Liver Detox & Blood Refresh

Liver Detox & Blood Refresh

Irwin Naturals4.7 (1,116 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 30 servings
Goals
$20.50 $0.68 per serving

Product analysis

46 out of 100

Liver Detox & Blood Refresh includes milk thistle as its main liver-related ingredient. Evidence from particular preparations and people with liver conditions does not establish routine toxin removal from this broad mixture.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality37

Most forms are unspecified, and the named forms lack enough information for a confident quality comparison. The unidentified blend adds another part of the formula that cannot be checked fully.

Ingredient Transparency61

Amounts are listed, but many forms and the blend’s individual ingredients are not disclosed. Those gaps limit a complete check of the formula’s contents.

Value For Money42

Milk thistle offers fair serving value, while turmeric offers more limited value. Most other ingredients lack enough information for a confident value judgement.

Customer Satisfaction80

Customer feedback is very positive across a substantial number of ratings. The ratings do not establish toxin removal or liver benefits.

Product Focus16

Milk thistle provides the main connection to the stated liver purpose. The many additional herbs and unidentified blend do not establish broader toxin-removal effects.

Format
Softgel
Container
60 Softgel(s)
Per serving
$0.68
Customer rating
4.7 · 1,116 ratings
Report analysis

Goals

Liver & Detox
Impact
High effect
C- Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Selenium · 50 mcgMagnesium · 12.5 mgMilk Thistle · 270 mgZinc · 7.5 mgVitamin C · 50 mg
Study evidence
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Zinc Supportive 30 studies

Ingredients

IngredientAmount per servingScore
Calories
25 Calorie(s)
Total Fat
1.5 Gram(s)
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Vitamin C (Ascorbic Acid)
50 mg
Magnesium (Magnesium Citrate)
12.5 mg
Zinc (Zinc Citrate)
7.5 mg
Selenium (L-Selenomethionine)
50 mcg
Flaxseed Oil
1600 mg
Milk Thistle Seed Extract (Silymarin)
270 mg 66
Burdock Root Extract (Arctium lappa L. Root Extract)
100 mg
Dandelion Root Extract (Taraxacum officinale Root Extract)
100 mg
Echinacea purpurea root extract
75 mg
Marshmallow root extract
75 mg
Fennel seed extract
50 mg
Turmeric, Powder
50 mg 12
Chlorella, Powder
40 mg
Spirulina, Powder (Arthrospira platensis)
40 mg
Cayenne, Powder
30 mg
Red Clover Aerial Extract
15 mg
BioPerine Complex
3 mg
Adults 18–50 Women
Report overview
D- Composition And Label DisclosureA+ Composition And Label DisclosureD+ Commercial Price And Usability
The serving provides 270 mg of milk thistle seed extract at a moderate whole-product serving cost. It lists 45% silymarin and 121.5 mg silymarin.
How this ingredient is rated

Composition and Label Disclosure40

The milk thistle seed extract has a stated 45% silymarin.
Declared Silymarin Concentration
The milk thistle seed extract has a stated 45% silymarin.

Composition and Label Disclosure100

The 270 mg of milk thistle seed extract includes 121.5 mg silymarin.
Extract and Marker Amount Disclosure
The 270 mg of milk thistle seed extract includes 121.5 mg silymarin.

Commercial Price and Usability50

The whole-product serving cost is moderate for the stated milk thistle details.
Selected-Serving Price Comparison
The whole-product serving cost is moderate for the stated milk thistle details.
Turmeric · 50 mg OverallScore12
F Composition And Label DisclosureF Composition And Label DisclosureD- Commercial Price And Usability
A serving lists 50 mg of turmeric powder. The whole-product cost per serving is relatively low. The curcuminoid amount is unclear.
How this ingredient is rated

Composition and Label Disclosure10

The curcuminoid concentration is not specified.
Declared Total Curcuminoid Concentration
The curcuminoid concentration is not specified.

Composition and Label Disclosure0

The curcuminoid amount is unclear.
Preparation and Marker Amount Disclosure
The curcuminoid amount is unclear.

Commercial Price and Usability40

The whole-product cost per serving is relatively low.
Selected-Serving Price Comparison
The whole-product cost per serving is relatively low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics.
    Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
    Randomized trial49 participantsLiver & Detox forMagnesium
  2. Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study.
    Farshidi H; Sobhani AR; Eslami M; Azarkish F; Eftekhar E; Keshavarz M; Soltani N · Journal of cardiovascular pharmacology · 2021
    Randomized trialLiver & Detox forMagnesium
  3. Effects of Synbiotic Food Consumption on Serum Minerals, Liver Enzymes, and Blood Pressure in Patients with Type 2 Diabetes: A Double-blind Randomized Cross-over Controlled Clinical Trial.
    Asemi Z; Aarabi MH; Hajijafari M; Alizadeh SA; Razzaghi R; Mazoochi M; Esmaillzadeh A · International journal of preventive medicine · 2020
    Randomized trialLiver & Detox forMagnesium
  4. Clinical experience with 781 cases of alcoholism evaluated and treated on an inpatient basis by various methods.
    Daus AT; Freeman WM; Wilson J; Aponte C · The International journal of the addictions · 1985
    Observational study781 participantsLiver & Detox forMagnesium
  5. Ionized hypomagnesemia in patients undergoing orthotopic liver transplantation: a complication of citrate intoxication.
    Scott VL; De Wolf AM; Kang Y; Altura BT; Virji MA; Cook DR; Altura BM · Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 1997
    Single-arm trialLiver & Detox forMagnesium
  6. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsLiver & Detox forMilk Thistle
  7. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsLiver & Detox forMilk Thistle
  8. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsLiver & Detox forMilk Thistle
  9. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsLiver & Detox forMilk Thistle
  10. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledLiver & Detox forMilk Thistle
  11. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialLiver & Detox forSelenium
  12. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsLiver & Detox forSelenium
  13. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsLiver & Detox forSelenium
  14. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsLiver & Detox forSelenium
  15. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsLiver & Detox forSelenium
  16. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsLiver & Detox forVitamin C
  17. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsLiver & Detox forVitamin C
  18. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsLiver & Detox forVitamin C
  19. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyLiver & Detox forVitamin C
  20. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsLiver & Detox forVitamin C