight improved sleep quality and reduced morning fatigue.

Pros
  • MicroActive Melatonin provides sustained release, aiding sleep maintenance.
  • Nobiletin supports circadian rhythm regulation for healthier sleep patterns.
  • Physiologically appropriate 1.5mg melatonin dose reduces risk of next-day grogginess.
  • Comprehensive approach to sleep health beyond just sleep onset.
Cons
  • Higher price per serving compared to standard melatonin products.
Warnings
  • As with any sleep aid, individual responses may vary, and it's important to establish a consistent sleep routine alongside supplementation.
  • Consult a healthcare professional if you experience persistent sleep issues or are taking other medications, as Nobiletin could potentially interact with certain drugs.
$21.00($0.70 per serving)
Pure Formulas
$ 21.00
iHerb
$ 21.00
Ingredients
IngredientAmount per serving
Nobiletin (Citrus fruit) 50 mg
MicroActive Melatonin (Melatonin) 1.5 mg
Adults 18–50
Categories
Melatonin 90.0
This product represents an advanced iteration of melatonin supplementation, moving beyond a simple dose to offer a sophisticated sustained-release mechanism. Its combination with Nobiletin specifically targets the broader aspects of circadian rhythm and sleep quality, setting a high standard for effectiveness within the melatonin category.
Goals
Sleep Support 95.0
The sustained-release MicroActive Melatonin is highly effective for both sleep onset and, critically, for maintaining sleep throughout the night, addressing a common complaint with immediate-release melatonin. This intelligent delivery system ensures that melatonin levels remain elevated, promoting consistent, natural-feeling sleep cycles without the sudden peak and drop that can cause awakenings.
Stress Relief 85.0
By fostering stable and restorative sleep through sustained melatonin release and circadian rhythm regulation, this product significantly contributes to improved stress resilience. A well-regulated sleep-wake cycle reduces the physiological burden of sleep deprivation, which is a major contributor to stress, leading to a more balanced emotional state.
Anti-Aging 80.0
Melatonin's powerful antioxidant properties, especially when delivered in a sustained manner, can help protect cells from oxidative damage, which is a key factor in the aging process. Nobiletin also has antioxidant and potential cellular health benefits, further contributing to the product's anti-aging potential by supporting overall cellular function and repair during sleep.
88 Value

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Melatonin 3 mg

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(4544 ratings)
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(2630 ratings)
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Ortho Sleep

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(128 ratings)
A unique blend combining Melatonin (6mg) with a Multi-Collagen Complex and Magnesium, offering not only sleep support but also potential beauty and relaxation benefits from a premium brand.