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Irwin Naturals
4.5
★ ★ ★ ★ ★
(1080 ratings)
St. John's Wort 300 mg
Calcium 500 mg
Omega-3 647 mg
Fish Oil 2158 mg
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Score87

A specialized blend of St. John's Wort, Omega-3s, and minerals designed for emotional and physical support during hormonal transitions.

How scoring works
Quantity:80 Softgel(s) • (20 servings)
Goals:
Mood Support
Bone Health

Score 87

A specialized blend of St. John's Wort, Omega-3s, and minerals designed for emotional and physical support during hormonal transitions.

How scoring works
$19.99($0.99 per serving)
iHerb
$ 19.99
Amazon
$ 19.99
Pure Formulas
$ 19.99
Vitacost
$ 19.99
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Analysis

Soy isoflavones and Black Cohosh are paired with 300 mg of St. John's Wort to support emotional balance during hormonal shifts. The inclusion of Omega-3 fatty acids from fish oil further assists with cardiovascular health and general wellness. These ingredients work together to address the multifaceted challenges of transitional phases in life.

Calcium and magnesium are provided in meaningful amounts to support bone density and structural integrity. This formula is more versatile than simple mood supplements, targeting several body systems simultaneously. Liquid softgels help with the delivery of the fat-soluble components and botanical extracts.

Standardized St. John's Wort ensures a consistent level of hypericin for maintaining a positive mental state. While the price per serving is higher, it replaces the need for several individual supplements. It provides a focused option for those seeking comprehensive mid-life nutritional support.

Who is it for
  • Women navigating hormonal transitions
  • Users seeking mood and bone support
  • Individuals preferring liquid softgels
Best for
  • Transitional emotional balance
  • Comprehensive mid-life wellness
  • Support for bone and heart health

Pros

  • Includes high-quality fish oil
  • Features standardized herbal extracts
  • Broad nutritional pathway coverage

Cons

  • High price per serving
  • Large softgels may be bulky
  • Not for use by men or pregnant women

Warnings

  • Contains soy and fish allergens
  • Can interact with many prescription drugs
  • Consult a professional if symptoms persist

Nutrient quality

85 Highest impact

Standardized St. John's Wort and Black Cohosh ensure consistent delivery of active compounds like hypericin.

Ingredient transparency

90 Highest impact

Dosages for botanical extracts are clearly disclosed, providing important information on active markers like hypericin. The lack of a specific EPA and DHA breakdown within the fish oil base limits the ability to evaluate omega-3 potency.

Customer satisfaction

92 Highest impact

Consistently high ratings from nearly a thousand users indicate that the product is well-received and effective. User feedback highlights successful outcomes related to hormonal balance and general well-being.

Value for money

83 Highest impact

The multi-nutrient profile provides significant value as a comprehensive support system for women's health. While it is a premium-priced option, the inclusion of standardized extracts and high-quality botanicals justifies the cost.

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Goals

Mood Support
Impact
Highest effect
A Goal FitC+ Strength of SupportA- CoverageA- Formula Quality

Combining standardized St. John's Wort with high-EPA Omega-3s provides a unique dual-pathway strategy for emotional balance. This integration of structural fatty acids and botanical reuptake inhibitors addresses both neuroinflammation and neurotransmitter modulation.

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Bone Health
Impact
High effect
A- Goal FitB Strength of SupportC+ CoverageC+ Formula Quality

Calcium and magnesium are provided in substantial amounts that directly support the structural integrity and mineral density of the bones. Soy isoflavones and omega-3 fatty acids may further assist by supporting a balanced environment for bone remodeling.

While providing a strong foundation of minerals, the absence of vitamins D3 and K2 is a notable omission for ensuring optimal calcium absorption and utilization.

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Cardiovascular Support
Impact
Moderate effect
B- Goal FitD+ Strength of SupportC- CoverageB- Formula Quality

Omega-3 fatty acids from fish oil serve as a primary component for supporting healthy lipid levels and overall heart function. The addition of magnesium contributes to the maintenance of healthy blood pressure and vascular relaxation, though the lack of specific EPA and DHA amounts makes detailed assessment difficult.

While the formula is centered on transitional wellness for women, the inclusion of essential minerals and fatty acids aligns well with foundational cardiovascular needs. The combination of ingredients supports inflammatory balance and provides antioxidant protection for the blood vessels.

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Anti-Inflammatory Support
Impact
Moderate effect
C+ Goal FitD Strength of SupportD CoverageC Formula Quality

A combination of fish oil and botanical extracts supports overall wellness during hormonal transitions. Omega-3 fatty acids contribute to the modulation of inflammatory signals, though the specific concentrations of EPA and DHA remain undisclosed.

While ginger and black pepper are present to support bioavailability, the formula primarily focuses on hormonal balance rather than targeted anti-inflammatory pathways. The modest dosage of omega-3s makes it more suitable for maintenance than intensive support.

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Skin Health
Impact
Lower effect
D+ Goal FitF Strength of SupportD- CoverageD- Formula Quality

Omega-3 fatty acids and soy isoflavones are included to support the skin's lipid barrier and address age-related changes in skin elasticity. Integration of these components aligns with a strategy for maintaining moisture and resilience during hormonal shifts.

Many botanical extracts, such as Black Cohosh and St. John's Wort, are tailored for menopausal comfort rather than direct skin architecture. Absence of specific collagen-building blocks or high-dose humectants suggests a role more suited for general wellness support with secondary skin benefits.

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Ingredients

IngredientAmount per serving
Calories
35 Calorie(s)
Total Fat
2 Gram(s)
Saturated Fat
0.5 Gram(s)
Cholesterol
10 mg
Total Carbohydrates
2 Gram(s)
Protein
2 Gram(s)
Calcium
500 mg
Iron
0.6 mg
Magnesium
200 mg
Sodium
15 mg
Fish Oil
2158 mg
Omega-3 Fatty Acids
647 mg
St. John's Wort Extract
300 mg
Hypericin
0.9 mg
Soy Isoflavones
100 mg
Total Isoflavones
5 mg
Black Cohosh root extract
80 mg
Triterpenoid Saponins
2 mg
Red Clover, Powder
40 mg
Asian Ginseng root extract
31 mg
Chasteberry Fruit Extract
20 mg
BioPerine Complex
6 mg
BioPerine
0 NP
Ginger Rhizome Extract
0 NP
Women Women 50+ Menopause
Report overview
St. John's Wort · 300 mg OverallScore68
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
Standardized to contain a specific amount of hypericin, the extract delivers 300mg per serving in a liquid softgel format. The inclusion of other botanicals and fish oil makes it a specialized blend for hormonal balance. While the quality is high, the cost per clinical dose is notably higher than dedicated herbal options.
View ingredientView products
Calcium · 500 mg OverallScore58
B Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
Combining calcium with botanicals like Black Cohosh and St. John's Wort may support women's health during transitional phases. Additional herbal extracts and fatty acids in the formula explain the higher price point compared to basic mineral supplements. Delivering an elemental mineral dose alongside these co-factors offers a multi-functional approach to bone and hormonal health.
View ingredientView products
Omega-3 · 647 mg OverallScore24
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value
Combining various botanicals and fish oil, the softgels offer a multi-ingredient approach to support wellness. While the total omega-3 content contributes to daily intake, the lack of specific EPA and DHA breakdowns and a lower concentration of actives may be a consideration for those seeking high-potency fatty acids.
View ingredientView products
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Wild Alaskan Salmon Oil 2000 mg

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