Manganese 50 mg
NaturesPlus
Manganese 50 mg
4.8
★ ★ ★ ★ ★
(403 ratings)
Manganese 50 mg
Score 20.0
A very high-dose Manganese supplement (50mg) in a bioavailable chelated form. This dosage significantly exceeds safe daily limits (UL), posing a substantial risk of toxicity and making it unsuitable for general use, highly recommending medical supervision for any intake.
Quantity: 90 Tablet(s)Servings size: 1 Tablet(s) (90 servings)
Selected goals:
Other goals:
Bone Health
Joint Health
General Health
leaderboard Score 20.0
A very high-dose Manganese supplement (50mg) in a bioavailable chelated form. This dosage significantly exceeds safe daily limits (UL), posing a substantial risk of toxicity and making it unsuitable for general use, highly recommending medical supervision for any intake.
insights Analysis
NaturesPlus Manganese 50 mg is a highly concentrated single-ingredient supplement. It uses a Soy Amino Acid Chelate form of Manganese, which is generally regarded as bioavailable. However, the dosage of 50mg per serving is exceptionally high, significantly surpassing the recommended daily intake (RDI) of 2.3mg and the tolerable upper intake level (UL) of 11mg for adults established by health authorities. Nutritionists and online reviews consistently highlight the dangers of exceeding ULs for trace minerals like manganese, which can lead to neurotoxicity, liver damage, and interference with iron absorption. This product is not suitable for routine supplementation and should only be used under strict medical supervision for specific, diagnosed deficiencies, as its high concentration poses a considerable health risk for unmonitored use.
- Utilizes a bioavailable Soy Amino Acid Chelate form of Manganese, enhancing absorption.
- Offers a very high concentration of Manganese for specific therapeutic needs under medical guidance.
- Provides a cost-effective per-serving option for those requiring such a high dose.
- The 50mg dosage vastly exceeds the Tolerable Upper Intake Level (UL) of 11mg for adults, posing a high risk of toxicity.
- Not suitable for general daily supplementation due to potential for neurological side effects (e.g., manganism) and other adverse health outcomes.
- Regular, unsupervised consumption at this level can interfere with the absorption and metabolism of other essential minerals like iron.
- High risk of manganese toxicity (manganism) with prolonged use, which can lead to neurological symptoms similar to Parkinson's disease.
- Should only be used under strict medical supervision and for specific, diagnosed deficiencies due to the supraphysiological dose.
- Avoid if not directed by a healthcare professional, as serious health consequences can arise from excessive intake.
$10.07($0.11 per serving)
 iHerb | $ 10.07 |
bolt Effectiveness for goals
Manganese is an essential trace mineral involved in numerous bodily functions. It acts as a cofactor for various enzymes, supporting bone formation, metabolism of carbohydrates and fats, and antioxidant defense. Adequate manganese levels are important for overall physiological health.
Manganese is an essential trace mineral involved in numerous physiological processes. It acts as a cofactor for several enzymes crucial for metabolism, bone formation, and antioxidant defense. These enzymes are vital for processes like energy production and protecting cells from damage.
Yes, manganese contributes to bone formation and maintenance. It is a component of enzymes involved in building healthy cartilage and bone tissue. Adequate manganese intake is important for normal bone development and strength.
Yes, manganese plays a role in the formation of healthy bones and cartilage. It is involved in the synthesis of proteoglycans, which are essential components of bone and connective tissue. Adequate manganese intake contributes to bone mineral density.
Manganese is a critical component of the antioxidant enzyme superoxide dismutase (MnSOD). MnSOD is located in the mitochondria and helps protect cells from oxidative stress caused by free radicals. This enzyme converts harmful superoxide radicals into less damaging molecules.
schedule Dosage, timing & forms
The recommended daily intake of manganese for adult men is 2.3 mg, and for adult women, it is 1.8 mg. These amounts are generally met through a balanced diet. Specific needs may vary, and supplements can provide additional manganese if dietary intake is insufficient.
Taking manganese supplements with food is generally recommended. This practice can help minimize potential gastrointestinal discomfort, such as an upset stomach. It may also aid in the absorption of the mineral by the body.
The Tolerable Upper Intake Level (UL) for manganese for adults is 11 mg per day. This limit is set to prevent potential adverse effects from excessive intake. Consuming above this level from supplements may lead to health concerns.
There is no universally established 'best' time to take manganese supplements. However, many recommend taking manganese with a meal. This can help prevent potential gastrointestinal upset and may enhance its absorption.
Manganese is often available in supplements as manganese gluconate, manganese sulfate, manganese ascorbate, or manganese amino acid chelates. These forms are selected for their stability and absorption characteristics. The specific form may influence bioavailability.
health_and_safety Safety & interactions
Excessive intake of manganese, often from occupational exposure or contaminated water, can lead to neurological issues, resembling Parkinson's disease symptoms. These include tremors, difficulty walking, and cognitive problems. High supplemental doses over long periods may also pose risks.
Yes, excessive intake of manganese, especially from supplements or occupational exposure, can lead to toxicity. Manganese toxicity primarily affects the central nervous system, potentially causing neurological disorders resembling Parkinson's disease. Symptoms may include tremors, muscle rigidity, and poor coordination.
Manganese is an essential trace mineral, but excessive intake from supplements can lead to adverse effects. It is generally considered safe when consumed within recommended daily allowances. High doses, particularly for extended periods, should be avoided without professional guidance.
For adults, the Tolerable Upper Intake Level (UL) for manganese from food and supplements is 11 mg per day. Consuming amounts above this level may increase the risk of adverse health effects, particularly neurological issues. This UL is set to protect against potential toxicity.
Symptoms of manganese toxicity, often seen in occupational exposure, primarily affect the central nervous system. These can include tremors, muscle rigidity, impaired balance and coordination, and psychological changes. These symptoms are collectively known as manganism, resembling Parkinson's disease.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Manganese | 50 mg |
Categories
Manganese 15.0
Although the Manganese is in a bioavailable amino acid chelate form, the dosage of 50mg is dangerously high, making it unsuitable for regular intake. This dose greatly exceeds the daily recommended intake and tolerable upper limit, indicating a significant safety concern for consumers seeking a Manganese supplement.
Goals
Bone Health 10.0
Manganese is involved in bone metabolism, but the 50mg dose is excessively high and potentially harmful, offering no additional bone health benefits beyond physiological doses. Safer and more effective bone health support can be found in products containing adequate calcium, vitamin D, and appropriate levels of trace minerals, which this product singularly lacks at a safe level.
Joint Health 10.0
Although Manganese is a co-factor in connective tissue synthesis crucial for joint health, this extremely high dose of 50mg is not shown to provide superior joint health benefits. Instead, it introduces a high risk of adverse effects and toxicity, overshadowing any potential positive impact on joint health from this single, over-dosed ingredient.
General Health 5.0
Manganese is crucial for general health, but this product provides a dose that far exceeds safe limits, potentially leading to adverse effects rather than contributing positively to general well-being. For comprehensive general health support, a balanced multivitamin providing a safe dose of manganese along with other essential nutrients is a much more appropriate and beneficial choice.
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