Product Image

Histamine Block Plus

Seeking Health
4.6
(588 ratings)
Thiamin 20 mg
SAMe 100 mg
Niacin 25 mg
Riboflavin 10 mg
Copper 0.5 mg
Product Image
Score 88.0

A premium, multi-faceted supplement specifically formulated to support histamine metabolism, cellular energy, and brain function, utilizing a unique blend of DAO, PQQ, SAMe, and active B vitamins.

Quantity: 60 Capsule(s)Servings size: 2 Capsule(s) (30 servings)
Selected goals:
Other goals:
Energy
Brain Health
Cognitive Support
Cardiovascular Support
Testosterone Support

Score 88.0

A premium, multi-faceted supplement specifically formulated to support histamine metabolism, cellular energy, and brain function, utilizing a unique blend of DAO, PQQ, SAMe, and active B vitamins.

Analysis

Histamine Block Plus by Seeking Health is an advanced supplement designed to address a multifaceted range of health concerns, centered around its unique histamine-blocking capability via DAO2 enzyme from porcine kidney. Beyond this specialized function, it provides robust support for cellular energy, neurological health, and mood through ingredients like LifePQQ and SAMe. The product wisely utilizes activated forms of B vitamins (e.g., Pyridoxal 5-Phosphate, Riboflavin 5-Phosphate) and bioavailable chelated minerals, ensuring better absorption and utilization. While the individual dosages of some general vitamins and minerals might be lower than found in dedicated single-nutrient supplements, their synergistic combination in this formula contributes significantly to its broad therapeutic potential. Its high price per serving reflects the quality and uniqueness of its ingredients.

Pros
  • Contains DAO enzyme for direct support against dietary histamine intolerance, a unique and highly beneficial feature.
  • Includes premium ingredients like PQQ and SAMe, which are excellent for mitochondrial health, cognitive function, and mood support.
  • Utilizes active and bioavailable forms of B vitamins (e.g., P5P, Riboflavin 5-Phosphate) for optimal absorption and utilization.
  • Incorporates chelated mineral forms (e.g., Albion Dimagnesium Malate) for enhanced absorption.
  • Offers a broad spectrum of nutrients that synergistically support multiple bodily systems and general well-being.
Cons
  • The price per serving is relatively high, which might be a barrier for some users considering long-term daily supplementation.
  • Some individual mineral doses (e.g., Copper 0.5mg, Magnesium 50mg) are lower than typically recommended for addressing specific deficiencies or therapeutic effects when used as standalone supplements.
  • Contains porcine-derived DAO, making it unsuitable for individuals adhering to vegetarian, vegan, or certain religious dietary restrictions.
Warnings
  • Contains ingredients derived from porcine (pork), so it is not suitable for vegetarians, vegans, or individuals with specific dietary or religious restrictions.
  • Individuals taking medications, especially antidepressants (due to SAMe), or those with underlying health conditions, should consult a healthcare professional before use.
  • This product is designed to aid in the breakdown of dietary histamine and is not intended to treat severe allergic reactions or anaphylaxis.
$47.48($1.58 per serving)
Amazon
$ 65.00
Pure Formulas
$ 65.00
iHerb
$ 47.48
Ingredients
IngredientAmount per serving
Vitamin C (Ascorbic Acid) 100 mg
Thiamine (Thiamine Hydrochloride) 20 mg
Riboflavin (Riboflavin 5-Phosphate Sodium) 10 mg
Niacin 25 mg
Vitamin B6 (Pyridoxal 5-Phosphate) 7 mg
Pantothenic Acid (D-Calcium Pantothenate) 10 mg
Magnesium (Albion Dimagnesium Malate) 50 mg
Zinc (Zinc Gluconate) 5 mg
Copper (Copper Gluconate) 0.5 mg
Alpha-Ketoglutaric Acid 150 mg
SAMe (Disulfate Ptoluensulfonate) 100 mg
LifePQQ (Pyrroloquinoline Quinone Disodium Salt) 7 mg
DAO2 (Porcine Kidney Extract) 2.1 mg
Gluten Free Adults 18–50 Dairy Free
Categories
SAMe 75.0
The product delivers 100mg of SAMe, which is a beneficial inclusion for mood and methylation support in a combined formula. Dedicated SAMe products often provide 200-400mg, but 100mg is a respectable amount within a broader supplement context.
Thiamin 60.0
With 20mg of Thiamine, the product provides a good dose for general metabolic support. While higher doses are available in specialized Thiamin products (e.g., 100-500mg), it offers a solid contribution within this multi-nutrient blend.
Riboflavin 60.0
The product includes 10mg of Riboflavin in its active 5-phosphate form, which is highly bioavailable and beneficial for energy production. However, standalone Riboflavin supplements often provide higher doses (e.g., 100-400mg) for specific therapeutic applications.
Goals
General Health 90.0
This product offers a robust spectrum of essential vitamins (B-complex, C) and minerals (Magnesium, Zinc, Copper) in bioavailable forms. The unique additions of DAO, PQQ, and SAMe provide comprehensive support extending beyond basic nutritional gaps, making it highly beneficial for overall health maintenance.
Mood Support 90.0
SAMe is a highly effective ingredient for mood regulation, as it plays a crucial role in methylation processes that affect neurotransmitter synthesis (serotonin, dopamine, norepinephrine). B vitamins also provide foundational support for neurological pathways influencing mood.
Brain Health 85.0
PQQ is recognized for its neuroprotective effects and ability to stimulate new mitochondrial growth in brain cells. SAMe contributes to neurotransmitter synthesis and methylation, both vital for optimal brain function and neuronal communication.
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This B-complex delivers a potent 100mg of each major B vitamin in high-quality forms. It offers more robust support for energy, brain health, and metabolism than the B-vitamin components of Histamine Block Plus, making it superior for B-vitamin specific goals.
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