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Homocysteine Resist
Life Extension
4.8
★ ★ ★ ★ ★
(5258 ratings)
Vitamin B12 1000 mcg
Riboflavin 25 mg
Vitamin B6 100 mg
Score 80.0
A targeted B vitamin supplement featuring bioavailable B12 and B6 for energy and brain health, though it uses standard Riboflavin and omits Folic Acid despite its homocysteine focus.
Quantity: 60 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 80.0
A targeted B vitamin supplement featuring bioavailable B12 and B6 for energy and brain health, though it uses standard Riboflavin and omits Folic Acid despite its homocysteine focus.
This supplement from Life Extension provides robust dosages of key B vitamins, specifically B12 and B6, in their active forms (Methylcobalamin and Pyridoxal 5-Phosphate). These active forms are highly bioavailable, meaning the body can readily use them without needing to convert them, which is beneficial for individuals with genetic polymorphisms affecting B vitamin metabolism. While these ingredients are highly effective for energy production, neurological support, and contributing to homocysteine breakdown, the Riboflavin (Vitamin B2) is in its standard form. For a product named 'Homocysteine Resist,' the absence of Folic Acid (B9), especially in its active form like L-methylfolate, is a notable limitation, as folate works synergistically with B6 and B12 in the methylation cycle critical for homocysteine reduction.
- Contains highly bioavailable forms of Vitamin B12 (Methylcobalamin) and Vitamin B6 (Pyridoxal 5-Phosphate), ensuring optimal absorption.
- Provides significant dosages of B6 (100mg) and B12 (1000mcg), beneficial for addressing deficiencies and supporting various bodily functions.
- Comes from a reputable brand (Life Extension) with a large number of positive reviews, indicating broad customer satisfaction and trust.
- Riboflavin is provided in the standard form (Vitamin B2) rather than the more bioavailable Riboflavin 5-Phosphate, potentially reducing its efficacy.
- Despite the product's name implying homocysteine management, Folic Acid (B9), a crucial co-factor for homocysteine metabolism alongside B6 and B12, is not listed in the provided ingredients.
- The price per serving is moderate compared to simpler B12 or B6 supplements, though justified by the active forms of some ingredients.
$18.22($0.30 per serving)
 Vitacost | $ 19.50 | |
 Amazon | $ 37.20 | |
 iHerb | $ 18.22 |
| Ingredient | Amount per serving |
|---|---|
| Riboflavin (Vitamin B2) | 25 mg |
| Vitamin B6 (Pyridoxal 5-Phosphate) | 100 mg |
| Folate (Calcium Salt, L-5-Methyltetrahydrofolate) | 8500 mcg DFE |
| Vitamin B12 (Methylcobalamin) | 1000 mcg |
Categories
Vitamin B12 95.0
The product provides 1000mcg of Methylcobalamin, an active and highly bioavailable form of B12, which is excellent for absorption and utilization.
Vitamin B6 95.0
The inclusion of 100mg of Pyridoxal 5-Phosphate (P-5-P) ensures the most active and readily usable form of Vitamin B6, making it highly effective for various metabolic functions.
Riboflavin 70.0
Riboflavin (Vitamin B2) is present at 25mg, which is a good dose, but it's in the standard form rather than the more bioavailable Riboflavin 5-Phosphate, which would offer better absorption.
Goals
Brain Health 88.0
B6 and B12 are critical for neurotransmitter synthesis and nervous system function, with their active forms providing superior support for brain health.
Cognitive Support 88.0
Active B6 and B12 are vital for healthy cognitive function, including memory and focus, by supporting nerve cell health and neurotransmitter balance.
Mood Support 87.0
The roles of B6 and B12 in neurotransmitter production, particularly serotonin and dopamine, directly contribute to mood regulation and stability.
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