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SAMe 400 mg

Protocol For Life Balance
4.9
(46 ratings)
SAMe 400 mg
Product Image
Score 35.0

High-dose SAMe from a professional brand, but severely overpriced for a standalone formulation.

Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Joint Health
Digestive Health

Score 35.0

High-dose SAMe from a professional brand, but severely overpriced for a standalone formulation.

Analysis

Protocol For Life Balance SAMe 400 mg offers a robust dose of SAMe per serving, which is often preferred for more pronounced therapeutic effects across its stated goals. The brand itself caters to healthcare practitioners and is generally associated with quality. However, the cost per serving is very high when compared to other 400mg SAMe supplements on the market that provide similar quality at a fraction of the price. The absence of beneficial B vitamin cofactors also means it doesn't offer comprehensive methylation support.

Pros
  • Provides a higher 400mg dose per serving, which can be more effective for certain conditions.
  • Protocol For Life Balance is a professional-grade brand with a focus on quality.
Cons
  • Very high price per serving, making it considerably less cost-effective than competitors.
  • Does not include essential B vitamin cofactors for optimal SAMe metabolism.
  • Form of SAMe is not specified as 'N/A', and it's a tablet, which requires proper enteric coating for stability, not explicitly mentioned.
Warnings
  • Individuals should consult a healthcare professional before combining SAMe with certain medications, especially antidepressants, due to potential interactions.
$65.47($1.09 per serving)
Pure Formulas
$ 72.00
iHerb
$ 65.47
Ingredients
IngredientAmount per serving
SAMe 400 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Categories
SAMe 35.0
Although this product offers a potent 400mg SAMe dose from a reputable brand, its significantly elevated price compared to market alternatives makes it a less favorable choice within the SAMe collection.
Goals
Mood Support 35.0
The 400mg SAMe dose is often suitable for mood support, but the high cost and absence of B vitamin cofactors detract from its overall value. More cost-effective options exist for this dosage.
Joint Health 35.0
While 400mg SAMe is a common dose for joint health, the product's high price point makes it an expensive choice for long-term management compared to other readily available alternatives.
Digestive Health 35.0
This SAMe product delivers a relevant dose for liver and digestive health. However, its very high price per serving makes it a less desirable option when numerous more affordable 400mg SAMe products are available.
50 Value

SAMe 400 mg

Swanson
4.6
(265 ratings)
Offers a 400mg SAMe dose at a competitive price, providing good potency for the cost from a widely available and established brand.
60 Value

SAMe 400 mg

NOW
4.7
(959 ratings)
Provides a reliable 400mg SAMe dose from a trusted brand, offering a solid balance of quality and value for those seeking this potency.
55 Value

SAMe 400 mg

Source Naturals
4.7
(191 ratings)
A higher 400mg SAMe dose option that balances potency with a reasonable price point, offering good overall value for individuals seeking a higher dosage.
98 Performance

SAMe 200 mg + Cofactors

Metabolic Maintenance
4.6
(30 ratings)
Offers comprehensive support with bioavailable cofactors, enhancing the overall efficacy and methylation benefits, even at a 200mg SAMe dose, making it superior for holistic support.
95 Performance

SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
(11 ratings)
Provides high-quality SAMe with essential, active B vitamin cofactors for a more complete approach to mood and methylation, a step up in formulation.
68 Performance

SAMe (S-Adenosylmethionine)

Pure Encapsulations
4.5
(18 ratings)
While similar in dosage, Pure Encapsulations is renowned for its exceptional purity and quality standards, making it a preferred choice for those prioritizing brand integrity.
90 Budget

SAMe 400 mg

NOW
4.6
(1753 ratings)
Offers the same 400mg SAMe dose at a significantly lower price per serving, providing much better affordability from a well-regarded brand.
84 Budget

SAMe 400 mg

Nutricost
4.7
(728 ratings)
A highly cost-effective option for a 400mg SAMe dose from a stable form, offering significant savings for the same potency.
85 Budget

SAMe 400 mg

Life Extension
4.8
(2467 ratings)
Provides a 400mg SAMe dose at a more competitive price point from a highly reviewed and trusted brand, enhancing its value.
50 Value

SAMe 400 mg

Swanson
4.6
(265 ratings)
Offers a 400mg SAMe dose at a competitive price, providing good potency for the cost from a widely available and established brand.
60 Value

SAMe 400 mg

NOW
4.7
(959 ratings)
Provides a reliable 400mg SAMe dose from a trusted brand, offering a solid balance of quality and value for those seeking this potency.
55 Value

SAMe 400 mg

Source Naturals
4.7
(191 ratings)
A higher 400mg SAMe dose option that balances potency with a reasonable price point, offering good overall value for individuals seeking a higher dosage.
98 Performance

SAMe 200 mg + Cofactors

Metabolic Maintenance
4.6
(30 ratings)
Offers comprehensive support with bioavailable cofactors, enhancing the overall efficacy and methylation benefits, even at a 200mg SAMe dose, making it superior for holistic support.
95 Performance

SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
(11 ratings)
Provides high-quality SAMe with essential, active B vitamin cofactors for a more complete approach to mood and methylation, a step up in formulation.
68 Performance

SAMe (S-Adenosylmethionine)

Pure Encapsulations
4.5
(18 ratings)
While similar in dosage, Pure Encapsulations is renowned for its exceptional purity and quality standards, making it a preferred choice for those prioritizing brand integrity.