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Mitochondrial NRG

Designs for Health
4.8
★ ★ ★ ★ ★
(48 ratings)
Creatine 550 mg
L-Carnitine 200 mg
Product Image
Score 65.0

Mitochondrial NRG by Designs for Health is a multi-ingredient supplement designed to boost cellular energy and overall vitality through comprehensive mitochondrial support. It combines essential B vitamins, CoQ10, ALA, and antioxidants, but features underdosed quantities of performance-focused ingredients like creatine and L-carnitine. It's a premium-priced option better suited for general health and energy rather than targeted athletic enhancement.

Quantity: 120 Capsule(s)Servings size: 2 Capsule(s) (60 servings)
Selected goals:
Other goals:
Muscle Gain
Fitness
Energy
Brain Health
Heart Health

Score 65.0

Mitochondrial NRG by Designs for Health is a multi-ingredient supplement designed to boost cellular energy and overall vitality through comprehensive mitochondrial support. It combines essential B vitamins, CoQ10, ALA, and antioxidants, but features underdosed quantities of performance-focused ingredients like creatine and L-carnitine. It's a premium-priced option better suited for general health and energy rather than targeted athletic enhancement.

Analysis

Designs for Health Mitochondrial NRG is formulated as a comprehensive mitochondrial support supplement, encompassing a wide array of ingredients aimed at enhancing cellular energy production and overall vitality. Key components include CoQ10, Alpha Lipoic Acid, D-Ribose, L-Carnitine, Creatine, a spectrum of B vitamins, and powerful antioxidants like Curcumin and Trans Resveratrol. While the product utilizes high-quality and bioavailable forms of many ingredients, such as Methylcobalamin B12 and chelated minerals, the dosages for specific performance-enhancing compounds like Creatine (550mg), L-Carnitine (~210mg), and D-Ribose (100mg) are significantly below the clinically effective ranges typically found in standalone supplements. This suggests it's designed more for broad foundational support of mitochondrial health rather than maximizing single-goal outcomes such as substantial muscle gain or aggressive weight loss. Online reviews are limited, but generally positive, though the premium price point of $1.38 per serving requires users to consider if the comprehensive blend justifies the cost compared to targeting specific needs with higher-dosed, individual ingredients.

Pros
  • Comprehensive blend of ingredients supporting mitochondrial health and energy pathways.
  • Includes well-researched compounds like CoQ10, Alpha Lipoic Acid, Curcumin, and Resveratrol.
  • Uses bioavailable forms of B vitamins (Methylcobalamin B12, Pyridoxal 5-Phosphate B6, Riboflavin 5-Phosphate B2) and chelated minerals.
  • Formulated to address multiple health goals simultaneously.
Cons
  • Several key ingredients (Creatine, L-Carnitine, D-Ribose) are significantly underdosed for their clinically effective ranges, especially for specific performance or muscle/weight goals.
  • High price per serving ($1.38) for the given dosages and overall blend compared to single-ingredient alternatives.
  • The broad array of ingredients might mean users pay for compounds they don't specifically need.
Warnings
  • Individuals should consult with a healthcare professional before taking this supplement, especially if on medications or with pre-existing health conditions, due to the variety of active ingredients.
  • The low doses of certain ingredients mean it may not provide the desired strong effects for specific goals like significant muscle gain or weight loss, potentially leading to disappointment if those are the primary expectations.
$82.99($1.38 per serving)
Pure Formulas
$ 82.99
iHerb
$ 91.29
Ingredients
IngredientAmount per serving
Thiamine (Vitamin B1, Thiamine Hydrochloride) 50 mg
Riboflavin (Vitamin B2, Riboflavin 5-Phosphate) 10 mg
Vitamin B3 (Niacinamide) 5 mg
Vitamin B-6 (Pyridoxal 5-Phosphate) 5 mg
Vitamin B12 (Methylcobalamin) 2000 mcg
Magnesium (Creatine MagnaPower) 100 mg
Manganese (TRAACS Manganese Glycinate Chelate) 500 mcg
Creatine (Creatine MagnaPower Magnesium Creatine Chelate) 550 mg
L-Carnitine (L-Carnitine Fumarate) 200 mg
Fumaric Acid (L-Carnitine Fumarate) 150 mg
D-Ribose 100 mg
Malic Acid 100 mg
Succinic Acid 100 mg
Natural Coenzyme Q10 (Ubiquinone) 100 mg
Alpha Lipoic Acid 100 mg
Trans Resveratrol 100 mg
Curcumin C3 Complex(R) (curcuminoids, Curcuminoids) 100 mg
Pantethine 50 mg
Gluten Free Adults 18–50
Categories
L-Carnitine 50.0
The product provides approximately 210mg of L-Carnitine from L-Carnitine Fumarate. This amount is substantially lower than the 500mg to 2000mg found in most dedicated L-Carnitine supplements or the doses typically studied for its various benefits, making it an insufficient standalone source for this compound.
Creatine 30.0
Containing 550mg of Creatine MagnaPower, this product delivers a dose that is well below the clinically effective range of 3-5 grams per day needed for muscle saturation and performance benefits. For individuals seeking the full effects of creatine, a separate, higher-dosed supplement would be necessary.
Goals
Heart Health 75.0
This product contains a strong combination of ingredients beneficial for cardiovascular well-being, including 100mg of CoQ10, 100mg of Trans Resveratrol, and 100mg of Curcumin, which contribute to antioxidant defense, anti-inflammatory processes, and direct support for cardiac energy metabolism.
Cognitive Support 70.0
The blend offers several ingredients known for their neuroprotective and cognitive-enhancing properties, such as Alpha Lipoic Acid, CoQ10, Resveratrol, Curcumin, and a high dose of Methylcobalamin B12 (2000mcg), which support brain mitochondrial function and neurotransmitter synthesis.
Energy 70.0
The comprehensive profile of B vitamins, CoQ10, and intermediates of the Krebs cycle (Succinic, Malic, Fumaric Acids) provides robust foundational support for cellular energy production, which can contribute to overall vitality and combat fatigue.
90 Value

Liquid L-Carnitine 1500 Fruit Punch

ALLMAX
4.8
★★★★★
(1160 ratings)
This liquid L-Carnitine product offers a substantially higher and clinically relevant dose (1500mg vs 200mg in the original) in an easily absorbed liquid form, combined with supportive B vitamins for energy metabolism. It provides significantly better value for targeted fat metabolism and endurance benefits at a much lower cost per serving.
90 Value

Creatine Monohydrate Powder Unflavored

Codeage
4.7
★★★★★
(588 ratings)
Delivering a standard, highly effective dose of 5000mg Creatine Monohydrate, this product far exceeds the 550mg found in the original. It offers superior value and potency for muscle gain, strength, and energy benefits at a significantly lower cost per serving, making it an excellent choice for performance-focused users.
90 Value

Igniter Blue Raspberry

ALLMAX SPORT
4.5
★★★★★
(285 ratings)
This product provides a robust 3000mg dose of Creatine Monohydrate, coupled with a comprehensive blend of energy-boosting B vitamins and amino acids (Taurine, Tyrosine, Citrulline, Beta-Alanine) and caffeine. It offers a powerful and cost-effective solution for fitness, energy, and cognitive support goals, surpassing the original's creatine and energy components for a lower price.
92 Performance

Mega-Liposomal R-ALA Organic Fruit Flavor

Aurora NutraScience
4.4
★★★★★
(669 ratings)
This alternative utilizes a liposomal delivery system, which may offer superior absorption for its key ingredients. It provides significantly higher doses of L-Carnitine (1000mg vs 200mg) and the more potent R-Alpha Lipoic Acid (200mg vs 100mg ALA) while maintaining the same CoQ10 dosage as the original. This makes it a more effective choice for targeted mitochondrial energy and antioxidant support due to enhanced bioavailability and potency.
89 Performance

Kre-Alkalyn EFX

EFX Sports
4.6
★★★★★
(12255 ratings)
For individuals prioritizing creatine benefits for muscle energy and performance, this product offers a higher dose (1500mg vs 550mg in the original) of Kre-Alkalyn, an advanced, buffered form of creatine designed for enhanced stability and absorption. While less comprehensive, its targeted approach to creatine is potentially more effective for athletic goals.
89 Performance

HeartBeat

NaturesPlus
4.8
★★★★★
(5785 ratings)
While individual doses of shared ingredients like L-Carnitine, CoQ10, and Resveratrol are lower than the original, this product excels in its specialized blend for 'Heart Health,' a primary goal of Mitochondrial NRG. It includes potent additions like plant sterols and L-Taurine, making it a highly targeted and effective option for cardiovascular support, potentially surpassing the original's general approach for this specific benefit.
75 Budget

L-Carnitine Fumarate With Biosint Carnitines 855 mg

Doctor's Best
4.6
★★★★★
(11543 ratings)
This alternative offers a significantly higher dose of L-Carnitine Fumarate (855mg compared to 200mg in the original product) at a much lower cost per serving. For individuals primarily seeking L-Carnitine for energy and fat metabolism, this provides a more concentrated and economical option, though it lacks the comprehensive blend of the original.
70 Budget

CoQ10 with L-Carnitine

Mason Natural
4.6
★★★★★
(119 ratings)
This product combines L-Carnitine (250mg) and Coenzyme Q10 (30mg), two key ingredients found in Mitochondrial NRG for energy and heart health, at a significantly lower price per serving. It serves as a more budget-friendly option for foundational mitochondrial support, albeit with lower CoQ10 dosage than the original and fewer overall ingredients.
65 Budget

Instant Energy B12

NOW
4.5
★★★★★
(977 ratings)
Providing a blend of highly bioavailable B vitamins (including a high dose of Methylcobalamin B12, similar to the original) and a foundational dose of Creatine Monohydrate, this alternative is extremely cost-effective. It directly addresses the energy and cognitive support goals of the original product at a fraction of the cost, making it a good value for targeted energy support.
90 Value

Liquid L-Carnitine 1500 Fruit Punch

ALLMAX
4.8
★★★★★
(1160 ratings)
This liquid L-Carnitine product offers a substantially higher and clinically relevant dose (1500mg vs 200mg in the original) in an easily absorbed liquid form, combined with supportive B vitamins for energy metabolism. It provides significantly better value for targeted fat metabolism and endurance benefits at a much lower cost per serving.
90 Value

Creatine Monohydrate Powder Unflavored

Codeage
4.7
★★★★★
(588 ratings)
Delivering a standard, highly effective dose of 5000mg Creatine Monohydrate, this product far exceeds the 550mg found in the original. It offers superior value and potency for muscle gain, strength, and energy benefits at a significantly lower cost per serving, making it an excellent choice for performance-focused users.
90 Value

Igniter Blue Raspberry

ALLMAX SPORT
4.5
★★★★★
(285 ratings)
This product provides a robust 3000mg dose of Creatine Monohydrate, coupled with a comprehensive blend of energy-boosting B vitamins and amino acids (Taurine, Tyrosine, Citrulline, Beta-Alanine) and caffeine. It offers a powerful and cost-effective solution for fitness, energy, and cognitive support goals, surpassing the original's creatine and energy components for a lower price.
92 Performance

Mega-Liposomal R-ALA Organic Fruit Flavor

Aurora NutraScience
4.4
★★★★★
(669 ratings)
This alternative utilizes a liposomal delivery system, which may offer superior absorption for its key ingredients. It provides significantly higher doses of L-Carnitine (1000mg vs 200mg) and the more potent R-Alpha Lipoic Acid (200mg vs 100mg ALA) while maintaining the same CoQ10 dosage as the original. This makes it a more effective choice for targeted mitochondrial energy and antioxidant support due to enhanced bioavailability and potency.
89 Performance

Kre-Alkalyn EFX

EFX Sports
4.6
★★★★★
(12255 ratings)
For individuals prioritizing creatine benefits for muscle energy and performance, this product offers a higher dose (1500mg vs 550mg in the original) of Kre-Alkalyn, an advanced, buffered form of creatine designed for enhanced stability and absorption. While less comprehensive, its targeted approach to creatine is potentially more effective for athletic goals.
89 Performance

HeartBeat

NaturesPlus
4.8
★★★★★
(5785 ratings)
While individual doses of shared ingredients like L-Carnitine, CoQ10, and Resveratrol are lower than the original, this product excels in its specialized blend for 'Heart Health,' a primary goal of Mitochondrial NRG. It includes potent additions like plant sterols and L-Taurine, making it a highly targeted and effective option for cardiovascular support, potentially surpassing the original's general approach for this specific benefit.