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SAMe 200 mg

Natural Factors
4.6
(610 ratings)
SAMe 200 mg
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Score92

A 200 mg SAMe tablet with enteric coating for gentle liver and mood support.

How scoring works
Quantity:60 Tablet(s)(60 servings)
Goals:
Detoxification

Score 92

A 200 mg SAMe tablet with enteric coating for gentle liver and mood support.

How scoring works
$34.97($0.58 per serving)
iHerb
$ 34.97
Amazon
$ 34.97
Vitacost
$ 38.45
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Analysis

This supplement provides 200 mg of SAMe, which acts as a primary methyl donor to support detoxification and neurotransmitter balance. The enteric coating is critical because it prevents the SAMe from being destroyed by acid in the stomach.

This fits well for someone who wants a moderate, daily dose of SAMe to maintain their metabolic health. The tablet form is easy to use and provides a stable way to take this moisture-sensitive nutrient.

Pros

  • Enteric-coated for better intestinal delivery
  • Helpful for liver detoxification pathways
  • Gentle 200 mg serving size
  • Reliable brand for quality

Cons

  • Dose may be low for more intensive goals
  • Tablet can be hard for some to swallow
  • Price per serving is a bit high

Warnings

  • Take with plenty of water on an empty stomach
  • Avoid if you have a history of panic attacks
  • Consult a professional if taking psychiatric meds

Nutrient quality

95 Highest impact

A 200 mg dose is well-aligned as a conservative starting amount for supporting methylation and detoxification. Enteric coating is an essential feature that ensures the active nutrient remains viable for intestinal absorption.

Ingredient transparency

99 Highest impact

Labeling clearly specifies the active amount per serving for accurate tracking of daily intake. Serving details and the list of inactive components are fully disclosed, contributing to overall transparency.

Customer satisfaction

94 Highest impact

Strong user ratings across a significant review base reflect good product reliability and performance. Feedback confirms that the product performance aligns well with its intended metabolic support role.

Value for money

75 High impact

The price per serving is higher for a 200 mg dose but reflects the quality of the enteric delivery system. It offers moderate value for those seeking reliable stabilization in a mid-size supply.

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Goals

Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality

S-adenosylmethionine (SAMe) is the primary methyl donor in the body, essential for Phase II methylation pathways. This nutrient supports the liver's ability to neutralize diverse compounds and maintains healthy cellular communication.

The enteric coating ensures that the active compound reaches the small intestine for optimal absorption. It appears well-suited for patients requiring targeted support for methylation-dependent detoxification and metabolic health.

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Ingredients

IngredientAmount per serving
SAMe
200 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
SAMe · 200 mg OverallScore85
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
This 200 mg tablet is a reliable starting point for mood support, utilizing enteric coating for optimal absorption. It features the necessary packaging and stabilization required to maintain its potency on the shelf.
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