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SAMe 400 mg

NOW
4.6
★ ★ ★ ★ ★
(1753 ratings)
SAMe 400 mg
Product Image
Score 95.0

A leading 400mg SAMe product offering exceptional value, stable form, and massive user satisfaction from a highly trusted brand.

Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Joint Health
Digestive Health

Score 95.0

A leading 400mg SAMe product offering exceptional value, stable form, and massive user satisfaction from a highly trusted brand.

Quantity: 30
Analysis

This NOW SAMe product, with 60 servings of 400mg S-Adenosyl-L-Methionine Disulfate Tosylate, represents an outstanding choice for consumers seeking high-potency SAMe at an affordable price. At just $0.68 per serving, it delivers excellent value, especially considering the 400mg dose is often recommended by nutritionists for more pronounced effects in mood, joint, and liver health. The product boasts an extremely high volume of positive online reviews (over 1700), making it one of the most trusted and widely used SAMe supplements. NOW is known for its rigorous quality control, and their SAMe products are typically enteric-coated to ensure optimal absorption and stability in the digestive tract. The primary limitation, common to most standalone SAMe, is the absence of additional B vitamin cofactors, though these can be supplemented separately if desired.

Pros
  • Offers a robust 400mg dose of SAMe, highly effective for various health goals.
  • Uses the stable S-Adenosyl-L-Methionine Disulfate Tosylate form.
  • Exceptional price per serving ($0.68) for a 400mg dose in a 60-count, providing excellent value.
  • Extremely high number of positive online reviews, indicating widespread trust and effectiveness.
  • NOW is a highly reputable brand known for quality and value.
Cons
  • Does not include additional B vitamin cofactors that could enhance SAMe metabolism for some individuals.
Warnings
  • Individuals taking antidepressants or other mood-altering medications should consult a healthcare professional before using SAMe due to potential interactions.
$31.55($0.52 per serving)
Daily Vita
$ 50.70
Amazon
$ 31.55
Pure Formulas
$ 48.17
iHerb
$ 48.71
Vitacost
$ 44.89
Ingredients
IngredientAmount per serving
SAMe (S-Adenosyl-L-Methionine Disulfate Tosylate) 400 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Categories
SAMe 95.0
This SAMe product's combination of effective dosage, stable form, superior value, and overwhelming positive consumer feedback establishes it as a benchmark in the SAMe supplement category.
Goals
Mood Support 95.0
The 400mg dose is highly effective for mood support, and the product's excellent value and reliability make it an ideal choice for consistent, long-term benefits in mood management.
Joint Health 95.0
This product's 400mg dose is a well-established and optimal dosage for joint comfort and mobility, supported by its high quality and competitive pricing for sustained use.
Digestive Health 95.0
The 400mg dose is highly relevant for liver and digestive health. Its strong value makes it an excellent option for consistent daily supplementation to support these vital functions.
96 Value

SAMe 400 mg

Nutricost
4.7
★★★★★
(728 ratings)
Offers an exceptional value for 400mg SAMe at $0.59 per serving, slightly outperforming the analyzed product in pure cost-effectiveness for the same high dose.
98 Value

SAMe 400 mg

Lake Avenue Nutrition
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This alternative provides 400mg SAMe at $0.77 per serving, offering comparable excellent value with an even larger base of highly satisfied customers, making it a very strong contender.
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SAMe 400 mg

California Gold Nutrition
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98 Performance

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Lake Avenue Nutrition
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SAMe 400 mg

Life Extension
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(3073 ratings)
From a premium and highly-respected brand, this alternative provides 400mg SAMe with excellent reviews, often preferred for its strong brand reputation and quality assurance.
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SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
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(11 ratings)
This alternative includes crucial B vitamin cofactors alongside SAMe, which can enhance its overall efficacy, particularly for methylation pathways, a benefit not offered by the analyzed product.
96 Budget

SAMe 400 mg

Nutricost
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93 Budget

SAMe 200

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(263 ratings)
While a lower 200mg dose, this product has a much lower price per serving ($0.25), making it a cheaper option if less potency per dose is desired.
90 Budget

SAMe 200 mg

NOW
4.5
★★★★★
(1732 ratings)
This 200mg alternative from the same brand is less expensive per serving ($0.30), making it a more budget-friendly option for starting doses or lower daily needs.
96 Value

SAMe 400 mg

Nutricost
4.7
★★★★★
(728 ratings)
Offers an exceptional value for 400mg SAMe at $0.59 per serving, slightly outperforming the analyzed product in pure cost-effectiveness for the same high dose.
98 Value

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(4976 ratings)
This alternative provides 400mg SAMe at $0.77 per serving, offering comparable excellent value with an even larger base of highly satisfied customers, making it a very strong contender.
91 Value

SAMe 400 mg

California Gold Nutrition
4.7
★★★★★
(1495 ratings)
Offers 400mg SAMe at $0.80 per serving, providing very good value from a reliable brand with a high volume of positive reviews, serving as a solid alternative for effective and affordable supplementation.
98 Performance

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(4976 ratings)
This alternative is highly comparable in dosage and value but boasts an even higher number of positive reviews, indicating exceptional consumer satisfaction and trustworthiness.
93 Performance

SAMe 400 mg

Life Extension
4.8
★★★★★
(3073 ratings)
From a premium and highly-respected brand, this alternative provides 400mg SAMe with excellent reviews, often preferred for its strong brand reputation and quality assurance.
55 Performance

SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
★★★★★
(11 ratings)
This alternative includes crucial B vitamin cofactors alongside SAMe, which can enhance its overall efficacy, particularly for methylation pathways, a benefit not offered by the analyzed product.