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Ionic Zinc 50 mg

Trace Minerals
4.5
★ ★ ★ ★ ★
(5214 ratings)
Sulfur 40 mg
Chloride 55 mg
Copper 2 mg
Zinc 50 mg
Product Image
Score64
High-dose liquid zinc includes copper but still exceeds routine daily needs. Use is better limited to a defined short-term plan.
How scoring works
Quantity:2 Liquid(s) • (48 servings)
Goals:
Immunity
Hair Health

Score 64

High-dose liquid zinc includes copper but still exceeds routine daily needs. Use is better limited to a defined short-term plan.
How scoring works
$14.99($0.31 per serving)
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$ 14.99
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$ 14.99
Amazon
$ 14.99
Pure Formulas
$ 14.99
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Analysis

The liquid provides 50 mg zinc sulfate and 2 mg copper sulfate, with chloride, sulfate, magnesium, and boron from trace minerals. Included copper partly addresses the mineral-balance concern created by high zinc.

Zinc sulfate disperses easily but is not a premium form and can be hard on the stomach. The zinc-to-copper ratio remains aggressive for daily long-term use despite the copper inclusion.

The product may fit a short, professionally directed high-zinc plan. A lower-dose zinc with a better-tolerated form is more suitable for ordinary maintenance.

Who is it for
  • Adults with a defined short-term need for high-dose zinc
  • People who prefer liquid zinc
  • Users following professional guidance
Best for
  • Short-term high-zinc supplementation
  • Liquid administration
  • Plans that also require copper

Pros

  • Clearly states zinc and copper amounts
  • Includes copper for balance
  • Liquid is easy to measure

Cons

  • Zinc exceeds the adult daily upper limit
  • Uses sulfate forms
  • Poor fit for long-term maintenance

Warnings

  • The 50 mg zinc serving exceeds the usual adult daily upper limit and may cause nausea or copper imbalance with continued use.
  • Zinc can reduce absorption of tetracycline and quinolone antibiotics; separate timing according to the medicine instructions.
  • Do not stack with other zinc products, and stop use if persistent nausea, vomiting, or metallic taste occurs.

Nutrient quality

63 Moderate impact

Zinc and copper sulfate provide usable minerals, but gentler and better-absorbed forms are available. The zinc amount exceeds a conservative general-use level and creates the main safety weakness.

Ingredient transparency

56 Moderate impact

Zinc and copper amounts are clear, but the trace-mineral complex hides its individual components. Missing inactive ingredients and complete intake directions further limit transparency.

Customer satisfaction

70 High impact

Aggregate customer metrics indicate strong satisfaction from a very large sample. Missing feedback details prevent judging repeated complaints or whether experiences match the intended use.

Value for money

71 High impact

A low serving cost and substantial zinc amount provide apparent value. Excessive dosing, basic sulfate forms, and an opaque mineral complex reduce quality-adjusted value.

Report analysis

Goals

Immunity
Immunity
Impact
High effect
A Goal FitD+ Strength of SupportC- CoverageB Formula Quality
Magnesium · 25 mgZinc · 50 mg

Zinc directly supports immune-cell development and is supplied at a large amount with copper for mineral balance. Liquid delivery may be convenient for people who need an adjustable serving.

Zinc sulfate is a basic form that may cause nausea or stomach cramps. The zinc amount exceeds the usual adult upper intake level and is unsuitable for routine full-dose use without a defined clinical need.

Study evidence
Zinc Supportive 73 studies
Hair Health
Hair Health
Impact
High effect
A- Goal FitC- Strength of SupportC- CoverageB- Formula Quality
Zinc · 50 mg

Zinc can support follicle cell division when low zinc status contributes to shedding, while copper supports mineral balance and hair structure. The formula does not cover structural proteins or other major hair pathways.

Zinc sulfate is a less preferred form, and the 50 mg amount exceeds the usual adult upper intake level. Included copper improves balance, but ongoing use at this zinc amount should be clinically supervised because nausea and mineral disruption remain possible.

Study evidence
Copper Adverse 4 studies
Zinc Supportive 22 studies
Skin Health
Skin Health
Impact
Moderate effect
B- Goal FitC Strength of SupportC- CoverageC+ Formula Quality
Zinc · 50 mgCopper · 2 mg

Zinc supports normal skin repair and barrier function, while copper partly balances a known long-term zinc trade-off. The sulfate form is well disclosed but may be harder on the stomach than gentler forms.

The 50 mg zinc amount exceeds the usual adult daily upper limit and is not suitable for routine long-term use without a specific need. Prolonged high intake can still disturb copper balance and may cause nausea despite the included copper.

Study evidence
Copper Supportive 16 studies
Zinc Supportive 66 studies
General Health
General Health
Impact
Moderate effect
B+ Goal FitD- Strength of SupportC- CoverageB- Formula Quality
Magnesium · 25 mgBoron · 100 mcgZinc · 50 mg

Zinc, copper, and a small magnesium contribution provide focused mineral support for normal immune and enzymatic functions. Copper usefully addresses part of the mineral-balance concern created by a high zinc intake.

The 50 mg zinc amount exceeds the usual adult upper intake level and may cause nausea or other adverse effects with routine use. The zinc sulfate form also offers weaker absorption and tolerance than better organic forms.

Study evidence
Magnesium Supportive 114 studies
Zinc Supportive 60 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C+ Goal FitD Strength of SupportD- CoverageC+ Formula Quality
Magnesium · 25 mgZinc · 50 mgBoron · 100 mcg

Zinc sulfate at 50 mg provides a foundational steroidogenesis mineral, but the amount exceeds the usual adult upper intake level. Copper at 2 mg helps mineral balance but does not remove the risk of nausea or excessive zinc exposure.

The basic sulfate form has lower quality than picolinate or methionine, and the small boron amount adds little endocrine breadth. Routine unsupervised use is poorly suited to long-term testosterone support despite the focused liquid format.

Study evidence
Boron Disputed 3 studies
Zinc Disputed 7 studies
Bone Health
Bone Health
Impact
Moderate effect
C+ Goal FitD Strength of SupportD CoverageC- Formula Quality
Magnesium · 25 mgCopper · 2 mgBoron · 100 mcgZinc · 50 mg

Zinc and copper support enzymes involved in bone matrix formation, while small amounts of magnesium and boron add limited breadth. The liquid format is convenient, but sulfate forms and an incompletely defined trace-mineral blend lower form confidence.

The 50 mg zinc amount exceeds the usual adult upper intake level and is not suitable for routine unsupervised use. It may cause nausea and can disrupt copper balance over time despite the included copper.

Study evidence
Boron Supportive 5 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Zinc Supportive 33 studies

Ingredients

IngredientAmount per serving
Magnesium (Ionic Trace Minerals)
 25 mg
Zinc (Zinc Sulfate)
 50 mg
Copper (Copper Sulfate)
 2 mg
Chloride (Ionic Trace Minerals)
 55 mg
Ionic Trace Minerals Complex
350 mg
Sulfate (Ionic Trace Minerals, Zinc Sulfate)
 40 mg
Boron (Ionic Trace Minerals)
 100 mcg
Gluten Free Adults 18–50 Vegan Dairy Free No Allergies Vegetarian
Report overview
Sulfur (Ionic Trace Minerals, Zinc Sulfate) · 40 mg OverallScore94
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The liquid ionic formula has two disclosed sulfate entries that total 80 mg, placing it in the high-potency tier. Individual mineral amounts and the total trace-mineral complex are clearly listed. The 50 mg zinc dose exceeds the adult daily upper limit and may cause nausea or impair copper status with sustained use.

View ingredientView products
Chloride (Ionic Trace Minerals) · 55 mg OverallScore80
A+ Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyA+ Value

Ionic trace minerals provide chloride in a concentrated mineral complex. The chloride serving is below the collection median and contributes little to electrolyte replenishment. The very low cost per serving provides exceptional value despite the small chloride amount.

View ingredientView products
Copper (Copper Sulfate) · 2 mg OverallScore61
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB+ Value

Copper sulfate is a low-tier inorganic form despite clear labeling and a target-aligned copper amount. The high zinc amount produces a ratio outside the preferred balance and may increase competition between the minerals. The low serving cost provides reasonable value but does not offset the form and balance limitations.

View ingredientView products
Loading alternative details
84 Performance

Zinc-Copper Balance

AOR Advanced Orthomolecular Research Premium
Moderate zinc from citrate and picolinate with copper citrate creates a clearer and more balanced mineral formula than the original high-dose sulfates. Strong zinc, copper, immunity, and general-health alignment supports routine use, though individual intake needs still matter.
81 Performance

Zinc Plus 25 mg

Nature's Answer
A moderate zinc amount from citrate and picolinate is paired with copper gluconate and active vitamin B6. The forms and goal alignment are stronger than the original, although the supplied label appears to list the same zinc amount under two forms and should not be interpreted as additive.
80 Performance

Eye Health

Physician's Choice
Zinc citrate and copper citrate are combined with lutein, zeaxanthin, and antioxidant nutrients for much stronger vision alignment. The wider formula is less suitable for someone seeking zinc alone, and black pepper extract may affect medication absorption.
83 Budget

Zinc 30 mg

Nature's Life
The lower serving cost provides a more moderate zinc amount as picolinate and pairs it with citrate and gluconate copper. Better zinc collection fit and much stronger value evidence make it more suitable for routine use than the original high-dose sulfate formula.
78 Budget

Zinc Copper Amino Acid Chelate with Kelp & Pumpkin Seed

Solaray
The lower serving cost keeps zinc and copper together in clearly named amino acid chelates. Zinc remains high, but the transparent forms and stronger copper alignment improve on the original sulfate-based blend.
76 Budget

Ocuvite Lutein & Antioxidants

Bausch & Lomb
The lower serving cost combines zinc and copper with lutein and antioxidant vitamins for broader vision-oriented coverage. Zinc and copper oxides are less appealing forms, but the zinc amount is lower than the original and the ingredient list is more explicit.
77 Value

Healthy Eyes Lutein and Antioxidants

21st Century
The low serving cost adds antioxidant vitamins, selenium, copper, and lutein to a meaningful zinc amount. Zinc and copper oxides are weaker forms, but the broader formula offers more vision-focused utility than the original.
74 Value

Prostate 600+

Nature's Life
A moderate amount of zinc picolinate with copper gluconate is combined with saw palmetto, pumpkin, pygeum, and amino acids for a distinct men’s-health use. Its serving cost is not lower than the original, but the added targeted ingredients may improve value when prostate support is also desired.
64 Value

Elderberry + Ionic Zinc

Trace Minerals
The zinc sulfate amount is lower than the original and is paired with elderberry for a narrower immunity focus. Copper is omitted and the serving cost is not documented as lower, so its value depends on preferring the combined ingredient rather than mineral balance.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  7. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  8. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  9. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  10. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  11. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  12. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  13. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  14. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  15. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  16. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  17. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  18. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  19. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  20. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  21. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  22. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  23. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  24. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  25. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  26. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  27. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  28. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  29. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  30. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  31. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  32. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  33. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  34. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  35. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  36. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  37. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  38. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  39. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  40. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  41. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  42. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  43. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  44. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  45. Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
    Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
    Randomized trialSkin Health forCopper
  46. Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
    Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
    Randomized trial57 participantsSkin Health forCopper
  47. Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
    Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
    Animal experimentSkin Health forCopper
  48. Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
    Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
    Animal experimentSkin Health forCopper
  49. Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
    Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
    Single-arm trialSkin Health forCopper
  50. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  51. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  52. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  53. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  54. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  55. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  56. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  57. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  58. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  59. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  60. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  61. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  62. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc