B Complex Plus
Seeking Health
B Complex Plus
4.8
★ ★ ★ ★ ★
(1613 ratings)
Thiamin 25 mg
Vitamin B5 125 mg
Niacin 95 mg
Choline 50 mg
Biotin 750 mcg
Riboflavin 20 mg
Vitamin B6 20 mg
Score 75.0
A high-potency B-complex featuring activated forms of B vitamins for superior absorption, though its very high niacin content and premium price limit its accessibility for general daily use.
Quantity: 100 Capsule(s)Servings size: 1 Capsule(s) (100 servings)
Selected goals:
Other goals:
Energy
Brain Health
Cognitive Support
Cardiovascular Support
Testosterone Support
leaderboard Score 75.0
A high-potency B-complex featuring activated forms of B vitamins for superior absorption, though its very high niacin content and premium price limit its accessibility for general daily use.
insights Analysis
This B-complex supplement from Seeking Health is notable for its inclusion of activated forms of key B vitamins, such as methylcobalamin and adenosylcobalamin for B12, pyridoxal 5-phosphate (P5P) for B6, and riboflavin 5-phosphate for B2. This commitment to bioavailability is a significant advantage, often recommended by nutritionists for optimal nutrient utilization. The product aims to support a wide range of health goals including energy, metabolism, and brain function, which are well-aligned with the roles of B vitamins. However, the total niacin dose of 380mg, even with the inclusion of inositol hexanicotinate (a no-flush form), is very high and likely to cause a niacin flush in many individuals, which can be an unpleasant side effect. Furthermore, at $30 per 100 servings, the price per serving is on the higher end, making it a premium option that may not be suitable for all budgets.
- Contains highly bioavailable, activated forms of several B vitamins (B2, B6, B12, Folate), enhancing absorption and utilization.
- Provides a comprehensive spectrum of B vitamins in significant, therapeutic doses.
- Includes two forms of Niacin (flushing and non-flushing) for a broader approach to Niacin supplementation.
- The extremely high combined dose of Niacin (380mg) is highly likely to cause a 'niacin flush' (redness, itching, warmth) even with the no-flush form, making it uncomfortable for many users.
- Very high price per serving makes it a less accessible option for daily supplementation and impacts its overall value proposition.
- Some listed goals like 'Testosterone Support' are not directly or substantially addressed by a B-complex alone, potentially creating misleading expectations.
- Individuals sensitive to niacin should be particularly cautious due to the very high dose, as a significant flush is probable.
- Consult a healthcare professional before taking, especially if on other medications or with underlying health conditions, due to the high potency of individual B vitamins.
- This product is not recommended for those looking for a basic, low-dose B-complex for everyday maintenance without potential side effects.
$30.00($0.30 per serving)
 Pure Formulas | $ 30.00 | |
 iHerb | $ 30.00 |
bolt Effectiveness for goals
B vitamins are a group of essential nutrients that play crucial roles in cellular metabolism, energy production, and the proper functioning of the nervous system. They act as coenzymes, helping the body convert food into energy and synthesize new cells. Each B vitamin has unique functions but often works synergistically to support overall health.
Activated forms, such as Riboflavin 5-Phosphate, Pyridoxal 5-Phosphate, and specific coenzyme types of B12 and Folate, are already in the forms the body can readily use. This means they may not require additional conversion steps, which can be beneficial for individuals with genetic variations affecting B vitamin metabolism. This may lead to more efficient utilization in the body.
Mecobalactive (methylcobalamin) and Adenosylcobalamin are two distinct coenzyme forms of Vitamin B12, each with unique roles. Methylcobalamin primarily supports methylation processes and nerve health, while adenosylcobalamin is vital for mitochondrial energy production. Providing both forms aims to support a broader range of B12-dependent metabolic pathways in the body.
Niacin (nicotinic acid) is known for its fundamental role in energy metabolism, while Inositol Hexanicotinate is a form of niacin often associated with a 'no-flush' effect and also supports cardiovascular health. Including both forms aims to provide the benefits of niacin across different physiological pathways. This combination allows for a broader spectrum of niacin's effects.
Choline is an essential nutrient closely related to B vitamins, particularly folate and B12, as it participates in methylation pathways. It is crucial for brain and nerve function, liver health, and the formation of cell membranes. Choline and B vitamins often work together to support various metabolic processes and neurotransmitter synthesis.
schedule Dosage, timing & forms
B vitamins are water-soluble and can generally be taken at any time. Many individuals prefer to take them in the morning with food. This timing may align with their role in energy metabolism and can help avoid potential sleep disruption if taken late in the day.
Active forms are body-ready vitamins that do not require conversion by the liver, which can be beneficial for individuals with genetic variations affecting nutrient metabolism. These forms are often more bioavailable, meaning they can be utilized directly by the body for their metabolic functions. This can ensure more efficient nutrient absorption and utilization.
Niacin (nicotinic acid) can cause a temporary "niacin flush" characterized by redness, itching, and warmth due to vasodilation. Inositol Hexanicotinate is a "no-flush" form of niacin that releases niacin slowly in the body, typically avoiding this uncomfortable side effect. Both forms contribute to overall niacin intake.
Methylcobalamin is primarily involved in methylation processes, crucial for nerve health and detoxification. Adenosylcobalamin is essential for mitochondrial energy production and plays a key role in the metabolism of fats and amino acids. Combining these forms ensures support for both major B12-dependent pathways in the body.
Yes, "Folate" refers to the naturally occurring forms found in foods, while "Folic Acid" is the synthetic form. Many individuals have a genetic variation that reduces their ability to convert folic acid into its active form. Therefore, some supplements use active folate forms, which are readily usable by the body.
health_and_safety Safety & interactions
Niacin, also known as nicotinic acid, can cause a temporary skin flushing, tingling, and warmth due to vasodilation. The supplement contains both Niacin and Inositol Hexanicotinate, with the latter generally causing less flushing. This reaction is usually harmless and often diminishes with continued use.
High doses of biotin can interfere with specific lab tests that use biotin technology, potentially leading to inaccurate results. These tests include those for thyroid hormones, cardiac markers, and certain hormone levels. It is advisable to inform your doctor and stop biotin intake a few days before laboratory testing.
Yes, high doses of folate can correct the megaloblastic anemia associated with vitamin B12 deficiency, but it does not address the neurological damage. This can delay the diagnosis and treatment of a progressive B12 deficiency, potentially leading to irreversible nerve damage. Therefore, ensuring adequate B12 status is important, especially when supplementing with folate.
Yes, it is common and harmless for urine to turn a bright, fluorescent yellow color after taking B vitamin supplements. This effect is primarily due to riboflavin (Vitamin B2), which has a natural yellow pigment. Excess riboflavin that the body doesn't immediately use is excreted by the kidneys.
Some B vitamins can interact with certain medications, though interactions vary by specific vitamin and drug. For instance, Vitamin B6 can interfere with some antiepileptic drugs, and Niacin may interact with statins or blood pressure medications. Always consult a healthcare professional regarding potential interactions with any current medications.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Thiamine | 25 mg |
Riboflavin | 20 mg |
Niacin | 95 mg |
Vitamin B6 | 20 mg |
Folate | 680 mcg DFE |
Vitamin B12 | 50 mcg |
Biotin | 750 mcg |
Pantothenic Acid | 125 mg |
Choline | 50 mg |
Categories
Vitamin B6 95.0
The inclusion of 40mg of Pyridoxal 5-Phosphate (P5P), the active and readily usable form of Vitamin B6, is a major strength. This ensures superior bioavailability and efficacy for various enzymatic reactions.
Riboflavin 95.0
The use of 40mg of Riboflavin 5-Phosphate Sodium, an activated form of Vitamin B2, is highly advantageous. This form is immediately available for cellular use, enhancing its role in energy production and antioxidant support.
Niacin 90.0
The product contains a very high combined dose of Niacin (380mg) from two forms, Niacin and Inositol Hexanicotinate. This provides comprehensive Niacin coverage, but the high total amount makes flushing very likely, which might be a deterrent for general users.
Goals
Energy 85.0
B vitamins are essential coenzymes in cellular energy production, and this product's high potency and activated forms provide robust support for energy levels. However, the potential discomfort from a niacin flush might detract from the perceived energy benefit for some individuals.
Metabolism Boost 85.0
All B vitamins play vital roles in various metabolic pathways, including energy metabolism and nutrient breakdown. The comprehensive and activated forms in this product provide robust support for overall metabolic function, ensuring ample cofactors are available.
Brain Health 80.0
B vitamins, particularly Folate (B9), B6, and B12, are critical for neurotransmitter synthesis and nerve function, directly supporting cognitive processes and mental clarity. The active forms enhance their effectiveness, but the high niacin dose could be distracting for some users seeking mental focus.
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