L-Arginine L-Citrulline Complex
Source Naturals
L-Arginine L-Citrulline Complex
4.5
★ ★ ★ ★ ★
(3852 ratings)
Citrulline 250 mg
Arginine 750 mg
Score 80.0
A combined L-Arginine (in HCl form) and L-Citrulline supplement from Source Naturals, targeting nitric oxide production, with a slightly higher arginine dose per tablet but requiring multiple servings for full efficacy.
Quantity: 120 Tablet(s)Servings size: 1 Tablet(s) (120 servings)
Selected goals:
Other goals:
Fitness
Muscle Gain
Cardiovascular Support
Heart Health
leaderboard Score 80.0
A combined L-Arginine (in HCl form) and L-Citrulline supplement from Source Naturals, targeting nitric oxide production, with a slightly higher arginine dose per tablet but requiring multiple servings for full efficacy.
insights Analysis
This Source Naturals product offers a combination of L-Arginine Hydrochloride (750mg) and L-Citrulline (250mg) per serving, alongside a minimal calorie count. The inclusion of L-Arginine HCl is notable as it is a common and generally well-absorbed form of arginine. Similar to other supplements in this category, it aims to boost nitric oxide levels for improved blood flow, muscle pump, and cardiovascular health. While the L-Arginine dose is slightly higher than the NOW Sports options per serving, the L-Citrulline dose remains quite low, and overall, multiple tablets would still be required to achieve dosages typically associated with significant benefits in fitness or cardiovascular research. It's a reliable option, but not the most economical for higher dosages.
- Contains L-Arginine in the Hydrochloride (HCl) form, which is generally considered well-absorbed, potentially enhancing its effectiveness.
- Provides a slightly higher dose of L-Arginine per serving (750mg) compared to some standard arginine supplements, offering more of this key amino acid per pill.
- Source Naturals is a respected brand in the supplement industry, known for its commitment to quality and comprehensive formulations.
- The dosage of L-Citrulline (250mg) is quite low, and even the 750mg of L-Arginine HCl would require multiple tablets to reach clinically effective levels for many individuals, similar to other capsule products.
- At $0.15 per serving, it's less cost-effective than the larger 240-count NOW Sports product, especially when factoring in the need for multiple servings to achieve desired physiological benefits.
- Individuals with low blood pressure or those taking blood pressure medications should consult a healthcare professional, as L-Arginine and L-Citrulline can affect blood pressure.
- Consult a doctor before use if you have any pre-existing medical conditions, are pregnant or nursing, or are on any other medications, especially those for cardiovascular conditions or erectile dysfunction.
- People prone to herpes outbreaks should be cautious due to arginine's potential impact on viral replication.
$16.37($0.13 per serving)
 iHerb | $ 16.37 | |
 Amazon | $ 18.18 | |
 Pure Formulas | $ 18.19 | |
 Vitacost | $ 18.19 |
bolt Effectiveness for goals
Yes, L-Citrulline supplementation can lead to higher and more sustained plasma L-Arginine levels than Arginine supplementation alone. This is because Citrulline bypasses intestinal and liver metabolism, being efficiently converted to Arginine in the kidneys. This indirect pathway can more effectively increase nitric oxide production.
L-Citrulline is often considered more effective at increasing sustained L-Arginine and nitric oxide levels in the body than L-Arginine itself. This is because L-Citrulline bypasses significant metabolism in the gut and liver, converting to L-Arginine more efficiently in the kidneys. This leads to a more pronounced and prolonged increase in circulating L-Arginine.
L-Citrulline is converted to L-Arginine in the kidneys, which then increases nitric oxide production. This can lead to enhanced blood flow to muscles during exercise, potentially reducing fatigue and improving endurance. It's particularly studied for high-intensity activities and resistance training.
Combining L-Arginine and L-Citrulline may offer enhanced and more sustained nitric oxide production. L-Citrulline can recycle back into L-Arginine, creating a continuous supply for nitric oxide synthesis. This combined approach could potentially lead to greater and longer-lasting effects on blood flow compared to taking either supplement alone.
L-Citrulline is converted to L-Arginine in the body, leading to increased nitric oxide production. This can help improve blood flow to muscles during exercise, potentially enhancing endurance and reducing fatigue. Studies have shown L-Citrulline to be effective in improving performance in both aerobic and anaerobic exercises.
schedule Dosage, timing & forms
Yes, Arginine and Citrulline can be taken together, and some individuals choose to combine them. Citrulline is converted to Arginine in the body, which can effectively increase Arginine levels. Taking them together may offer a synergistic approach, potentially providing both immediate and sustained benefits.
Citrulline is generally considered more effective at increasing and sustaining blood Arginine levels when taken orally. This is because Arginine itself undergoes significant breakdown in the gut and liver (first-pass metabolism) before reaching systemic circulation. Citrulline bypasses this metabolism and is efficiently converted to Arginine in the kidneys.
For exercise performance, dosages of L-Citrulline typically range from 6 to 8 grams per day. If using Citrulline Malate (often a 2:1 ratio of Citrulline to Malate), a common dose is 8 to 12 grams, providing an equivalent amount of L-Citrulline. For general cardiovascular support, lower doses around 3-4 grams may be suggested.
For exercise performance, typical dosages are 6 to 8 grams of L-Citrulline, or 8 to 12 grams of Citrulline Malate. Citrulline Malate is often a 2:1 ratio (6-8g L-Citrulline). It's generally recommended to take it about 60 minutes before physical activity.
When combining them, it's generally recommended to start with conservative doses for each. Since Citrulline effectively raises Arginine levels, you might consider slightly lower individual Arginine doses than if taking it alone. Monitoring your body's response is key to finding the optimal combined dosage.
health_and_safety Safety & interactions
Yes, L-Arginine and L-Citrulline can generally be taken together. L-Citrulline is a precursor to L-Arginine, and combining them may lead to sustained increases in nitric oxide levels. However, potential additive effects on blood pressure should be considered.
Yes, L-Arginine can interact with medications for blood pressure, erectile dysfunction (e.g., sildenafil), and nitrates, potentially causing blood pressure to drop too low. It may also interact with blood thinners and diabetes medications. Consulting a healthcare professional is crucial, especially if taking other medications.
Common side effects of L-Arginine can include abdominal pain, bloating, diarrhea, and nausea, especially at higher doses. These effects are generally mild and temporary. Individuals may also experience a drop in blood pressure.
L-Citrulline is generally well-tolerated, but some individuals may experience mild gastrointestinal discomfort, such as nausea or diarrhea. These side effects are more likely at higher doses. It can also potentially lower blood pressure.
Yes, L-Arginine can interact with medications for high blood pressure. Because L-Arginine can lower blood pressure, taking it with antihypertensive drugs might cause blood pressure to drop too low. It is advisable to consult a healthcare professional before combining them.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Calories | 5 Calorie(s) |
L-Arginine | 750 mg |
L-Citrulline | 250 mg |
Categories
Arginine 78.0
Offers 750mg of L-Arginine HCl per serving, which is a readily absorbed form of arginine and a decent dose per pill for foundational support. However, higher daily doses would be necessary to maximize its benefits, and the price point is less competitive for such an intake.
Citrulline 75.0
Contains L-Citrulline, which effectively boosts L-Arginine levels for nitric oxide production. However, the 250mg dosage per tablet is on the lower side for standalone citrulline effects, meaning multiple tablets are needed to achieve more pronounced benefits.
Goals
Fitness 80.0
This product combines L-Arginine HCl and L-Citrulline, ingredients known to support blood flow and athletic performance. While the per-capsule dosage is modest, users can take multiple tablets to leverage the benefits for enhanced endurance and muscle pump during workouts.
By providing precursors to nitric oxide, this supplement can aid in maintaining healthy vascular tone and blood pressure. The presence of L-Arginine HCl is a good feature, though higher doses through multiple tablets would be needed for optimal cardiovascular support.
Muscle Gain 78.0
While L-Arginine and L-Citrulline can aid in nutrient delivery to muscles and support the 'pump' sensation, the limited per-serving dosage means its direct impact on muscle gain would be minimal without taking several tablets, making it less practical for this goal.
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