Product Image

HomocysteX Plus

Seeking Health
4.8
(1721 ratings)
Vitamin B12 1000 mcg
Riboflavin 25 mg
Vitamin B6 15 mg
Product Image
Score 92.0

A high-quality B vitamin complex featuring all listed ingredients in their active, bioavailable forms, offering superior absorption for various health goals.

Quantity: 60 Capsule(s)Servings size: 1 Capsule(s) (60 servings)
Selected goals:
Other goals:
Fitness
Muscle Gain
Cardiovascular Support
Energy
Brain Health

Score 92.0

A high-quality B vitamin complex featuring all listed ingredients in their active, bioavailable forms, offering superior absorption for various health goals.

Analysis

This supplement excels in its formulation by utilizing active, phosphorylated forms for all three listed B vitamins: MecobalActive for B12, Pyridoxal 5-Phosphate (P-5-P) for B6, and Riboflavin 5-Phosphate Sodium for Riboflavin. This commitment to activated forms is crucial for individuals with compromised conversion pathways, ensuring the body can immediately utilize these nutrients for critical functions like energy production, neurotransmitter synthesis, and cellular metabolism. While its efficacy for supporting brain, mood, and general health is high due to these premium ingredients, its higher price and the absence of folate (a key partner for homocysteine metabolism) are considerations for some consumers.

Pros
  • All listed B vitamins (B12, B6, Riboflavin) are in their active, coenzyme forms, ensuring maximum bioavailability and efficacy for optimal bodily function.
  • MecobalActive is a highly recognized and superior branded form of Methylcobalamin for Vitamin B12, known for its purity and absorption.
  • Produced by Seeking Health, a brand highly regarded by nutritionists and practitioners for its purity and targeted, high-quality formulations.
Cons
  • The product is significantly more expensive per serving (54 cents) compared to many other B-complex supplements, which might be a barrier for budget-conscious users.
  • Similar to its counterpart, it does not explicitly list Folic Acid (B9) in its ingredients, despite the 'HomocysteX' naming which strongly implies a comprehensive homocysteine support formula.
  • Lower review count compared to some other well-established, mass-market brands, though this can be typical for more specialized formulations.
$26.27($0.43 per serving)
Amazon
$ 32.59
Pure Formulas
$ 35.00
iHerb
$ 26.27
Ingredients
IngredientAmount per serving
Riboflavin (Riboflavin 5-Phosphate Sodium) 25 mg
Vitamin B6 (Pyridoxal 5-Phosphate) 15 mg
Folate (Quatrefolic) 1360 mcg DFE
MecobalActive (Vitamin B12) 1000 mcg
Trimethylglycine 700 mg
Gluten Free Adults 18–50 Dairy Free
Categories
Vitamin B12 100.0
MecobalActive is a premium, highly effective form of Methylcobalamin, providing optimal B12 delivery and utilization for cellular processes.
Vitamin B6 95.0
Pyridoxal 5-Phosphate (P-5-P) is the active form of B6, ensuring superior absorption and direct utilization by the body without metabolic conversion.
Riboflavin 95.0
Riboflavin 5-Phosphate Sodium is the active, coenzyme form of Riboflavin, offering enhanced bioavailability and effectiveness compared to standard Riboflavin.
Goals
Energy 95.0
The active forms of B12, B6, and Riboflavin directly support efficient cellular energy production, leading to superior energy support and vitality.
Brain Health 95.0
With all active forms, this complex provides optimal support for neurotransmitter synthesis and overall neurological function, enhancing brain health and cognitive clarity.
Mood Support 95.0
The highly bioavailable B6 and B12 are crucial for the synthesis of mood-regulating neurotransmitters, contributing to excellent mood stabilization and emotional well-being.
88 Value

Activated B-Complex High Bioavailability

Swanson
4.9
(1190 ratings)
This Swanson complex delivers all three B vitamins (B12, B6, Riboflavin) in their active forms for just 20 cents per serving, representing outstanding value for money considering its high quality and active ingredient profile compared to the original's 54 cents.
80 Value

Homocysteine Resist

Life Extension
4.8
(5258 ratings)
At 32 cents per serving, this Life Extension product offers active B12 and B6 forms, making it a very good value for a quality B-complex, even though its Riboflavin is standard, offering a solid blend of efficacy and affordability.
70 Value

B-100

NOW
4.8
(9362 ratings)
For those seeking high potencies of a full B-complex without requiring active forms, NOW's B-100 provides 100mg of B6 and Riboflavin (and 100mcg B12) for only 12 cents per serving, offering excellent value for robust general B vitamin support.
94 Performance

Mega B-150 Balanced B-Complex

NaturesPlus
4.7
(325 ratings)
While some forms are standard, this complex offers exceptionally high dosages (150mg for B6 and Riboflavin, 150mcg active B12), providing a more comprehensive and potent B vitamin support, potentially yielding stronger effects for those needing very high levels.
90 Performance

Migra-Eeze

Life Extension
4.5
(651 ratings)
For individuals specifically seeking high-dose, active Riboflavin (Riboflavin 5-Phosphate at 400mg) for particular needs like migraine support, this single-ingredient product offers a targeted and potent solution not found at such high active doses in the original complex.
98 Performance

Fully Active B12 1500 mcg

Doctor's Best
4.7
(30986 ratings)
For individuals prioritizing maximum B12 efficacy, this alternative offers a higher dosage (1500mcg) of the active Methylcobalamin form at a very efficient price point, making it a superior choice for focused and high-potency B12 supplementation.
88 Budget

Activated B-Complex High Bioavailability

Swanson
4.9
(1190 ratings)
This alternative offers all three B vitamins (B12, B6, Riboflavin) in their active forms (Methylcobalamin, P-5-P, Riboflavin 5-Phosphate) for 20 cents per serving, which is significantly cheaper than the original's 54 cents, making it a high-quality, more affordable active B-complex.
80 Budget

Homocysteine Resist

Life Extension
4.8
(5258 ratings)
While not all B vitamins are in their active forms (Riboflavin is standard), this Life Extension product provides active B12 and B6 at a much lower price (32 cents per serving), offering a good balance of quality and cost for key active B vitamins.
75 Budget

Vitamin B-6 50 mg

Nature's Way
4.8
(1720 ratings)
If the primary need is for active B6, this single ingredient supplement provides 50mg of Pyridoxal 5-Phosphate for only 6 cents per serving, making it an extremely cheap and effective way to get bioavailable B6.
88 Value

Activated B-Complex High Bioavailability

Swanson
4.9
(1190 ratings)
This Swanson complex delivers all three B vitamins (B12, B6, Riboflavin) in their active forms for just 20 cents per serving, representing outstanding value for money considering its high quality and active ingredient profile compared to the original's 54 cents.
80 Value

Homocysteine Resist

Life Extension
4.8
(5258 ratings)
At 32 cents per serving, this Life Extension product offers active B12 and B6 forms, making it a very good value for a quality B-complex, even though its Riboflavin is standard, offering a solid blend of efficacy and affordability.
70 Value

B-100

NOW
4.8
(9362 ratings)
For those seeking high potencies of a full B-complex without requiring active forms, NOW's B-100 provides 100mg of B6 and Riboflavin (and 100mcg B12) for only 12 cents per serving, offering excellent value for robust general B vitamin support.
94 Performance

Mega B-150 Balanced B-Complex

NaturesPlus
4.7
(325 ratings)
While some forms are standard, this complex offers exceptionally high dosages (150mg for B6 and Riboflavin, 150mcg active B12), providing a more comprehensive and potent B vitamin support, potentially yielding stronger effects for those needing very high levels.
90 Performance

Migra-Eeze

Life Extension
4.5
(651 ratings)
For individuals specifically seeking high-dose, active Riboflavin (Riboflavin 5-Phosphate at 400mg) for particular needs like migraine support, this single-ingredient product offers a targeted and potent solution not found at such high active doses in the original complex.
98 Performance

Fully Active B12 1500 mcg

Doctor's Best
4.7
(30986 ratings)
For individuals prioritizing maximum B12 efficacy, this alternative offers a higher dosage (1500mcg) of the active Methylcobalamin form at a very efficient price point, making it a superior choice for focused and high-potency B12 supplementation.