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Detox & Liver Health

Reg'Activ
4.7
(170 ratings)
Methionine
Milk Thistle 250 mg
Selenium 100 mcg
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Score 65.0

A liver support supplement with Milk Thistle, NAC, L-Methionine, and a unique probiotic for detoxification. Offers good ingredient synergy but with moderate dosages at a higher price point compared to many alternatives.

Quantity: 60 Capsule(s)Servings size: 2 Capsule(s) (30 servings)
Selected goals:
Other goals:
Immunity
Detoxification
Skin Health
Brain Health
Hair Health

Score 65.0

A liver support supplement with Milk Thistle, NAC, L-Methionine, and a unique probiotic for detoxification. Offers good ingredient synergy but with moderate dosages at a higher price point compared to many alternatives.

Analysis

Reg'Activ Detox & Liver Health is formulated with a combination of ingredients aimed at supporting liver function and general detoxification pathways. Key components include Milk Thistle, known for its hepatoprotective properties, N-Acetyl-Cysteine (NAC) as a glutathione precursor, and L-Methionine, an amino acid involved in methylation and sulfur metabolism essential for detox. A distinguishing feature is the inclusion of Lactobacillus fermentum ME-3, a probiotic strain with documented antioxidant and glutathione-producing capabilities, which adds a unique dimension to its detoxification claims. The product also contains Selenium in the well-absorbed selenomethionine form, further enhancing its antioxidant profile and immune support. While the ingredient choices are sound for the stated goals, the potency of some key ingredients like L-Methionine (50mg) and NAC (200mg) is on the lower end compared to doses often recommended for more intensive liver support, or found in more cost-effective alternatives. The price per serving of $1.33 is relatively high, especially when considering alternative products that offer higher dosages or a broader spectrum of liver-supporting compounds at a more competitive price point.

Pros
  • Contains a synergistic blend of ingredients targeting liver health and detoxification.
  • Includes Lactobacillus fermentum ME-3, a unique probiotic strain that contributes to glutathione production and antioxidant activity.
  • Utilizes Selenomethionine, a highly bioavailable form of Selenium.
  • Provides essential amino acids and herbal extracts known for their roles in detoxification pathways.
Cons
  • Dosages of L-Methionine (50mg) and N-Acetyl-Cysteine (200mg) are relatively low for significant therapeutic impact compared to some other formulations.
  • The price per serving ($1.33) is on the higher side, especially when benchmarked against other multi-ingredient liver support supplements or single-ingredient alternatives.
  • Claims for 'Skin Health', 'Hair Health', and 'Nail Health' are less directly supported by the ingredient profile compared to specialized products for these specific goals.
Warnings
  • Individuals with allergies to any ingredients, especially milk thistle, should exercise caution.
  • Pregnant or nursing women, individuals on medication, or those with pre-existing medical conditions should consult a healthcare professional before using this product.
$39.96($1.33 per serving)
Pure Formulas
$ 39.96
iHerb
$ 40.00
Vitacost
$ 49.95
Ingredients
IngredientAmount per serving
Selenium (Selenomethionine) 100 mcg
Lactobacillus fermentum ME-3 60 mg
Milk Thistle fruit extract 250 mg
N-Acetyl-Cysteine 200 mg
L-Methionine 50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Categories
Selenium 75.0
The product contains 100mcg of Selenium in the Selenomethionine form, which is highly bioavailable and provides effective antioxidant and thyroid support, aligning well with general health and immunity goals.
Milk Thistle 70.0
The 250mg of Milk Thistle fruit extract is a good foundational dose for liver support. While it's effective, the lack of specified standardization to silymarin and the availability of alternatives offering higher standardized doses for a lower price slightly impacts its score.
Methionine 60.0
The inclusion of 50mg of L-Methionine is beneficial for liver detoxification and methylation pathways. However, this dosage is comparatively low when stacked against dedicated methionine supplements or comprehensive liver formulas that often provide 200-500mg per serving.
Goals
Immunity 75.0
Selenium and N-Acetyl-Cysteine (NAC) are both vital for immune function due to their antioxidant properties and roles in glutathione synthesis. The unique probiotic strain, Lactobacillus fermentum ME-3, also supports immune health by enhancing the body's antioxidant defenses.
General Health 70.0
The combination of liver-supporting ingredients like Milk Thistle, antioxidants like NAC and Selenium, and the probiotic for gut health contributes to overall well-being by aiding the body's natural processes and reducing oxidative stress.
Detoxification 70.0
Milk Thistle, N-Acetyl-Cysteine (NAC) as a glutathione precursor, and L-Methionine are well-recognized for their roles in supporting the liver's natural detoxification processes. The addition of Lactobacillus fermentum ME-3 further enhances detox capabilities through its glutathione-producing action.
98 Value

Selenium 200 mcg

NOW
4.8
(26270 ratings)
This product offers double the selenium dose (200mcg L-Selenomethionine, a highly bioavailable form) at an exceptionally low price per serving ($5 vs $133), providing outstanding value for robust selenium supplementation.
95 Value

Silymarin Complex

California Gold Nutrition
4.8
(70295 ratings)
Delivering 300mg of standardized Milk Thistle (Silymarin), which is superior in quality and quantity to the original's unstandardized 250mg, this alternative is available at a remarkable price per serving ($8 vs $133), offering excellent value for comprehensive liver support.
80 Value

Advanced Liver Support

Super Nutrition
4.8
(1639 ratings)
This alternative provides a higher dose of Milk Thistle (300mg) and includes L-Methionine (20mg), offering a solid combination for liver and detoxification support at a significantly more affordable price per serving ($26 vs $133).
85 Performance

Puri-T

LifeSeasons
4.7
(294 ratings)
This product offers a combination of Selenium (250mcg Selenomethionine, higher dose) and Milk Thistle (225mg standardized Silymarin), providing superior forms and potencies for two key ingredients compared to the original, at a comparable per-serving price ($99 vs $133).
88 Performance

Liver Refresh

NOW
4.8
(19787 ratings)
Specifically formulated for liver support, this alternative contains a higher and standardized dose of Milk Thistle (300mg Silymarin Flavonoids) along with L-Methionine, offering a more effective solution for detoxification at a much lower price per serving ($39 vs $133).
90 Performance

Double Strength Silymarin 300 mg

NOW
4.8
(59188 ratings)
This alternative provides a significantly higher and standardized dosage of Milk Thistle (300mg Silymarin Flavonoids) than the original's unstandardized 250mg, at a vastly reduced price per serving ($14 vs $133), making it a much more potent and effective option for liver health.
95 Budget

Selenium 100 mcg

Swanson
4.8
(3370 ratings)
This alternative provides the exact same 100mcg dose of L-Selenomethionine as the original product, but at an incredibly lower price per serving ($2 vs $133), offering exceptional value if selenium is the primary desired benefit.
90 Budget

Milk Thistle 250 mg

Nature's Bounty
4.7
(6884 ratings)
For liver support, this alternative offers the same 250mg of Milk Thistle, crucially standardized to silymarin (which the original lacks), at a significantly cheaper price per serving ($8 vs $133), providing superior value for the key liver ingredient.
92 Budget

Pharmaceutical Grade AjiPure L-Methionine 500 mg

Swanson Ultra
4.7
(219 ratings)
This alternative delivers a substantially higher dose of L-Methionine (500mg compared to 50mg in the original) at a drastically lower price per serving ($15 vs $133), representing a much more cost-effective way to supplement methionine.
98 Value

Selenium 200 mcg

NOW
4.8
(26270 ratings)
This product offers double the selenium dose (200mcg L-Selenomethionine, a highly bioavailable form) at an exceptionally low price per serving ($5 vs $133), providing outstanding value for robust selenium supplementation.
95 Value

Silymarin Complex

California Gold Nutrition
4.8
(70295 ratings)
Delivering 300mg of standardized Milk Thistle (Silymarin), which is superior in quality and quantity to the original's unstandardized 250mg, this alternative is available at a remarkable price per serving ($8 vs $133), offering excellent value for comprehensive liver support.
80 Value

Advanced Liver Support

Super Nutrition
4.8
(1639 ratings)
This alternative provides a higher dose of Milk Thistle (300mg) and includes L-Methionine (20mg), offering a solid combination for liver and detoxification support at a significantly more affordable price per serving ($26 vs $133).
85 Performance

Puri-T

LifeSeasons
4.7
(294 ratings)
This product offers a combination of Selenium (250mcg Selenomethionine, higher dose) and Milk Thistle (225mg standardized Silymarin), providing superior forms and potencies for two key ingredients compared to the original, at a comparable per-serving price ($99 vs $133).
88 Performance

Liver Refresh

NOW
4.8
(19787 ratings)
Specifically formulated for liver support, this alternative contains a higher and standardized dose of Milk Thistle (300mg Silymarin Flavonoids) along with L-Methionine, offering a more effective solution for detoxification at a much lower price per serving ($39 vs $133).
90 Performance

Double Strength Silymarin 300 mg

NOW
4.8
(59188 ratings)
This alternative provides a significantly higher and standardized dosage of Milk Thistle (300mg Silymarin Flavonoids) than the original's unstandardized 250mg, at a vastly reduced price per serving ($14 vs $133), making it a much more potent and effective option for liver health.