Product Image

Mega-One

Source Naturals
4.7
★ ★ ★ ★ ★
(656 ratings)
Iodine 150 mcg
Manganese 6 mg
PABA 85 mg
Copper 1 mg
Niacin 85 mg
Vitamin B6 85 mg
Molybdenum 100 mcg
Product Image
Score69
A convenient high-potency multi with vitamin D3 and good antioxidant forms, but excessive vitamin B6 and weak major-mineral coverage limit balance.
How scoring works
Quantity:180 Tablet(s) • (180 servings)
Goals:
Energy
Hair Health
Detoxification
Metabolism Boost

Score 69

A convenient high-potency multi with vitamin D3 and good antioxidant forms, but excessive vitamin B6 and weak major-mineral coverage limit balance.
How scoring works
$44.63($0.24 per serving)
iHerb
$ 44.63
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Analysis

Vitamin D3, natural vitamin E, L-selenomethionine, chromium chelate, and buffered vitamin C forms are useful formulation choices. A single tablet covers a wide set of vitamins and trace minerals with clearly listed amounts.

Vitamin B6 is very high for everyday prolonged use, and niacinamide, thiamine, riboflavin, and pantothenic acid are also aggressive. Calcium and magnesium are too low for meaningful mineral support, while folate and B12 use older forms.

The one-tablet serving and large package offer good convenience and value for users seeking a high-potency multi. It is less suitable for people already taking a B-complex or those who need substantial calcium and magnesium.

Who is it for
  • Adults seeking a one-tablet high-potency multi
  • Users who need only modest calcium and magnesium
Best for
  • Broad daily micronutrient coverage
  • Convenient long-term supply

Pros

  • Uses vitamin D3
  • Natural vitamin E form
  • Single-tablet serving

Cons

  • Vitamin B6 is very high
  • Calcium and magnesium are minimal
  • Uses folic acid and cyanocobalamin

Warnings

  • Long-term intake of 85 mg vitamin B6 may contribute to tingling, numbness, or other nerve symptoms.
  • Iron may cause constipation or nausea and is unnecessary for users without an identified need.
  • The high niacinamide amount may add to nausea or liver strain when stacked with other high-dose niacin products.

Nutrient quality

57 Moderate impact

Vitamin D3, buffered vitamin C, natural vitamin E, selenomethionine, and several mineral complexes are useful, while folic acid and cyanocobalamin are less preferred, and core vitamins are substantial, while calcium, magnesium, and potassium are modest. Vitamin B6, niacin, thiamin, riboflavin, and manganese are unnecessarily aggressive for routine use, while several accessory compounds have plausible roles, though their amounts add limited depth.

Ingredient transparency

80 Highest impact

Specific amounts are listed for every supplied active ingredient. No proprietary blend hides active doses, while inactive tablet ingredients are not provided.

Customer satisfaction

71 High impact

The supplied aggregate satisfaction metric is strong, and the feedback volume is sufficient for a reasonably stable aggregate metric. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

69 High impact

Broad coverage and useful forms support value, but excessive B-vitamin amounts reduce practical quality. One tablet provides substantial coverage at a low serving cost, while most additions have a plausible purpose, though some offer limited depth.

Report analysis

Goals

Energy
Energy
Impact
High effect
B+ Goal FitC+ Strength of SupportC+ CoverageB Formula Quality
Iodine · 150 mcgVitamin D · 10 mcgVitamin B5 · 85 mgMagnesium · 20 mgRiboflavin · 85 mgThiamin · 85 mgVitamin B12 · 90 mcgIron · 11 mgPotassium · 10 mg

High-dose B vitamins provide strong metabolic cofactor coverage in a convenient one-tablet formula. Energy relevance is mainly nutritional because no alertness, endurance, or adaptogen active is included.

Cyanocobalamin, folic acid, and magnesium oxide weaken form quality, while vitamin B12 and magnesium remain below the stated targeted levels. The included iron may cause digestive upset and is unnecessary for people who have been advised to avoid supplemental iron.

Study evidence
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Hair Health
Scalp Health and Protection
Hair Health
Impact
High effect
C+ Goal FitC Strength of SupportB- CoverageC Formula Quality
Biotin · 90 mcgVitamin D · 10 mcgZinc · 15 mgIron · 11 mgVitamin C · 250 mg

Iron with vitamin C, zinc, selenium, biotin, iodine, and B vitamins covers several deficiency-related pathways involved in shedding. No structural protein or hormonal active is included, but the nutritional base is broad.

Iron and zinc reach useful maintenance amounts, while biotin and magnesium remain small. The 85 mg vitamin B6 amount is unnecessarily high for routine use and prolonged exposure can cause nerve injury.

Study evidence
Biotin Supportive 4 studies
Iodine No effect 1 study
Iron Disputed 25 studies
Selenium Disputed 7 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies
Detoxification
Detoxification
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC CoverageB- Formula Quality
Folate · 714 mcg DFEVitamin B12 · 90 mcgVitamin B6 · 85 mgMolybdenum · 100 mcgSelenium · 50 mcgMagnesium · 20 mgVitamin E · 67 mgZinc · 15 mgVitamin C · 250 mgCholine · 85 mgRiboflavin · 85 mg

Molybdenum, selenium, zinc, choline, vitamin C, and B vitamins support metabolic enzymes and methylation. The formula offers cofactor support rather than direct liver protection.

No NAC, milk thistle, or standardized liver botanical is present. High B-vitamin amounts add nutritional depth, but folic acid and cyanocobalamin reduce form quality.

Study evidence
Choline Supportive 6 studies
Molybdenum Adverse 1 study
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Zinc Supportive 30 studies
Metabolism Boost
Metabolism Boost
Impact
Moderate effect
D Goal FitD Strength of SupportD- CoverageC+ Formula Quality
Biotin · 90 mcgNiacin · 85 mgVitamin B12 · 90 mcgRiboflavin · 85 mgThiamin · 85 mgVitamin B5 · 85 mgVitamin B6 · 85 mgVitamin D · 10 mcgZinc · 15 mgMagnesium · 20 mg

High-potency B vitamins, iodine, selenium, and chromium support cellular energy and basic thyroid or glucose metabolism. Chromium and selenium are low, while the product lacks a direct thermogenic, carnitine, CoQ10, or insulin-sensitivity active.

The one-tablet format is convenient and several mineral forms are named. The 85 mg B6 amount sits close to a chronic-use safety ceiling, so stacking it with other B6 supplements may raise nerve-injury risk.

Study evidence
Chromium Supportive 47 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Selenium Mixed 28 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per serving
Vitamin A
2850 mcg
Vitamin C (Calcium Ascorbate, Manganese Ascorbic Acid Complex, Zinc Ascorbate)
 250 mg
Vitamin D3 (Cholecalciferol)
 10 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate)
 67 mg
Thiamin
85 mg
Riboflavin
85 mg
Niacin (Niacinamide)
 85 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 85 mg
Folate (Folic Acid)
 714 mcg DFE
Vitamin B12 (Cyanocobalamin)
 90 mcg
Biotin
90 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 85 mg
Calcium (Calcium Ascorbate, Calcium Carbonate)
 40 mg
Iron (Iron Fumarate)
 11 mg
Iodine (Potassium Iodide)
 150 mcg
Magnesium (Magnesium Citrate, Magnesium Oxide)
 20 mg
Zinc (Zinc Ascorbate)
 15 mg
Selenium (L-Selenomethionine, Sodium Selenite)
 50 mcg
Copper (Copper Sebacic Acid Complex)
 1 mg
Manganese (Manganese Ascorbic Acid Complex)
 6 mg
Chromium (Chromium Amino Acid Chelate)
 100 mcg
Molybdenum (Molybdenum Amino Acid Complex)
 100 mcg
Potassium (Potassium Citrate)
 10 mg
Choline Bitartrate
85 mg
PABA
85 mg
Inositol
85 mg
Citrus Bioflavonoid Complex
25 mg
Rutin
21 mg
Hesperidin
5 mg
Boron (Boron Amino Acid Complex)
 1 mg
Adults 18–50 Women
Report overview
Iodine (Potassium Iodide) · 150 mcg OverallScore99
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Potassium iodide provides a stable, water-soluble iodine source with dependable absorption. The elemental amount is well aligned with routine thyroid maintenance and remains within the safe daily range. The very low serving cost creates excellent iodine-specific value.

View ingredientView products
Manganese (Manganese Ascorbic Acid Complex) · 6 mg OverallScore92
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Manganese ascorbic acid complex is an organic complex with useful absorption potential. The 6 mg elemental serving falls within the effective range without exceeding the upper intake limit. Clear elemental disclosure and competitive cost make the formula easy to assess.

View ingredientView products
PABA · 85 mg OverallScore84
A Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value

Clearly identified PABA delivers a standard high-potency multivitamin dose. Immediate release is appropriate at this amount, while missing excipient details leave additive cleanliness uncertain. The one-tablet serving is convenient, and the normalized PABA cost offers moderate value.

View ingredientView products
Loading alternative details
68 Performance

Immune One

Bluebonnet
<p>Vitamin C, vitamin D, zinc, methylfolate, methylcobalamin, vitamin K2, and useful mineral forms create a more focused, lower-dose nutrient profile. Hidden immune and enzyme blends plus lightly dosed supporting minerals make it less complete than the original, but form quality improves and iron is omitted.</p>
60 Performance

Adult's Chewable Delicious Apple Cinnamon Flavor

Natures Plus Source of Life
<p>Methylfolate, methylcobalamin, vitamin D3, natural vitamin E, two K2 forms, and broad minerals improve several forms over the original. High B vitamins, vitamin E, manganese, carbohydrate, and hidden complexes keep the chewable aggressive and crowded.</p>
60 Performance

Completia Diabetic Multi-Vitamin

Nature's Way
<p>Substantial magnesium and several useful mineral forms provide broader mineral depth than the original’s low magnesium amount. Two hidden blends and high vitamin A, vitamin E, B vitamins, and selenium remain significant trade-offs for routine use.</p>
71 Budget

Daily One Caps without Iron

Twinlab
<p>A one-capsule iron-free multivitamin costs less while retaining broad vitamin and trace-mineral coverage. Preformed vitamin A, high folate, B6, selenium, and manganese remain aggressive, but it removes the original’s iron and lowers several 85 mg B-vitamin amounts.</p>
66 Budget

Formula VM-75

Solgar
<p>Broad vitamin coverage and several chelated minerals come at slightly lower recurring cost. Very high B vitamins still create a long-term B6 concern, while vitamin D, magnesium, calcium, and several minerals remain modest.</p>
60 Budget

Alive! Men's Ultra Potency Complete Multivitamin

Nature's Way
<p>Broad nutrient coverage, methylcobalamin, and natural vitamin E provide a lower-cost multivitamin alternative. Basic mineral forms, high thiamine, vitamin D, zinc, and selenium, plus many small blends limit refinement, but the product avoids the original’s iron and 85 mg B-vitamin pattern.</p>
67 Value

Mega-One No Iron

Source Naturals
<p>A closely matched one-tablet formula keeps vitamin D3, buffered vitamin C, natural vitamin E, and several useful mineral forms while removing iron. Its recurring cost is similar and the B6, niacin, thiamine, vitamin A, and manganese amounts remain unnecessarily high.</p>
61 Value

Alive! Once Daily Men's Ultra Potency Complete Multivitamin

Nature's Way
<p>One-tablet dosing and broad multivitamin coverage provide strong convenience at a low recurring cost. Methylcobalamin and natural vitamin E are useful, but oxide minerals, high B vitamins, and many token blends limit ingredient quality.</p>
58 Value

Formula VM-2000

Solgar
<p>Buffered vitamin C, natural vitamin E, some chelated minerals, and added active B6 provide useful formula depth. Serving cost is higher and the dose pattern remains aggressive, while vitamin D2, generic B12, mixed mineral forms, and a hidden blend weaken effective value.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  2. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  3. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  4. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  5. Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
    Guideline / consensusDetoxification forCholine
  6. Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
    Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
    Cross-sectional study20,643 participantsDetoxification forCholine
  7. Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
    Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
    Observational study80 participantsDetoxification forCholine
  8. Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
    Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
    Single-arm trial10 participantsDetoxification forCholine
  9. 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
    Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
    Cohort study88 participantsDetoxification forCholine
  10. Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
    Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
    Cross-sectional study2,267 participantsDetoxification forMolybdenum
  11. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialDetoxification forSelenium
  12. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  13. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  14. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  15. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  16. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  17. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  18. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  19. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  20. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  21. [Therapy of Wilson disease].
    Smolarek C; Stremmel W · Zeitschrift fur Gastroenterologie · 1999
    Narrative reviewDetoxification forZinc
  22. Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
    Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
    Randomized trial69 participantsDetoxification forZinc
  23. Effect of zinc on liver cirrhosis with hyperammonemia: a preliminary randomized, placebo-controlled double-blind trial.
    Katayama K; Saito M; Kawaguchi T; Endo R; Sawara K; Nishiguchi S; Kato A; Kohgo H; Suzuki K; Sakaida I; Ueno Y; Habu D; Ito T; Moriwaki H; Suzuki K · Nutrition (Burbank, Los Angeles County, Calif.) · 2015
    Randomized trial18 participantsDetoxification forZinc
  24. Effects of low dose zinc supplementation on biochemical markers in non-alcoholic cirrhosis: a randomized clinical trial.
    Somi MH; Rezaeifar P; Ostad Rahimi A; Moshrefi B · Archives of Iranian medicine · 2012
    Randomized trial60 participantsDetoxification forZinc
  25. Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.
    Semeya AA; Elgamal R; Othman AAA · Biological trace element research · 2025
    Observational study200 participantsDetoxification forZinc
  26. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  27. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  28. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  29. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  30. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  31. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  32. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  33. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  34. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  35. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  36. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  37. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  38. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  39. [Evaluation of the role of dietary intake in the occurrence of alopecia].
    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
    Case-control study272 participantsHair Health forIodine
  40. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
    Case-control study100,203 participantsHair Health forIron
  41. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
    Meta-analysis10,029 participants36 studies pooledHair Health forIron
  42. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
    Cohort study261 participantsHair Health forIron
  43. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
    Cross-sectional study100 participantsHair Health forIron
  44. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron
  45. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  46. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  47. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  48. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  49. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  50. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  51. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  52. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  53. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  54. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
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    Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
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    Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
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    Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
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    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
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  74. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
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  77. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
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  81. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
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    Adams PW; Wynn V; Folkard J; Seed M · Lancet (London, England) · 1976
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