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SAMe 400 mg

Source Naturals
4.7
(191 ratings)
SAMe 400 mg
Product Image
Score 75.0

A reasonably priced 400mg SAMe product, but its effectiveness may be compromised by a lack of specified stable form and enteric coating.

Quantity: 30 Tablet(s)Servings size: 1 Tablet(s) (30 servings)
Selected goals:
Other goals:
Mood Support
Joint Health
Digestive Health

Score 75.0

A reasonably priced 400mg SAMe product, but its effectiveness may be compromised by a lack of specified stable form and enteric coating.

Analysis

This SAMe product from Source Naturals provides a substantial 400mg dose, which is often recommended by nutritionists for general mood, joint, and liver support. Its price point is competitive for this dosage, making it an accessible option for many consumers. However, SAMe is inherently unstable and requires specific forms, like S-Adenosyl-L-Methionine Disulfate Tosylate, and enteric coating to survive stomach acid and be properly absorbed in the intestines. The product description does not specify the form of SAMe or mention enteric coating, which raises questions about its bioavailability and shelf life. While online reviews are decent, this lack of transparency on critical formulation aspects can be a concern for discerning users seeking maximum efficacy and stability.

Pros
  • Offers a solid 400mg dose of SAMe, suitable for various health goals.
  • Reasonable price per serving for the dosage provided.
Cons
  • Does not specify the stable form of SAMe (e.g., Disulfate Tosylate), which is important for product integrity.
  • No explicit mention of enteric coating, which is crucial for SAMe's absorption and stability in the digestive tract.
  • Lacks additional B vitamin cofactors that could enhance SAMe metabolism for some individuals.
Warnings
  • SAMe may interact with certain medications, including antidepressants and blood thinners; consult a healthcare professional before use.
$29.75($0.99 per serving)
Pure Formulas
$ 33.59
iHerb
$ 30.43
Vitacost
$ 29.75
Ingredients
IngredientAmount per serving
SAMe 400 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Categories
SAMe 70.0
As a SAMe product, it offers a good standard dosage at a fair price. However, its lack of transparency regarding the SAMe form and enteric coating, which are critical for SAMe's stability and absorption, positions it below top-tier alternatives that explicitly address these factors.
Goals
Mood Support 75.0
The 400mg dose is an effective starting point for mood support, aligning with common recommendations. However, the lack of specified stable form or enteric coating might reduce its overall effectiveness for some users, as SAMe can be degraded by stomach acid.
Joint Health 75.0
At 400mg, this product provides an appropriate dose for supporting joint comfort and mobility. Its potential efficacy for joint health is largely dependent on the stability and absorption of the SAMe, which is not explicitly guaranteed by the product details.
Digestive Health 75.0
The 400mg dose is relevant for liver and digestive health. Similar to other goals, the effectiveness for liver support relies heavily on the bioavailability of the SAMe, which would be enhanced by an enteric coating.
96 Value

SAMe 400 mg

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4.7
(728 ratings)
With 400mg SAMe at $0.59 per serving, this product offers significantly superior value, providing a high dose at a much lower cost than the analyzed product.
95 Value

SAMe 400 mg

NOW
4.6
(1753 ratings)
This alternative combines a strong 400mg SAMe dose with a very good price per serving ($0.68) from a highly trusted brand, offering excellent overall value.
89 Value

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Swanson
4.6
(265 ratings)
This option delivers 400mg of SAMe at $0.69 per serving, providing a great balance of effective dosage and affordability.
95 Performance

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NOW
4.6
(1753 ratings)
From a highly reputable brand, this product offers the same 400mg SAMe dose with a specified stable form and is highly reviewed for efficacy and value, providing a more reliable choice.
98 Performance

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Lake Avenue Nutrition
4.6
(4976 ratings)
This alternative provides 400mg of SAMe in a stable form, backed by an extremely high number of positive reviews, indicating superior consumer satisfaction and likely better enteric coating.
93 Performance

SAMe 400 mg

Life Extension
4.8
(3073 ratings)
A premium brand offering 400mg SAMe with excellent reviews, this product suggests a higher standard of quality and likely superior enteric coating for stability and absorption.
88 Budget

SAMe 400 mg

NOW
4.7
(959 ratings)
This alternative offers the same 400mg SAMe dose at a slightly lower price per serving ($0.88 vs $1.06), from a highly trusted brand.
89 Budget

SAMe 400 mg

Swanson
4.6
(265 ratings)
Offering 400mg SAMe at a very competitive $0.69 per serving, this Swanson product provides better value while specifying a stable SAMe form.
96 Budget

SAMe 400 mg

Nutricost
4.7
(728 ratings)
This alternative provides 400mg SAMe at an exceptionally low price of $0.59 per serving, making it significantly more affordable for the same dosage.
96 Value

SAMe 400 mg

Nutricost
4.7
(728 ratings)
With 400mg SAMe at $0.59 per serving, this product offers significantly superior value, providing a high dose at a much lower cost than the analyzed product.
95 Value

SAMe 400 mg

NOW
4.6
(1753 ratings)
This alternative combines a strong 400mg SAMe dose with a very good price per serving ($0.68) from a highly trusted brand, offering excellent overall value.
89 Value

SAMe 400 mg

Swanson
4.6
(265 ratings)
This option delivers 400mg of SAMe at $0.69 per serving, providing a great balance of effective dosage and affordability.
95 Performance

SAMe 400 mg

NOW
4.6
(1753 ratings)
From a highly reputable brand, this product offers the same 400mg SAMe dose with a specified stable form and is highly reviewed for efficacy and value, providing a more reliable choice.
98 Performance

SAMe 400 mg

Lake Avenue Nutrition
4.6
(4976 ratings)
This alternative provides 400mg of SAMe in a stable form, backed by an extremely high number of positive reviews, indicating superior consumer satisfaction and likely better enteric coating.
93 Performance

SAMe 400 mg

Life Extension
4.8
(3073 ratings)
A premium brand offering 400mg SAMe with excellent reviews, this product suggests a higher standard of quality and likely superior enteric coating for stability and absorption.