L-Methylfolate 15 mg
MethylPro
Score 65
An exceptionally high-dose L-Methylfolate capsule for intensive methylation and mood support, with a complementary glycine dose, requiring professional guidance.
Score 65
An exceptionally high-dose L-Methylfolate capsule for intensive methylation and mood support, with a complementary glycine dose, requiring professional guidance.
Analysis
This MethylPro product provides an extremely high 15 mg dose of L-Methylfolate, the active form of folate, alongside 250 mg of glycine in capsule form. This is a highly specialized formulation for individuals with profound needs for active folate to support critical methylation pathways, neurological function, and severe mood imbalances.
The glycine content is a complementary addition, offering supportive roles in neurotransmission and detoxification, making this a potent product requiring careful consideration and professional guidance due to its very high L-Methylfolate concentration.
Pros
- Provides an extremely high 15mg dose of L-Methylfolate, suitable for very specific and high-level needs.
- Includes a supportive amount of glycine for additional benefits.
- From a brand specialized in methylation support.
- 90 servings per bottle, offering a substantial supply for its niche.
Cons
- Very high price per serving, reflecting the specialized and potent dosage.
- Glycine dose (250mg) is minor and secondary to L-Methylfolate's primary role.
- This dose of L-Methylfolate is not for general use and *must* be under professional supervision.
- Lower review count (73) for a product of this specialization, although more than other MethylPro products.
Warnings
- CRITICAL WARNING: This very high dose of L-Methylfolate should *only* be used under the direct supervision and recommendation of a qualified healthcare professional.
- High folate intake can mask or worsen symptoms of Vitamin B12 deficiency; ensure B12 status is thoroughly evaluated by a doctor.
- May interact with numerous medications, including anticonvulsants, antidepressants, and chemotherapy drugs; always consult your doctor or pharmacist.
- Monitor for potential side effects such as agitation, anxiety, or sleep disturbances, especially when initiating, and report to a healthcare professional.
$75.00($0.83 per serving)
 Pure Formulas | $ 75.00 | |
 Walmart | $ 75.00 |
Goals
Impact
Highest effect
This exceptionally high dose of L-Methylfolate is designed for intensive support of neurotransmitter synthesis and mood regulation, making it highly impactful for specific mood challenges under professional care.
Impact
Highest effect
While highly specialized, the profound impact on methylation pathways contributes significantly to fundamental cellular and metabolic health for those who specifically require it under clinical supervision.
Impact
High effect
The extremely high dose of L-Methylfolate provides intensive support for methylation pathways critical to detoxification, with glycine offering additional complementary assistance.
Impact
High effect
By providing intensive support for mood and neurological balance, it may help in managing severe stress, but requires careful monitoring and professional guidance.
Impact
High effect
Intensive methylation support (L-Methylfolate) and general cellular support (glycine) contribute to fundamental healthy aging processes at a metabolic level.
Impact
Moderate effect
The glycine offers some relaxation, but the overwhelming focus is on high-dose folate, which is not primarily for sleep and could even be stimulating in some individuals.
Impact
Moderate effect
Glycine can support the gut lining, but the product's main purpose is not digestive health, making this a secondary benefit.
Impact
Moderate effect
Folate may indirectly influence inflammatory pathways, but it's a minor aspect of this product's primary action, which is methylation support.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Folate | 25 mg DFE |
Glycine | 250 mg |
Glycine 58
Glycine is present at 250mg, but it is a minor, supportive ingredient within a product overwhelmingly focused on a very high dose of L-Methylfolate for specific clinical needs.
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Though a broader multivitamin, it provides 610mg of Glycine and 333mcg DFE of Folate, along with essential vitamins and minerals. This offers a comprehensive and good value option for foundational health support with both key ingredients present.
92 Value
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While the price per serving is higher, the robust combination of NAC and Glycine offers superior targeted support for detoxification and cellular health, making it a strong value proposition for these specific goals, complementing the methylation support of folate.
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Glycine Powder
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While slightly lower in price per serving, this Glycine powder delivers a massive 4000mg dose. This can provide significantly more profound support for detoxification, mood, and sleep, complementing the benefits of active folate if taken separately.
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This powerful duo provides 1800mg of both Glycine and N-Acetyl-L-Cysteine. These two ingredients are paramount for glutathione synthesis, offering a highly targeted and robust approach to detoxification and antioxidant defense, which is synergistic with folate's metabolic roles.
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Advanced Magnesium Complex
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This product includes a substantial 1440mg of Glycine (as Magnesium Glycinate) along with various forms of Magnesium. Magnesium is crucial for numerous metabolic processes, including those impacting mood and energy, offering comprehensive support alongside Glycine's benefits.