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Methyl-Guard
Thorne
4.9
★ ★ ★ ★ ★
(2974 ratings)
Vitamin B6 20.4 mg
Score 95.0
An excellent, high-quality methylation support supplement with active B vitamins and TMG, highly effective for energy, brain health, and mood support.
Quantity: 180 Capsule(s)Servings size: 3 Capsule(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
leaderboard Score 95.0
An excellent, high-quality methylation support supplement with active B vitamins and TMG, highly effective for energy, brain health, and mood support.
Thorne Methyl-Guard is a standout product specifically designed to support methylation pathways, which are critical for virtually all cellular functions, including neurotransmitter synthesis, detoxification, and energy production. It contains optimal, active forms of B vitamins: 1.2mg of Methylcobalamin (active B12), 20.4mg of Pyridoxal 5-Phosphate (P-5-P, active B6), and 2mg DFE of Folate (Thorne typically uses L-5-MTHF, the active form, though not specified as such in the data). The inclusion of 1.8g of Betaine Anhydrous (TMG) further enhances its methylation support. This precise combination of high-quality, bioavailable ingredients directly addresses the underlying biochemical processes crucial for energy, brain health, and mood stability, making it highly effective for its intended goals. The higher price reflects the premium quality and active forms of ingredients.
- Contains active, highly bioavailable forms of B vitamins (Methylcobalamin B12, P-5-P B6, and likely active Folate).
- Includes Betaine Anhydrous (TMG) for comprehensive methylation support.
- Directly supports critical biochemical pathways related to energy, brain health, and mood.
- Thorne is a reputable brand known for high-quality, professional-grade supplements.
- Higher price per serving compared to basic B-complex or single vitamin supplements.
$49.50($0.82 per serving)
 Walmart | $ 55.00 | |
 Pure Formulas | $ 55.00 | |
 iHerb | $ 49.50 | |
 Vitacost | $ 55.00 |
| Ingredient | Amount per serving |
|---|---|
| Vitamin B6 (Pyridoxal 5-Phosphate) | 20.4 mg |
| Folate | 2 mg DFE |
| Vitamin B12 (Methylcobalamin) | 1.2 mg |
| Betaine Anhydrous (Trimethylglycine) | 1.8 Gram(s) |
Categories
Vitamin B6 95.0
This product contains 20.4mg of Vitamin B6 in its active form, Pyridoxal 5-Phosphate (P-5-P), which is superior to the more common pyridoxine HCl in terms of bioavailability and direct utilization by the body. This is a highly effective and preferred form for B6 supplementation.
Goals
General Health 98.0
Methylation is a foundational process affecting almost every system in the body, including detoxification, DNA repair, and immune function. Providing optimal support for this pathway with bioavailable nutrients offers profound benefits for overall general health and longevity.
Energy 95.0
By optimizing methylation and providing active B vitamins, this product directly supports cellular energy production and metabolic efficiency. Users frequently report improved energy levels due to enhanced biochemical processes.
Brain Health 95.0
Methylation is fundamental for neurotransmitter synthesis and myelin sheath formation, both crucial for optimal brain function. The active forms of B vitamins and TMG provide robust support for cognitive health and neurological integrity.
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