Liver Refresh

Liver Refresh

NOW4.8 (21,972 ratings)
Format:Capsule Quantity: 180 Capsule(s) · 60 servings
Goals

Product analysis

55 out of 100

Liver Refresh combines milk thistle with other plant and nutrient ingredients aimed at liver support. Findings depend on specific preparations and do not establish routine removal of toxins.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality37

Some plant compounds and the carnitine form are identified, but comparative ingredient quality remains uncertain. Most forms and the blend composition are unspecified, limiting a full comparison.

Ingredient Transparency56

Declared ingredient amounts make the serving easier to check. Most forms and the blend composition are undisclosed, leaving important details unclear.

Value For Money74

The serving compares favorably for milk thistle and glutathione, while methionine also looks economical. Carnitine is costly for the amount provided, and value for several other ingredients remains uncertain.

Customer Satisfaction93

Customer ratings are very positive. A large review base gives that feedback broad support.

Product Focus30

Liver-related findings depend on the preparation and the people taking it, so they cannot be assumed to apply to the whole formula. Changes in liver markers or antioxidant activity do not establish routine toxin removal.

Format
Capsule
Container
180 Capsule(s)
Per serving
$0.42
Customer rating
4.8 · 21,972 ratings
Report analysis

Goals

Liver & Detox
Impact
High effect
B- Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Milk Thistle · 300 mg

Milk thistle has preparation-specific liver research, with mixed findings in liver disease. Whole herb, silymarin and silybin are distinct materials, and neither generic milk-thistle mass nor a phytosome name establishes equivalence to a successful trial combination. Liver-marker changes do not establish routine removal of unspecified toxins. Glutathione replenishment, NAC's precursor role and alpha lipoic acid's antioxidant mechanisms do not establish routine toxin clearance. Artichoke and turmeric findings are disease- and preparation-specific, with no general benefit established from this formula.

How this product is rated for Liver & Detox

Ingredient fit72

Milk thistle is the credited ingredient within a broader formula.
Goal fit
Milk thistle is the credited ingredient within a broader formula.
Dose adequacy
Milk thistle reaches the saved amount benchmark; the other listed mechanisms add no independent contribution.

Pathways60

Liver cell integrity and fat export is the strongest area in the saved findings. The coverage reflects ingredient roles, not measured toxin removal.
Depth
Liver cell integrity and fat export is the strongest mapped area; the finding does not establish improved clearance of a toxin.
Breadth
Only liver cell integrity and fat export reaches the saved coverage threshold.

Evidence88

Milk thistle leads the saved evidence finding. The credited preparation is recognized in the saved findings.
Evidence strength
Milk thistle leads the saved evidence finding, with the population and outcome limitations described above.
Studied preparation
The saved findings recognize the credited preparation; this does not establish generalized toxin clearance.

Formulation logic100

No unmet partner requirement or configured conflict was found. All credited ingredients clear the amount threshold used for inclusion.
Partner coverage
Each credited ingredient works independently or has its required partner.
Conflicts
No configured conflict was matched among the evaluated combinations.
Effective doses
All credited ingredients clear the inclusion threshold; that threshold is not proof of an effective clinical detoxification dose.
Study evidence

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s)
Milk Thistle extract (Silymarin Flavonoids)
300 mg 96
Herbal-Enzyme Blend
90 mg
L-Glutathione
100 mg 64
N-Acetyl Cysteine
100 mg
Grape seed standardized extract (Polyphenols)
100 mg
Alpha Lipoic Acid
100 mg
L-Carnitine (L-Carnitine Tartrate)
50 mg 44
Scute
50 mg
Schisandra
100 mg
Barberry
30 mg
organic Turmeric
30 mg 12
L-Methionine
20 mg 59
Gluten Free Adults 18–50 Dairy Free
Report overview
Methionine · 20 mg OverallScore59
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
Each serving lists 20 mg of L-methionine, a low amount in this comparison. The whole-product serving costs about $0.42, a relatively low price in this comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

The form is L-methionine; the available facts do not record a purity grade or testing claim.
Methionine Isomer Form
L-methionine is a biologically active form.
Purity and Source Standards
The available facts do not record a purity grade or specific purity-testing claim, so those qualities remain unverified.

Dose, Safety & Label Transparency37

Each serving lists 20 mg of methionine, a low amount in this comparison. The ingredient amount is individually stated.
Methionine Dosage Potency
Each serving lists 20 mg of methionine, a low amount in this comparison.
Transparency of Disclosure
The methionine amount is individually stated as 20 mg per serving.

Value100

A whole-product serving costs about $0.42, a relatively low price in this comparison.
Price per Methionine Serving
A whole-product serving costs about $0.42, a relatively low price in this comparison.
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value
Each serving provides a small 50 mg of L-Carnitine. At the whole-product price, the cost is about $8.40 per gram of L-Carnitine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability72

The evaluation recognizes a form suited to the heart and fitness goals it considers, though saved form details do not identify it. The saved facts do not identify a recognized brand or purity grade.
Chemical Form and Goal Alignment
The evaluation recognizes a form considered aligned with heart and fitness goals; the saved form details do not specify which form.
Branded Material and Purity Standards
The saved facts do not identify a recognized branded carnitine source or a purity grade.

Dose, Safety & Label Transparency32

The serving records 50 mg of active L-Carnitine; a paired source-compound yield is not established in the saved facts.
Elemental L-Carnitine Dosage
A serving provides 50 mg of L-Carnitine, a small amount.
Elemental Yield Disclosure
The active L-Carnitine amount is recorded, but the saved evaluation does not link it to a source-compound amount.

Value10

Based on the whole-product price and recorded active amount, the cost is about $8.40 per gram of L-Carnitine.
Price per Gram of Elemental L-Carnitine
Based on the whole-product price and recorded active amount, the cost is about $8.40 per gram of L-Carnitine.
Glutathione · 100 mg OverallScore64
C- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value
Each serving provides 100 mg of reduced glutathione. A whole-product serving costs about $0.42.
How this ingredient is rated

Active Ingredient Quality & Bioavailability58

The ingredient is identified as reduced glutathione. A branded source is recorded.
Delivery System & Absorption Potential
The ingredient is identified as reduced glutathione; no liposomal or other special delivery method is established in the saved facts.
Branded Sources & Purity Markers
The saved facts record a branded glutathione source, without identifying its name.

Dose, Safety & Label Transparency68

The serving discloses 100 mg of reduced glutathione.
Dosage Potency per Serving
The serving provides 100 mg of reduced glutathione.
Label Transparency
The glutathione amount is individually disclosed as 100 mg per serving.

Value70

A whole-product serving costs about $0.42.
Cost Efficiency by Form
A whole-product serving costs about $0.42.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsLiver & Detox forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsLiver & Detox forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsLiver & Detox forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsLiver & Detox forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledLiver & Detox forMilk Thistle