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Active B12 with L-5-MTHF

Seeking Health
4.7
(3264 ratings)
Vitamin B12 1000 mcg
Product Image
Score 85.0

A high-quality B12 supplement using bioavailable forms, ideal for comprehensive methylation support, energy, and cognitive function, though at a premium price.

Quantity: 60 Liquid(s)Servings size: 1 Lozenge(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost

Score 85.0

A high-quality B12 supplement using bioavailable forms, ideal for comprehensive methylation support, energy, and cognitive function, though at a premium price.

Analysis

This product offers Vitamin B12 in its highly bioavailable Mecobalactive form (a branded Methylcobalamin), along with L-5-MTHF, an active form of folate. This combination is particularly effective for individuals seeking comprehensive methylation support, which is crucial for energy production, brain health, and mood regulation. The use of active forms ensures direct utilization by the body, bypassing the need for metabolic conversion, which can be inefficient for some people. Online reviews and nutritionist recommendations often favor active B12 and folate forms for their superior absorption and efficacy in supporting nervous system health and energy metabolism.

Pros
  • Uses highly bioavailable Mecobalactive (Methylcobalamin) form of B12.
  • Includes L-5-MTHF for comprehensive methylation support.
  • Reputable brand with positive online reviews.
  • Provides a good dosage for daily support and effectiveness.
Cons
  • High price per serving compared to many other B12 options, which might make it less accessible for some users.
$25.00($0.41 per serving)
Amazon
$ 25.00
Pure Formulas
$ 25.00
iHerb
$ 25.00
Ingredients
IngredientAmount per serving
Folate (Quatrefolic (6S)-5-Methyltetrahydrofolate, Glucosamine Salt) 1360 mcg DFE
Vitamin B12 (Mecobalactive, Adenosylcobalamin) 1000 mcg
Adults 18–50 Dairy Free
Categories
Vitamin B12 90.0
This product features a premium, active form of Vitamin B12 (Mecobalactive/Methylcobalamin) at a clinically relevant dosage, making it an excellent choice for targeted B12 supplementation. The added L-5-MTHF further enhances its utility within the B-vitamin spectrum for overall health.
Goals
Energy 90.0
Active B12 (Mecobalactive) directly supports cellular energy production and red blood cell formation, which is vital for sustained energy levels. Its bioavailability ensures efficient contribution to metabolic pathways, quickly addressing fatigue.
Brain Health 90.0
Methylcobalamin is crucial for neurotransmitter synthesis and myelin sheath maintenance, directly contributing to optimal brain function and nerve health. The active form allows for immediate utilization in neurological processes, supporting long-term brain vitality.
Mood Support 90.0
Active B12 and folate are essential cofactors in the synthesis of mood-regulating neurotransmitters like serotonin and dopamine, which can significantly impact mood stability. Their direct bioavailability enhances their effectiveness in this role, promoting emotional balance.
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Methyl B-12 2500 mcg Tropical Flavor

Jarrow Formulas
4.7
(3508 ratings)
This alternative combines a very high dose of the preferred methylcobalamin form with an excellent price per serving, offering exceptional value for comprehensive B12 support that excels in efficacy and cost.
99 Value

Vegan B12 2500 mcg

DEVA
4.7
(945 ratings)
Delivers a powerful 2500 mcg of active methylcobalamin at an incredibly low price per serving, making it arguably the best value active B12 product available due to its potent dose and affordability.
93 Value

Fully Active B12 1500 mcg

Doctor's Best
4.7
(30986 ratings)
This product provides a significant dose of the highly absorbable methylcobalamin form at a very competitive price point, making it a strong contender for best value by balancing potency and cost.
98 Performance

Methyl B-12 2500 mcg Tropical Flavor

Jarrow Formulas
4.7
(3508 ratings)
This product offers a higher dosage (2500mcg vs 1000mcg) of the active methylcobalamin form at a significantly lower price per serving, providing a more potent and cost-effective active B12 option.
99 Performance

Vegan B12 2500 mcg

DEVA
4.7
(945 ratings)
It delivers an even higher dose of active methylcobalamin (2500mcg) at an exceptionally low price per serving, making it an outstanding value for maximum B12 support without compromising quality.
93 Performance

Fully Active B12 1500 mcg

Doctor's Best
4.7
(30986 ratings)
While a slightly lower dosage of B12, it provides a highly bioavailable form at an excellent price point, offering superior value and still comprehensive benefits compared to the original's higher cost.