Magnesium L-Threonate
Dr. Mercola
Magnesium L-Threonate
4.8
★ ★ ★ ★ ★
(7364 ratings)
Magnesium 145 mg
Score 98.0
Dr. Mercola's Magnesium L-Threonate is a premium, highly specialized form known for its unique ability to enhance brain function, mood, and sleep by effectively crossing the blood-brain barrier, though it comes at a higher price.
Quantity: 270 Capsule(s)Servings size: 3 Capsule(s) (90 servings)
Selected goals:
Other goals:
Stress Relief
Mood Support
Bone Health
Sleep Support
General Health
leaderboard Score 98.0
Dr. Mercola's Magnesium L-Threonate is a premium, highly specialized form known for its unique ability to enhance brain function, mood, and sleep by effectively crossing the blood-brain barrier, though it comes at a higher price.
insights Analysis
Dr. Mercola's Magnesium L-Threonate is a premium magnesium supplement specifically valued for its unique ability to cross the blood-brain barrier. This makes it exceptionally effective for cognitive enhancement, mood regulation, and improving sleep quality by influencing brain magnesium levels. While the elemental magnesium quantity (145mg) is lower than other forms, its targeted action and high bioavailability for neurological benefits justify its higher price point. Nutritionists and experts often recommend L-Threonate for specific brain-related goals, recognizing its superiority for these applications over other forms. However, for general systemic magnesium deficiency, it might be an expensive option if brain health isn't the primary concern.
- Magnesium L-Threonate is the most bioavailable form for brain penetration.
- Highly effective for cognitive function, mood improvement, and sleep quality.
- Dr. Mercola is a well-regarded brand in the natural health space.
- Lower risk of laxative effects compared to other forms.
- Significantly more expensive per serving than most other magnesium forms.
- Lower elemental magnesium content compared to other forms (though highly targeted).
- May not be the most cost-effective option for general, systemic magnesium deficiency if brain health is not the primary goal.
$86.97($0.96 per serving)
 Amazon | $ 86.97 | |
 iHerb | $ 95.70 | |
 Vitacost | $ 108.75 |
bolt Effectiveness for goals
The effectiveness of magnesium can vary by its specific form due to differences in bioavailability and targeted uses. For instance, magnesium L-threonate is researched for cognitive support due to its ability to cross the blood-brain barrier. Magnesium citrate is often chosen for digestive regularity, while magnesium glycinate is frequently used for relaxation benefits and high absorption.
Magnesium contributes to the regulation of neurotransmitters and hormones involved in the sleep cycle. Studies indicate that magnesium supplementation may help improve sleep quality, especially in older adults or those with restless leg syndrome. It is often sought for its calming properties that can support relaxation.
Magnesium plays a role in regulating neurotransmitters that promote relaxation and sleep. Some studies indicate that magnesium supplementation may improve sleep quality, especially in older adults or those with insomnia symptoms, by helping to calm the nervous system. More research is needed to fully understand its effects across different populations.
Magnesium contributes to the relaxation of blood vessels and may help regulate blood pressure. Some studies have shown a modest reduction in blood pressure, especially in individuals with hypertension or at risk for it, with magnesium supplementation. The effect can vary based on individual health status and existing conditions.
Magnesium plays a vital role in muscle contraction and relaxation. Some research suggests that magnesium supplementation may help reduce the frequency and intensity of muscle cramps, particularly in individuals experiencing magnesium deficiency. It is a commonly explored option for this purpose.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for magnesium varies by age and sex, generally ranging from 310-420 mg for adult men and 310-320 mg for adult women. These recommendations are for dietary intake from food and supplements combined. It is important to consult current health guidelines for specific age and life stages.
The Recommended Dietary Allowance (RDA) for adult men is 400-420 mg per day, and for adult women, it is 310-320 mg per day. These recommendations can vary slightly based on age and life stage. It's important to consult with a healthcare professional for personalized guidance.
Common forms include magnesium citrate, oxide, glycinate, and L-threonate. Magnesium citrate is often used for bowel regularity, while magnesium oxide has lower bioavailability but is a common, inexpensive form. Magnesium glycinate is typically well-absorbed and gentle on the stomach, and magnesium L-threonate is studied for its potential to cross the blood-brain barrier.
Excessive intake of magnesium from supplements, but not from food, can lead to side effects like diarrhea, nausea, and abdominal cramping. In very high doses, it can cause more serious issues such as low blood pressure, muscle weakness, and irregular heartbeat. The tolerable upper intake level for supplemental magnesium is 350 mg per day for adults.
For healthy adults, the Tolerable Upper Intake Level (UL) for supplemental magnesium is 350 mg per day. This UL specifically applies to magnesium from supplements and medications, not from food or water. Exceeding this limit regularly may lead to adverse effects like diarrhea, nausea, and abdominal cramping.
health_and_safety Safety & interactions
Yes, magnesium supplements can interact with several types of medications. These include certain antibiotics (tetracyclines and quinolones), diuretics, proton pump inhibitors, and bisphosphonates. It's advisable to consult a healthcare professional about potential interactions when taking medications.
Common side effects often involve the digestive system, such as diarrhea, nausea, and abdominal cramping. These effects are typically mild and more likely with higher doses or certain forms like magnesium citrate. Starting with a lower dose and gradually increasing can help mitigate these symptoms.
Common side effects, especially with higher doses, can include diarrhea, nausea, and abdominal cramping. These effects are often dose-dependent and may be mitigated by reducing the amount taken. Different forms of magnesium can also influence gastrointestinal tolerance.
While rare from food sources alone, excessive intake from supplements can lead to hypermagnesemia, particularly in individuals with impaired kidney function. Symptoms may include low blood pressure, lethargy, muscle weakness, and an irregular heartbeat. In severe cases, it can be life-threatening.
Individuals with impaired kidney function should exercise caution and consult a healthcare professional before taking magnesium supplements. Kidneys are responsible for excreting excess magnesium, and compromised function can lead to an accumulation of magnesium in the body. This accumulation can result in hypermagnesemia, which is potentially dangerous.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Magnesium | 145 mg |
Magnesium L-Threonate | 2000 mg |
Categories
Magnesium 98.0
Magnesium L-Threonate is a premium and highly effective form, particularly for neurological benefits, making it an excellent choice for targeted magnesium supplementation.
Goals
Mood Support 100.0
Uniquely effective for mood regulation due to its direct impact on brain magnesium levels and synaptic plasticity.
Sleep Support 100.0
Considered a top choice for sleep due to its ability to promote relaxation and improve sleep quality by modulating brain activity.
Stress Relief 98.0
Its ability to cross the blood-brain barrier directly impacts neurotransmitter function, making it highly effective for reducing stress and anxiety.
Recommended Alternatives
95 Value 
Magnesium Caps 500 mg
Life Extension
4.8
★★★★★
(71620 ratings)
Provides a highly superior magnesium glycinate chelate form at a significantly lower price per serving than L-Threonate, offering exceptional bioavailability and systemic benefits for a much better cost-to-effectiveness ratio.
90 Value 
Chelated Magnesium 133 mg
Swanson
4.8
★★★★★
(5354 ratings)
Offers a premium TRAACS Bisglycinate Chelate, a top-tier bioavailable form, at a remarkably low price per serving compared to L-Threonate, making it an excellent value for systemic magnesium support.
85 Value 
Calcium & Magnesium
NOW
4.7
★★★★★
(41307 ratings)
Utilizes magnesium citrate, a well-absorbed and effective form for general health and relaxation, available at a fraction of the cost per serving compared to L-Threonate, representing significantly better overall value for broad magnesium needs.
95 Performance
Magnesium Caps 500 mg
Life Extension
4.8
★★★★★
(71620 ratings)
While L-Threonate targets the brain, this product's TRAACS Magnesium Lysyl Glycinate Chelate is excellent for overall systemic absorption, stress relief, and muscle function, providing broader benefits for the body.
90 Performance
Chelated Magnesium 133 mg
Swanson
4.8
★★★★★
(5354 ratings)
Contains TRAACS Magnesium Bisglycinate Chelate, which is highly effective for relaxation, mood, and sleep support without the premium cost of L-Threonate, making it a strong contender for overall systemic benefit.
80 Performance 
Target-Mins Magnesium Potassium Aspartate With Other Target-Mins Chelates
Country Life
4.7
★★★★★
(4315 ratings)
Offers a blend of bioavailable magnesium forms including citrate and aspartate, potentially offering a broader spectrum of absorption and benefits for various bodily functions beyond what a single form might provide.
95 Budget
Magnesium Caps 500 mg
Life Extension
4.8
★★★★★
(71620 ratings)
Offers a highly bioavailable chelated magnesium form (Lysyl Glycinate) at a significantly lower price per serving, providing excellent systemic benefits without the premium cost of L-Threonate's brain specificity.
90 Budget
Chelated Magnesium 133 mg
Swanson
4.8
★★★★★
(5354 ratings)
Provides TRAACS Magnesium Bisglycinate Chelate, another top-tier bioavailable form, at a much more affordable price, making it an excellent alternative for general absorption and calming effects.
85 Budget
Calcium & Magnesium
NOW
4.7
★★★★★
(41307 ratings)
Contains magnesium citrate, which is a well-absorbed and effective form for general magnesium needs, at a substantially lower price per serving, offering great value if brain-specific action isn't crucial.
95 Value
Magnesium Caps 500 mg
Life Extension
4.8
★★★★★
(71620 ratings)
Provides a highly superior magnesium glycinate chelate form at a significantly lower price per serving than L-Threonate, offering exceptional bioavailability and systemic benefits for a much better cost-to-effectiveness ratio.
90 Value
Chelated Magnesium 133 mg
Swanson
4.8
★★★★★
(5354 ratings)
Offers a premium TRAACS Bisglycinate Chelate, a top-tier bioavailable form, at a remarkably low price per serving compared to L-Threonate, making it an excellent value for systemic magnesium support.
85 Value
Calcium & Magnesium
NOW
4.7
★★★★★
(41307 ratings)
Utilizes magnesium citrate, a well-absorbed and effective form for general health and relaxation, available at a fraction of the cost per serving compared to L-Threonate, representing significantly better overall value for broad magnesium needs.
95 Performance
Magnesium Caps 500 mg
Life Extension
4.8
★★★★★
(71620 ratings)
While L-Threonate targets the brain, this product's TRAACS Magnesium Lysyl Glycinate Chelate is excellent for overall systemic absorption, stress relief, and muscle function, providing broader benefits for the body.
90 Performance
Chelated Magnesium 133 mg
Swanson
4.8
★★★★★
(5354 ratings)
Contains TRAACS Magnesium Bisglycinate Chelate, which is highly effective for relaxation, mood, and sleep support without the premium cost of L-Threonate, making it a strong contender for overall systemic benefit.
80 Performance
Target-Mins Magnesium Potassium Aspartate With Other Target-Mins Chelates
Country Life
4.7
★★★★★
(4315 ratings)
Offers a blend of bioavailable magnesium forms including citrate and aspartate, potentially offering a broader spectrum of absorption and benefits for various bodily functions beyond what a single form might provide.