Advanced Digestive Enzymes
Thorne
Advanced Digestive Enzymes
4.7
★ ★ ★ ★ ★
(4251 ratings)
Glutamic Acid 480 mg
Score 90.0
A premium, comprehensive digestive enzyme blend with strong support for stomach acid, protein, fat, and carbohydrate digestion, from a highly reputable brand. It is not a direct brain health or cognitive support supplement.
Quantity: 180 Capsule(s)Servings size: 1 Capsule(s) (180 servings)
Selected goals:
Other goals:
Digestive Health
Muscle Gain
Brain Health
Cognitive Support
leaderboard Score 90.0
A premium, comprehensive digestive enzyme blend with strong support for stomach acid, protein, fat, and carbohydrate digestion, from a highly reputable brand. It is not a direct brain health or cognitive support supplement.
insights Analysis
Thorne Advanced Digestive Enzymes is a robust formulation designed to optimize the digestion of all macronutrients. It provides substantial amounts of L-Glutamic Acid Hydrochloride (480mg) and Betaine Hydrochloride (480mg) to support stomach acid levels, which are critical for the initial breakdown of proteins and the absorption of essential minerals. Pepsin (70mg, porcine) specifically targets protein digestion, while Pancreatin (140mg, porcine) supplies a broad range of enzymes including amylase, lipase, and protease, ensuring efficient breakdown of carbohydrates, fats, and remaining proteins. The inclusion of Ox Bile concentrate (80mg) is particularly beneficial for individuals with challenges in fat digestion or gallbladder function. This comprehensive approach is highly regarded by nutritionists and widely supported by positive user reviews for its effectiveness in alleviating a wide array of digestive complaints. Similar to other digestive enzyme products, the stated goals of 'Brain Health, Cognitive Support' are not the primary, direct functions of this supplement, despite the indirect benefits improved digestion offers to overall health.
- Offers a comprehensive enzyme blend for efficient digestion of proteins, fats, and carbohydrates.
- Features high potency Betaine HCl and L-Glutamic Acid HCl for superior stomach acid support.
- Includes Ox Bile concentrate, significantly enhancing fat digestion and nutrient absorption.
- Manufactured by Thorne, a brand highly respected for its quality, purity, and scientific backing.
- Porcine-derived enzymes are generally well-regarded for their compatibility and effectiveness in human digestion.
- The stated goals of Brain Health and Cognitive Support are not the product's direct therapeutic target.
- Comes at a higher price point per serving compared to many simpler or less comprehensive digestive aids.
- The use of porcine-derived ingredients may not align with all dietary restrictions or ethical preferences.
- Individuals with ulcers, gastritis, or hyperacidity should exercise caution and consult a healthcare professional before using, as strong acidifiers can be contraindicated.
- Consult with a healthcare provider before use if pregnant, nursing, or if you have any pre-existing medical conditions or are taking medications, to avoid potential complications or interactions.
$47.70($0.26 per serving)
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bolt Effectiveness for goals
Glutamic acid is a non-essential amino acid, meaning the body can produce it. It plays a crucial role as a neurotransmitter in the brain, involved in learning and memory. It also serves as a precursor for the synthesis of other important molecules like GABA.
Glutamic acid is the most abundant excitatory neurotransmitter in the central nervous system, critical for synaptic plasticity, learning, and memory. However, direct supplementation with glutamic acid might not cross the blood-brain barrier effectively. Its related amino acid, glutamine, which can convert to glutamic acid, is more commonly discussed for brain support.
As a supplement, glutamic acid is primarily studied for its potential roles in brain health, particularly its function as an excitatory neurotransmitter. It's also involved in the metabolism of other amino acids and energy production within the body. However, direct supplementation of glutamic acid itself is not a common practice for general health benefits.
Since glutamic acid is a non-essential amino acid, a healthy body can typically synthesize sufficient amounts from other amino acids. This endogenous production generally means that dietary supplementation might not be necessary for most healthy individuals who consume a balanced diet.
While glutamic acid is a key neurotransmitter in the brain related to cognitive function, direct supplementation may not significantly enhance these functions. The blood-brain barrier regulates its passage, and the brain synthesizes its own glutamic acid from precursors. Research on direct supplementation for cognitive improvement is limited and inconclusive.
schedule Dosage, timing & forms
Typical dosages for glutamic acid supplements can vary, often ranging from 500 mg to 1500 mg per day. It is generally recommended to follow the specific instructions provided on the supplement's label. Consulting with a healthcare professional can help inform individual dosage considerations.
Glutamic acid is commonly found in its L-glutamic acid form in supplements. It can also be found as part of glutamic acid hydrochloride or sometimes in combination with other amino acids. Another common form is Monosodium Glutamate (MSG), which is a salt of glutamic acid primarily used as a flavor enhancer.
Many glutamic acid supplements can be taken with food, which may help improve absorption and reduce the likelihood of digestive discomfort for some individuals. However, specific product instructions should always be consulted for the most accurate guidance. Taking it with water is also generally recommended.
There isn't a universally specified "best" time of day to take glutamic acid, as it can vary. Some supplement manufacturers may suggest taking it with meals to enhance absorption or minimize potential mild stomach upset. Always refer to the product's specific instructions for guidance.
Glutamic acid supplements are typically available in capsule, tablet, or powder forms. These forms offer different ways for individuals to incorporate glutamic acid into their regimen. The choice often depends on personal preference for ease of consumption.
health_and_safety Safety & interactions
Specific safety data for glutamic acid supplementation during pregnancy and breastfeeding is generally insufficient. Given the lack of extensive studies, it is typically recommended that pregnant or breastfeeding individuals avoid supplementing with glutamic acid unless specifically advised by a healthcare professional. Maternal and infant health is a priority.
There is limited specific research on direct interactions between supplemental glutamic acid and many prescription medications. Individuals taking medications for neurological disorders, kidney disease, or liver conditions should exercise caution and consult a healthcare professional. It is always advisable to discuss new supplements with a doctor if you are on medication.
The safety and efficacy of glutamic acid supplements in children have not been extensively studied. Due to insufficient research and the developing nature of a child's physiology, glutamic acid supplementation is generally not recommended for children. Consult a pediatrician for any concerns regarding a child's nutritional needs.
Glutamic acid is generally well-tolerated. However, some individuals may experience mild gastrointestinal upset, such as nausea or stomach cramps, especially when taken in high doses. Headaches or skin reactions are also possible, though less common.
Glutamic acid is generally recognized as safe when consumed as part of a normal diet or in moderate supplement amounts. High doses, however, may cause mild side effects such as headache, nausea, diarrhea, or allergic reactions in sensitive individuals. Some studies on MSG, a salt of glutamic acid, have reported similar mild, transient symptoms in sensitive individuals.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Betaine Hydrochloride | 480 mg |
| L-Glutamic Acid Hydrochloride | 480 mg |
| Pancreatin (Porcine) | 140 mg |
| Ox Bile concentrate | 80 mg |
| Pepsin (Porcine) | 70 mg |
Categories
Glutamic Acid 85.0
Containing a substantial 480mg of L-Glutamic Acid Hydrochloride, this product offers one of the highest dosages among digestive enzyme supplements, effectively contributing to stomach acid production. This significant amount provides strong support for its intended digestive role, making it a key component of its overall efficacy.
Goals
Brain Health 25.0
While exceptional digestion leads to improved nutrient absorption, which is undeniably beneficial for overall health and can indirectly support brain function, this product is not formulated with specific neuroactive compounds. Its primary action is digestive, providing only a general and indirect health benefit to the brain through systemic wellness.
Cognitive Support 25.0
This potent enzyme blend facilitates the breakdown of food and absorption of vital nutrients, contributing to general physiological well-being. However, it lacks specialized ingredients or direct mechanisms typically associated with targeted cognitive enhancement or specific brain health pathways, positioning its role in cognitive support as entirely secondary to its digestive function.