L-Histidiine 600 mg
NOW
L-Histidiine 600 mg
4.6
★ ★ ★ ★ ★
(331 ratings)
Histidine 600 mg
Score 80.0
A pure, well-dosed L-Histidine supplement from a reputable brand, ideal for targeted support of immune function and and general metabolic health.
Quantity: 60 Capsule(s)Servings size: 1 Veg Capsule(s) (60 servings)
Selected goals:
Other goals:
Immunity
Detoxification
leaderboard Score 80.0
A pure, well-dosed L-Histidine supplement from a reputable brand, ideal for targeted support of immune function and and general metabolic health.
insights Analysis
L-Histidine 600 mg from NOW is a direct and transparent supplement providing a beneficial dose of this essential amino acid. Its primary benefit lies in its purity, offering 600mg of L-Histidine per capsule, which is a common and effective dosage for individuals looking to supplement this particular amino acid. The product aims to support immune function and detoxification, roles for which L-Histidine does indeed contribute, especially as a precursor to histamine and carnosine, which are involved in various bodily processes, including immune responses and antioxidant defense.
- Provides a substantial 600mg dose of L-Histidine per serving, which is effective for targeted supplementation.
- Single ingredient focus ensures purity and avoids unnecessary additives, appealing to those seeking specific amino acid support.
- NOW is a widely recognized and reputable brand, known for its quality control and product transparency.
- Cost-effective at $0.24 per serving, offering good value for a pure amino acid supplement.
- Offers only L-Histidine, which may not provide the comprehensive benefits of a full-spectrum amino acid complex for broader nutritional support.
- While supportive, its direct impact on general immunity or detoxification might be less pronounced compared to multi-ingredient formulations specifically designed for those goals.
- The benefits for general health may be subtle for individuals who are not deficient in histidine.
- Individuals with histamine intolerance or certain medical conditions, especially those related to histamine metabolism, should consult a healthcare professional before taking L-Histidine.
- As with any supplement, pregnant or nursing women and individuals taking medication should seek medical advice prior to use.
$15.10($0.25 per serving)
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 Amazon | $ 15.58 | |
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bolt Effectiveness for goals
Histidine is an essential amino acid involved in several vital body functions, including the production of histamine and carnosine. Supplementation may support immune response, aid in mineral transport, and contribute to antioxidant defense. Its roles in various metabolic pathways suggest broad, yet specific, impacts on health.
Histidine is a precursor to histamine, a compound central to immune responses and inflammation. It also contributes to carnosine, an antioxidant found in muscle and brain tissue. These roles suggest that adequate histidine levels are important for healthy immune function.
Histidine is an essential amino acid, meaning the human body cannot produce it and it must be obtained through diet or supplementation. It is a precursor to histamine, a compound involved in immune responses, digestion, and neurological functions. Histidine also plays a role in the formation of carnosine, a dipeptide with antioxidant properties, particularly abundant in muscle and brain tissue.
Histidine is a component of carnosine, a dipeptide known for its strong antioxidant and anti-glycation properties. Carnosine helps neutralize free radicals and protect cells from oxidative stress. Therefore, Histidine contributes indirectly to the body's overall antioxidant capacity.
Histidine is a precursor to carnosine, which buffers lactic acid in muscles during high-intensity exercise, potentially delaying fatigue. This mechanism suggests that Histidine, particularly when combined with beta-alanine (the other carnosine precursor), may benefit athletic performance by increasing muscle carnosine levels. Studies often focus on carnosine directly.
schedule Dosage, timing & forms
Yes, the appropriate dosage for Histidine can vary depending on individual dietary intake, specific health goals, and existing nutritional status. Factors such as age, weight, and general health may also influence requirements. It's advisable to consult a healthcare professional for personalized guidance.
Typical dosages for L-Histidine supplements often range from 500 mg to 1000 mg per day. It is important to consult product labels for specific recommendations. Individual needs and the purpose of supplementation may influence the appropriate amount.
L-Histidine can generally be taken with or without food. Some individuals prefer taking amino acid supplements on an empty stomach to potentially enhance absorption. However, taking it with a meal might help prevent mild gastrointestinal discomfort for sensitive individuals.
Typical dosages for histidine supplementation vary widely depending on the intended purpose and individual needs. Doses ranging from 500 mg to 4 grams per day have been explored in research. It is important to consult with a healthcare professional to determine an appropriate and safe dosage.
While specific upper limits for L-Histidine are not universally established, high doses over several grams per day are generally not recommended without professional guidance. Always adhere to the dosage instructions provided on the supplement label. Excessive intake of any amino acid can potentially lead to imbalances.
health_and_safety Safety & interactions
Histidine may potentially interact with certain medications, particularly those affecting histamine levels or gastric acid secretion, such as H2-receptor blockers. It is crucial to inform your healthcare provider about all medications you are taking before starting Histidine supplementation. This ensures there are no adverse interactions.
Histidine is an essential amino acid naturally present in the human body and various foods. When consumed as a supplement within recommended dosages, it is generally considered safe for most healthy adults. However, individuals with pre-existing medical conditions should consult a healthcare professional.
Individuals with kidney or liver disease should use Histidine cautiously, as these conditions can affect amino acid metabolism. Those with bipolar disorder or conditions related to high histamine levels, such as certain mast cell disorders, should also consult a physician. Histidine may theoretically exacerbate symptoms in such cases.
Common side effects from Histidine supplementation are infrequent when taken within suggested dosages. Some individuals might experience mild gastrointestinal discomfort, such as nausea or diarrhea. If any unusual or severe symptoms occur, discontinue use and seek medical advice.
There is insufficient reliable scientific evidence regarding the safety of Histidine supplementation during pregnancy or breastfeeding. Due to this lack of data, it is generally recommended for pregnant and breastfeeding women to avoid Histidine supplements. Always consult a healthcare professional for personalized advice in these situations.
Ingredients
| Ingredient | Amount per serving |
|---|---|
L-Histidine | 600 mg |
Categories
Histidine 90.0
This product is a pure L-Histidine supplement providing a strong 600mg dose per serving, making it highly effective for individuals specifically looking to increase their L-Histidine intake. It represents a focused and efficient way to supplement this particular essential amino acid, aligning perfectly with the 'Histidine' collection category by offering a high-quality, targeted source.
Goals
Immunity 75.0
L-Histidine is an essential amino acid that serves as a precursor to histamine and carnosine, both of which play roles in immune system regulation and antioxidant defense, contributing to overall immune health. While it supports immunity through these pathways, its direct impact on acute immune responses may be less pronounced than more direct immune modulators like Vitamin C or Zinc, placing it as a foundational supportive nutrient rather than a primary immune booster.
Detoxification 70.0
L-Histidine contributes indirectly to detoxification processes by supporting the synthesis of various proteins and enzymes, some of which are involved in metabolizing toxins. Carnosine, derived from histidine, also acts as an antioxidant and may help chelate heavy metals, further aiding cellular detoxification. However, it is not considered a primary or direct detoxification agent like liver-support herbs or specific detox compounds, thus its role is more supportive and foundational in the body's natural cleansing mechanisms.
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