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NAD+ Cell Regenerator

Life Extension
4.7
(3112 ratings)
Niacin 300 mg
Product Image
Score 88.0

A very high-dose NAD+ precursor delivering maximum cellular energy and anti-aging benefits, but at a very premium price point.

Quantity: 30 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Heart Health
Skin Health
Energy
Metabolism Boost

Score 88.0

A very high-dose NAD+ precursor delivering maximum cellular energy and anti-aging benefits, but at a very premium price point.

Dose: 100mg, Quantity: 30
Analysis

This product features a potent 300mg dose of Nicotinamide Riboside (NIAGEN), a cutting-edge compound specifically designed to dramatically elevate NAD+ levels within cells. This higher concentration is intended to provide maximal support for mitochondrial function, cellular repair processes, and overall metabolic efficiency, which are critical for anti-aging and sustained energy. While its scientific backing and potential benefits for advanced cellular health are substantial, the extremely high cost per serving positions it as a premium, specialized supplement. It is best suited for discerning consumers who prioritize aggressive cellular optimization and are willing to invest significantly in these advanced health benefits.

Pros
  • Delivers a powerful 300mg dose of NIAGEN, ensuring maximal NAD+ boosting.
  • Exceptional efficacy for enhancing cellular energy, metabolism, and supporting anti-aging pathways.
  • Utilizes a patented, well-researched, and highly regarded form of nicotinamide riboside.
  • From Life Extension, a highly trusted brand in the longevity and supplement space.
Cons
  • Extremely high price per serving ($1.35), making it one of the most expensive B3-related supplements.
  • Its benefits are primarily for advanced cellular health, not for addressing basic niacin deficiency or cholesterol management.
  • The very high cost can be prohibitive for consistent long-term use for most consumers.
$40.50($1.35 per serving)
iHerb
$ 40.50
Pure Formulas
$ 40.50
Ingredients
IngredientAmount per serving
NIAGEN Nicotinamide Riboside 300 mg
Gluten Free Adults 18–50
Categories
Niacin 88.0
While part of the Niacin family, this product's focus on NAD+ precursorship places it in a specialized, high-performance category. Its exceptional efficacy for cellular energy and anti-aging justifies a very high score, though its premium price limits its accessibility as a general Niacin supplement.
Goals
Energy 98.0
With a substantial 300mg dose of nicotinamide riboside, this product provides an even greater enhancement of cellular NAD+ levels, directly fueling ATP production within mitochondria. This translates to a profound and sustained increase in cellular energy, vitality, and physical endurance, representing a peak performance offering for energy goals.
Metabolism Boost 98.0
Boosting NAD+ to this extent intensely activates sirtuins and other metabolic enzymes that optimize nutrient metabolism, fat oxidation, and glucose regulation. This high-dose supplement pushes metabolic efficiency to a higher level, supporting weight management, blood sugar control, and overall cellular performance.
Heart Health 92.0
The elevated NAD+ levels supported by this higher-dose supplement are crucial for maintaining robust mitochondrial health and cellular resilience within cardiovascular tissues. This promotes efficient energy production in heart muscle cells and supports overall vascular integrity, offering superior cellular-level protection for heart well-being.
88 Value

Niacinamide 500 mg

NOW
4.7
(8865 ratings)
Offers exceptional value, providing a high dose of flush-free niacin from a reputable brand at a fraction of the cost of NAD+ precursors ($0.06/serving vs $1.35), making it a smart choice for effective B3 supplementation.
78 Value

Niacin 500 mg

Solaray
4.6
(3680 ratings)
This product provides a substantial 500mg dose of niacin at a very good price ($0.09/serving) from a respected brand, offering strong general metabolic and energy benefits, making it a high-value alternative to the expensive NR.
80 Value

Niacinamide 500 mg

Nature's Way
4.6
(2563 ratings)
A great value choice for a no-flush niacinamide at a 500mg dose and competitive price ($0.09/serving), providing general B3 benefits far more affordably and comfortably than the higher-dose NAD+ regenerator.
85 Performance

Sustained-Release Niacin with niaXtend 500 mg

Doctor's Best
4.7
(660 ratings)
For specific cardiovascular health goals like cholesterol management, this sustained-release niacin is a more directly effective and well-studied alternative than NAD+ precursors, with the added benefit of reduced flushing.
90 Performance

Niacinamide

Thorne
4.7
(1868 ratings)
Thorne is recognized for its superior quality and purity standards, making this niacinamide a 'better' choice for individuals seeking a premium, foundational B3 supplement for general health without the flush or the high cost of advanced NAD+ forms.
80 Performance

Niacin 500 mg

NOW
4.6
(8550 ratings)
This product delivers a well-regarded 500mg dose of standard niacin, which is considered more potent for traditional heart health benefits like cholesterol management, making it 'better' for those specific needs if the flush is acceptable.
60 Budget

Niacin 100 mg

21st Century
4.6
(3653 ratings)
At just 2 cents per serving, this offers the most basic and incredibly cheap form of niacin, providing foundational B3 support at a minuscule fraction of the NAD+ regenerator's cost.
65 Budget

Niacin 250 mg

21st Century
4.6
(1563 ratings)
For only 3 cents per serving, this is a very affordable option for a moderate dose of niacin, making it a practical and significantly cheaper alternative for general B3 needs.
70 Budget

Niacinamide 500 mg

21st Century
4.6
(3882 ratings)
Provides a high 500mg dose of non-flushing niacinamide for an incredibly low 4 cents per serving, offering excellent value for robust, comfortable B3 supplementation compared to the expensive NAD+ product.
88 Value

Niacinamide 500 mg

NOW
4.7
(8865 ratings)
Offers exceptional value, providing a high dose of flush-free niacin from a reputable brand at a fraction of the cost of NAD+ precursors ($0.06/serving vs $1.35), making it a smart choice for effective B3 supplementation.
78 Value

Niacin 500 mg

Solaray
4.6
(3680 ratings)
This product provides a substantial 500mg dose of niacin at a very good price ($0.09/serving) from a respected brand, offering strong general metabolic and energy benefits, making it a high-value alternative to the expensive NR.
80 Value

Niacinamide 500 mg

Nature's Way
4.6
(2563 ratings)
A great value choice for a no-flush niacinamide at a 500mg dose and competitive price ($0.09/serving), providing general B3 benefits far more affordably and comfortably than the higher-dose NAD+ regenerator.
85 Performance

Sustained-Release Niacin with niaXtend 500 mg

Doctor's Best
4.7
(660 ratings)
For specific cardiovascular health goals like cholesterol management, this sustained-release niacin is a more directly effective and well-studied alternative than NAD+ precursors, with the added benefit of reduced flushing.
90 Performance

Niacinamide

Thorne
4.7
(1868 ratings)
Thorne is recognized for its superior quality and purity standards, making this niacinamide a 'better' choice for individuals seeking a premium, foundational B3 supplement for general health without the flush or the high cost of advanced NAD+ forms.
80 Performance

Niacin 500 mg

NOW
4.6
(8550 ratings)
This product delivers a well-regarded 500mg dose of standard niacin, which is considered more potent for traditional heart health benefits like cholesterol management, making it 'better' for those specific needs if the flush is acceptable.