Product Image

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
(5265 ratings)
5-HTP 100 mg
Vitamin B6 15 mg
Product Image
Score 80.0

Doctor's Best 5-HTP Enhanced provides a well-dosed combination of 5-HTP and Vitamin B6 for mood, sleep, and stress support, but its product name is misleading regarding Vitamin C content.

Quantity: 120 Veggie Cap(s)Servings size: 1 Veggie Capsule(s) (120 servings)
Selected goals:
Other goals:
Stress Relief
Mood Support
Sleep Support
Energy
Brain Health

Score 80.0

Doctor's Best 5-HTP Enhanced provides a well-dosed combination of 5-HTP and Vitamin B6 for mood, sleep, and stress support, but its product name is misleading regarding Vitamin C content.

Analysis

This product offers a combination of 100mg 5-HTP from Griffonia simplicifolia seed extract and 15mg Vitamin B6 in the form of Pyridoxine Hydrochloride. The 5-HTP dosage is a common and effective amount for mood and sleep support. The inclusion of Vitamin B6 is crucial as it acts as a cofactor in the conversion of 5-HTP to serotonin, enhancing its efficacy. However, the product name explicitly mentions "Vitamin C," which is not listed in the provided ingredients, suggesting a potential discrepancy or omission that could be misleading to consumers, impacting trust.

Pros
  • Contains 100mg of 5-HTP, a widely studied and effective dose for mood and sleep support.
  • Includes Vitamin B6 (15mg) which is a crucial cofactor for the conversion of 5-HTP to serotonin, enhancing its bioavailability and effectiveness.
  • Doctor's Best is a reputable brand with a high volume of positive reviews for their products, indicating general consumer satisfaction and trust.
Cons
  • The product name explicitly states "Enhanced with Vitamins B6 and C," but Vitamin C is not listed in the ingredients, which is misleading and lacks transparency.
  • Uses Pyridoxine Hydrochloride (HCl) for Vitamin B6, which is a common form, but Pyridoxal-5-Phosphate (P-5-P) is often considered more bioavailable and the preferred active form by many nutritionists.
  • While effective, the combination might not be ideal for individuals seeking a pure 5-HTP product or those sensitive to B6 in the HCl form.
$14.62($0.12 per serving)
Amazon
$ 29.24
Vitacost
$ 14.99
Pure Formulas
$ 19.97
iHerb
$ 14.62
Ingredients
IngredientAmount per serving
Vitamin C (Ascorbic Acid) 200 mg
Vitamin B6 (Pyridoxine Hydrochloride) 15 mg
5-HTP (Griffonia simplicifolia Seed Extract) 100 mg
Gluten Free Adults 18–50 Vegan Vegetarian
Categories
5-HTP 85.0
With 100mg of 5-HTP per serving, derived from Griffonia simplicifolia, this product offers a standard and clinically relevant dose that is well-regarded for supporting mood and sleep without being excessively high for typical use.
Vitamin B6 75.0
The product provides 15mg of Pyridoxine Hydrochloride, which is an effective co-factor dose for 5-HTP conversion and general B6 benefits. However, it's not the more bioavailable P-5-P form, which would generally be preferred by nutritionists for optimal absorption and utilization.
Goals
Mood Support 90.0
5-HTP is highly effective for mood support by increasing serotonin levels in the brain, which is often associated with feelings of well-being and happiness. The synergistic action with Vitamin B6 enhances this primary benefit.
Sleep Support 88.0
Serotonin, derived from 5-HTP, is a precursor to melatonin, the hormone that regulates sleep-wake cycles. Therefore, adequate 5-HTP can aid in natural melatonin production, promoting better sleep quality and duration.
Stress Relief 85.0
By promoting balanced serotonin levels, 5-HTP can help regulate mood and reduce feelings of anxiety and stress. Improved sleep quality, a common benefit, also significantly aids in stress management.
90 Value

5-HTP 100 mg

NOW
4.7
(48226 ratings)
Offers 100mg of 5-HTP at a price per serving of 13 cents, which is only slightly more than the analyzed product's 12 cents, but comes from a brand with significantly more positive reviews, indicating higher consumer confidence and proven efficacy for the core ingredient.
88 Value

5-HTP 100 mg

Doctor's Best
4.7
(12256 ratings)
Provides 100mg of 5-HTP at a competitive price per serving of 11 cents, slightly cheaper than the analyzed product. It's from the same brand, suggesting consistent quality for the primary ingredient, and offers a larger supply for extended use.
85 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
(3246 ratings)
Delivers 100mg of 5-HTP for 11 cents per serving, making it a very cost-effective choice for individuals primarily seeking the benefits of 5-HTP. While it lacks B6, its value for the core ingredient is strong.
95 Performance

Vitamin B-6 50 mg

Nature's Way
4.8
(1720 ratings)
This product contains Pyridoxal 5-Phosphate (P-5-P), the active and more bioavailable form of Vitamin B6, which is superior to the Pyridoxine Hydrochloride form in the analyzed product for supporting neurotransmitter synthesis. While it's a pure B6, it addresses the B6 co-factor need for serotonin production more effectively, and could be combined with a pure 5-HTP.
90 Performance

5-HTP 100 mg

NOW
4.7
(48226 ratings)
While similar in 5-HTP dose, this NOW product has an exceptionally high review count (over 46,000), indicating widespread consumer satisfaction and trust. It offers just 5-HTP, allowing users to pair it with their preferred form of B6, such as P5P, for a potentially more optimized regimen.
92 Performance

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
4.8
(1062 ratings)
Offers 40mg of P-5-P, the highly bioavailable and active form of B6, making it a 'better' alternative specifically for optimizing the B6 component which is crucial for 5-HTP's effectiveness. This allows for superior co-factor support, which can be paired with any pure 5-HTP product.
70 Budget

5-HTP 50 mg

NOW
4.7
(13400 ratings)
Offers a lower 5-HTP dose at a significantly cheaper price per serving (7 cents vs 12 cents). While the 5-HTP dose is half, it can be a good starting point for sensitive individuals or for mild support, providing a much more economical option.
88 Budget

5-HTP 100 mg

Doctor's Best
4.7
(12256 ratings)
This product offers the same 100mg 5-HTP dose as the analyzed product, but at a lower price per serving (11 cents vs 12 cents) and in a larger 180-serving bottle, making it a better value for the same primary ingredient, though it does not contain B6.
85 Budget

5-HTP 100 mg Extra Strength

Swanson
4.8
(3246 ratings)
Provides 100mg of 5-HTP per serving at a lower price per serving (11 cents vs 12 cents). While it lacks the added B6, it delivers the core 5-HTP benefit at a more competitive cost, suitable for those who prefer to supplement B6 separately or already get enough.
90 Value

5-HTP 100 mg

NOW
4.7
(48226 ratings)
Offers 100mg of 5-HTP at a price per serving of 13 cents, which is only slightly more than the analyzed product's 12 cents, but comes from a brand with significantly more positive reviews, indicating higher consumer confidence and proven efficacy for the core ingredient.
88 Value

5-HTP 100 mg

Doctor's Best
4.7
(12256 ratings)
Provides 100mg of 5-HTP at a competitive price per serving of 11 cents, slightly cheaper than the analyzed product. It's from the same brand, suggesting consistent quality for the primary ingredient, and offers a larger supply for extended use.
85 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
(3246 ratings)
Delivers 100mg of 5-HTP for 11 cents per serving, making it a very cost-effective choice for individuals primarily seeking the benefits of 5-HTP. While it lacks B6, its value for the core ingredient is strong.
95 Performance

Vitamin B-6 50 mg

Nature's Way
4.8
(1720 ratings)
This product contains Pyridoxal 5-Phosphate (P-5-P), the active and more bioavailable form of Vitamin B6, which is superior to the Pyridoxine Hydrochloride form in the analyzed product for supporting neurotransmitter synthesis. While it's a pure B6, it addresses the B6 co-factor need for serotonin production more effectively, and could be combined with a pure 5-HTP.
90 Performance

5-HTP 100 mg

NOW
4.7
(48226 ratings)
While similar in 5-HTP dose, this NOW product has an exceptionally high review count (over 46,000), indicating widespread consumer satisfaction and trust. It offers just 5-HTP, allowing users to pair it with their preferred form of B6, such as P5P, for a potentially more optimized regimen.
92 Performance

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
4.8
(1062 ratings)
Offers 40mg of P-5-P, the highly bioavailable and active form of B6, making it a 'better' alternative specifically for optimizing the B6 component which is crucial for 5-HTP's effectiveness. This allows for superior co-factor support, which can be paired with any pure 5-HTP product.