SAMe 200 mg
Natural Factors
SAMe 200 mg
4.6
★ ★ ★ ★ ★
(578 ratings)
SAMe 200 mg
Score 78.0
A reliable 200mg SAMe product from a reputable brand, offering good value and positive reviews, suitable for standard supplementation.
Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Joint Health
Digestive Health
leaderboard Score 78.0
A reliable 200mg SAMe product from a reputable brand, offering good value and positive reviews, suitable for standard supplementation.
insights Analysis
This Natural Factors SAMe product provides 200mg of SAMe per serving, a common starting dose for various applications. Natural Factors is a reputable brand known for its quality supplements and adherence to good manufacturing practices. With 559 positive online reviews, it demonstrates a generally satisfactory user experience. The price per serving of $0.58 offers a decent value, falling into a mid-range compared to extremely cheap and very expensive options. Like most quality SAMe products, it is likely enteric-coated to ensure stability and absorption, though this is not explicitly detailed. Its primary limitation is the 200mg dose, meaning higher therapeutic levels would require multiple tablets, and it does not include the beneficial B vitamin cofactors that some users prefer for enhanced SAMe metabolism.
- Offers a standard 200mg dose of SAMe.
- Natural Factors is a well-established and reputable brand.
- Good price per serving ($0.58) for a 200mg dose, offering decent value.
- Good number of positive online reviews, indicating reliable user satisfaction.
- Only 200mg SAMe per serving, requiring multiple tablets for higher therapeutic doses.
- Does not explicitly specify the stable form of SAMe (e.g., Disulfate Tosylate).
- Does not include additional B vitamin cofactors that could enhance SAMe metabolism.
- Individuals taking antidepressants or other mood-altering medications should consult a healthcare professional before using SAMe due to potential interactions.
$34.97($0.58 per serving)
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bolt Effectiveness for goals
Yes, SAMe can potentially interact with certain medications and other supplements. For instance, it may interact with antidepressants, increasing serotonin levels, or with blood-thinning medications. These interactions could alter its effectiveness or lead to adverse effects, so consulting a healthcare professional is advisable.
SAMe is a compound naturally found in the body and is a key player in several biochemical reactions. Supplementation is most commonly studied for its potential roles in supporting mood balance, joint comfort, and liver health. Its effectiveness stems from its involvement in methylation processes.
SAMe has been extensively researched for its potential effectiveness in supporting mood balance, joint comfort, and liver health. It is a compound naturally occurring in the body, and its supplemental form is used to address deficiencies or enhance metabolic pathways. Scientific interest also extends to its role in various neurological and detoxification processes.
Several studies suggest that SAMe may play a role in supporting a healthy mood and emotional well-being. It is believed to influence the synthesis of neurotransmitters like serotonin and dopamine. While promising, individual responses can vary, and it should not replace prescribed treatments for mood disorders without professional guidance.
Research suggests that SAMe may play a role in supporting mood balance, particularly by influencing neurotransmitter synthesis. Several studies have explored its potential benefits in this area. Individual responses can vary.
schedule Dosage, timing & forms
A common starting dosage for SAMe often ranges from 200-400 mg per day. It is generally recommended to begin with a lower dose and gradually increase it if needed. This approach helps the body adjust and assess individual tolerance.
Many SAMe supplements are enteric-coated to protect the compound from stomach acid degradation. This coating allows the SAMe to pass through the stomach intact and dissolve in the more alkaline environment of the small intestine. This helps ensure better absorption and stability of the ingredient.
Enteric coating is crucial for SAMe because it is sensitive to stomach acid. The coating prevents the SAMe from being degraded in the stomach, allowing it to pass into the small intestine intact. This ensures optimal absorption and bioavailability of the supplement.
SAMe is typically recommended to be taken on an empty stomach, at least 30 minutes before a meal or two hours after. This can help improve its absorption and effectiveness. However, some individuals may take it with a small amount of food to reduce potential stomach upset.
Typical starting dosages for SAMe often range from 200 mg to 400 mg per day. These amounts are sometimes gradually increased based on individual response. Consulting a healthcare provider for personalized guidance is often suggested.
health_and_safety Safety & interactions
Yes, SAMe may interact with antidepressant medications, particularly SSRIs and tricyclic antidepressants. This interaction could potentially increase serotonin levels, raising the risk of serotonin syndrome. It is important to discuss SAMe use with a healthcare provider if taking antidepressants.
Common side effects of SAMe may include nausea, upset stomach, diarrhea, constipation, dry mouth, dizziness, and mild anxiety. These effects are usually mild and may subside with continued use or a lower dose.
Common side effects of SAMe can include gastrointestinal issues such as nausea, diarrhea, and constipation. Some individuals may also experience anxiety, restlessness, or insomnia. These effects are typically mild and often resolve with continued use or a dosage adjustment.
SAMe is contraindicated for individuals with bipolar disorder due to the risk of inducing mania. It should also be used with caution or avoided by those taking antidepressant medications, L-dopa, or blood thinners. Pregnant or breastfeeding women and children should generally avoid SAMe unless advised by a healthcare professional.
Individuals with bipolar disorder should use SAMe with extreme caution and under medical supervision. Pregnant or breastfeeding women, and those with compromised immune systems, are also generally advised against using SAMe due to insufficient safety data. Consulting a healthcare provider is recommended for these groups.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| SAMe | 200 mg |
Categories
SAMe 75.0
As a SAMe product, its reliable brand and good value for a 200mg dose make it a solid choice, particularly for those seeking a balance of quality and affordability without added cofactors.
Goals
Mood Support 80.0
The 200mg dose is a good starting point for mood support, and its reasonable price makes it accessible for daily use, allowing for flexible dose adjustments if needed.
Joint Health 75.0
While 200mg is on the lower side for typical joint support, the product's good value allows for taking multiple doses daily to reach more effective levels (e.g., 400-800mg) for joint health.
Digestive Health 75.0
For liver and digestive health, 200mg serves as a good base. Its cost-effectiveness facilitates consistent daily intake, enabling users to increase amounts if needed for comprehensive support.
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