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Brain Factors

Thorne
4.7
(301 ratings)
Niacin 415 mg
Betaine Anhydrous 85 mg
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Score94

A premium NAD+ precursor supplement designed to support cellular energy and brain vitality.

How scoring works
Quantity:30 Capsule(s)(30 servings)
Goals:
Skin Health
Heart Health
Cardiovascular Support

Score 94

A premium NAD+ precursor supplement designed to support cellular energy and brain vitality.

How scoring works
$51.00($1.70 per serving)
Pure Formulas
$ 51.00
Walmart
$ 51.00
iHerb
$ 51.00
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Analysis

Nicotinamide riboside is a unique form of B3 that helps fuel the mitochondria, the energy centers of your cells. This may contribute to better mental clarity and support heart tissue resilience over time.

The addition of coffee fruit extract and betaine anhydrous helps with brain signaling and healthy homocysteine levels. It is a professional-grade supplement for individuals prioritizing metabolic longevity and brain health.

Pros

  • Uses patented Nicotinamide Riboside
  • Supports mitochondrial energy
  • Includes brain-supporting coffee fruit
  • Vegetarian capsules

Cons

  • Premium price point
  • Only 30 servings per bottle
  • Betaine dose is modest

Warnings

  • Monitor energy levels; may be slightly stimulating
  • Keep out of direct sunlight

Nutrient quality

99 Highest impact

The use of high-purity Nicotinamide Riboside as an advanced NAD+ precursor represents the leading edge of metabolic support. Synergistic pairing with betaine anhydrous supports the body's methylation pathways more effectively during NAD+ elevation.

Ingredient transparency

99 Highest impact

Full label disclosure clearly identifies the primary active ingredients and their respective chemical forms. The use of branded CognatiQ coffee fruit extract demonstrates a high commitment to ingredient specificness and quality transparency.

Customer satisfaction

90 Highest impact

Consistent high ratings reflect a high degree of reliability and consumer trust in this specialized formula. Positive user feedback confirms the product's effectiveness for mental energy and daily focus, justifying its premium design.

Value for money

84 Highest impact

While the price point is premium, it is justified by the use of high-purity Nicotinamide Riboside and specialized CognatiQ extract. Each serving provides significant functional utility for those seeking advanced metabolic and heart support compared to basic options.

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Goals

Impact
Highest effect
B- Goal FitA+ Strength of SupportB- CoverageA Formula Quality

This advanced formula supports cellular repair and antioxidant status through a clinical dose of nicotinamide riboside.

By including coffee fruit extract and betaine, it appears well aligned with general metabolic health that can indirectly support skin vitality.

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Impact
Highest effect
B- Goal FitA- Strength of SupportC+ CoverageA Formula Quality

Brain Factors utilizes Nicotinamide Riboside and Betaine Anhydrous to support cellular energy production and metabolic pathways. Nicotinamide Riboside is an NAD+ precursor that may contribute to mitochondrial efficiency in cardiovascular tissues.

Betaine anhydrous supports the homocysteine cycle, which is important for maintaining healthy vascular function. This supplement appears well aligned for individuals seeking advanced metabolic support that may provide secondary benefits for cardiovascular resilience.

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Impact
High effect
B Goal FitB Strength of SupportC+ CoverageA+ Formula Quality

This formulation combines Nicotinamide Riboside and Betaine, which provide metabolic and homocysteine support relevant to cardiovascular health. Nicotinamide Riboside serves as an advanced precursor to NAD+, potentially supporting vascular vitality and mitochondrial function.

While the product is primarily positioned for cognitive support, the ingredients touch on important cardiovascular mechanisms. The dosage of NR is consistent with clinical research, though the betaine dose is modest for significant homocysteine management.

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Ingredients

IngredientAmount per serving
Nicotinamide Riboside Hydrogen Malate
415 mg
CognatiQ (Coffee Fruit Extract)
100 mg
Betaine Anhydrous
85 mg
Gluten Free Adults 18–50
Report overview
Niacin · 415 mg OverallScore88
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
Thorne Brain Factors uses a patented NAD+ precursor to support cognitive function and cellular metabolism. This advanced formula provides high-quality, bioavailable ingredients for cellular energy.
Betaine Anhydrous · 85 mg OverallScore87
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB Value
This brain-support supplement includes betaine anhydrous to complement nicotinamide riboside in supporting NAD+ levels. It is a premium option for those focused on cognitive longevity and cellular energy.
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