Product Image

5-HTP 100 mg

Metabolic Maintenance
4.7
★ ★ ★ ★ ★
(124 ratings)
5-HTP 100 mg
Glycine 300 mg
Product Image
Score95

A long-term supply of mood and sleep support using a clean blend of 5-HTP, glycine, and cofactors.

How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Mood Support
Sleep Support
Stress Relief
Weight Loss

Score 95

A long-term supply of mood and sleep support using a clean blend of 5-HTP, glycine, and cofactors.

How scoring works

Also available as

1 option
60 servings Glycine 440 mg, 5-HTP 100 mg • 60 Capsule(s) • 60 servings $36.00 ($0.60 per serving)
$46.00($0.38 per serving)
Pure Formulas
$ 46.00
iHerb
$ 46.00
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Analysis

This formula combines the serotonin precursor 5-HTP with calming glycine and the necessary vitamins to support their metabolism. The larger capsule count makes it a practical choice for maintaining a steady mood and supporting restful sleep over several months.

The high-purity standards of Metabolic Maintenance ensure that you are getting a clean supplement with meaningful doses of each active ingredient. This is a great tool for individuals looking for a balanced approach to managing daily stress and nighttime relaxation.

Pros

  • Convenient 120-count size
  • Balanced amino acid synergy
  • Includes B6 and C for conversion
  • Hypoallergenic and high purity

Cons

  • Significant upfront cost
  • Dose of glycine is lower than some
  • Requires consistent daily use

Warnings

  • Do not use with prescription antidepressants
  • May cause sleepiness if taken during day
  • Monitor for mild nausea

Nutrient quality

94 Highest impact

Vitamin B6 and vitamin C are included to facilitate neurotransmitter synthesis and provide antioxidant support. The glycine dose is meaningfully concentrated to enhance the formula's calming synergistic effects.

Ingredient transparency

100 Highest impact

Dosages for all active components are clearly listed, allowing for precise clinical assessment. transparency is further supported by the specific naming of nutrient forms and the absence of proprietary complexes.

Customer satisfaction

93 Highest impact

Consistent ratings and positive user feedback demonstrate broad consumer confidence and efficacy. Users frequently mention success with mood stability and restful sleep without significant side effects.

Value for money

91 Highest impact

The larger bottle count provides improved value per dose compared to smaller sizes. Pricing reflects the professional standards of the brand and the high quality of the active ingredients provided.

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Goals

Mood Support
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageA+ Formula Quality

5-HTP (100mg) and Glycine (300mg) with Vitamin B6.

Providing a direct precursor to serotonin alongside its necessary cofactor supports balanced mood and emotional stability.

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Sleep Support
Impact
Highest effect
A Goal FitB+ Strength of SupportB+ CoverageA+ Formula Quality

5-HTP and Glycine are included to provide a synergistic approach to sleep and relaxation.

Providing 100mg of 5-HTP supports the precursor pathway to melatonin while glycine assists in calming the nervous system.

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Stress Relief
Impact
Highest effect
B+ Goal FitA Strength of SupportB CoverageA+ Formula Quality

Features 5-HTP alongside Glycine, Vitamin C, and Vitamin B6 to support serotonin production and relaxation. This targeted approach appears well aligned with mood stability and emotional stress relief.

The 100 mg dose of 5-HTP is a standard starting point for effectiveness, and Glycine provides additional inhibitory support. High-purity sourcing from a practitioner-grade brand enhances the overall quality profile.

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Weight Loss
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC+ CoverageA Formula Quality

Serotonin-mediated satiety is supported by a standardized dose of 5-HTP, which may contribute to reduced carbohydrate cravings. Synergistic vitamins B6 and C are included to facilitate the biological conversion of the amino acid.

5-Hydroxytryptophan and vitamin B6 are the central active components for appetite management. These ingredients appear well-aligned for those seeking to manage hunger during weight loss.

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Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 100 mg
Vitamin B6
3 mg
5-Hydroxytryptophan
100 mg
Glycine
300 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
5-HTP · 100 mg OverallScore74
C- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
A professional-grade 5-HTP supplement that includes synergistic vitamins and amino acids for enhanced effectiveness. While highly transparent, the lack of botanical source identification and higher price are notable drawbacks.
View ingredientView products
Glycine · 300 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB- Value
This clean 5-HTP formula provides 300 mg of glycine to support mood and relaxation. It is a high-purity, larger count option for daily use.
View ingredientView products
94 Value

5-HTP 100 mg

Metabolic Maintenance
4.7
★★★★★
(122 ratings)
This smaller size provides the same high-purity 5-HTP and glycine formula for those who prefer to test the product first. It maintains a clean, additive-free approach to supporting daily stress management.
Other sellers (0)
96 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
★★★★★
(7340 ratings)
With an excellent overall score, this 100 mg dose offers clinical-standard support for serotonin synthesis. It represents great value for a high-quality botanical extract focused on mood stabilization.
Other sellers (2)
95 Value

Glycine 500 mg

Solgar
4.8
★★★★★
(2875 ratings)
A pure, single-ingredient capsule format allows for precise titration in a plan for metabolic support. It offers a very reliable and cost-effective source of inhibitory neurotransmitter support.
Other sellers (4)
95 Performance

Advanced Magnesium Complex

AOR Advanced Orthomolecular Research Advanced
4.8
★★★★★
(650 ratings)
This formula delivers a substantial 1,440 mg of glycine via a highly bioavailable magnesium glycinate form. It provides systemic support and efficient mineral delivery that significantly enhances relaxation goals.
Other sellers (2)
96 Performance

5-HTP 200 mg

NutraBio
4.7
★★★★★
(771 ratings)
The 200 mg concentration of 5-HTP offers robust support for mood regulation and evening tranquility. It is perfectly calibrated for individuals who need a stronger dose of this neurotransmitter precursor.
Other sellers (1)
93 Performance

5-HTP 200 mg Time Release

Natrol
4.5
★★★★★
(7969 ratings)
Time-release technology maintains steady serotonin levels throughout the day and helps reduce gastrointestinal sensitivity. This advanced delivery method supports long-term emotional stability and well-being.
Other sellers (3)
92 Budget

5-HTP 50 mg

NOW
4.7
★★★★★
(14251 ratings)
A lower 50 mg dose allows for a gentler approach to serotonin support while providing excellent cost savings. It is a practical alternative for those starting a new regimen for mood or rest.
Other sellers (4)
93 Budget

Glycine 500 mg

Country Life
4.9
★★★★★
(3588 ratings)
Combining glycine with vitamin B6 supports metabolic pathways and neurological health at a very accessible price. It provides a baseline dose of a key calming amino acid alongside its essential cofactor.
Other sellers (1)
93 Budget

5-HTP 50 mg

Swanson Premium Brand
4.6
★★★★★
(923 ratings)
This standardized botanical source of 5-HTP provides consistent delivery for emotional balance. It offers a focused pathway for serotonin support that is more budget-friendly for daily use.
Other sellers (1)
94 Value

5-HTP 100 mg

Metabolic Maintenance
4.7
★★★★★
(122 ratings)
This smaller size provides the same high-purity 5-HTP and glycine formula for those who prefer to test the product first. It maintains a clean, additive-free approach to supporting daily stress management.
Other sellers (0)
96 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
★★★★★
(7340 ratings)
With an excellent overall score, this 100 mg dose offers clinical-standard support for serotonin synthesis. It represents great value for a high-quality botanical extract focused on mood stabilization.
Other sellers (2)
95 Value

Glycine 500 mg

Solgar
4.8
★★★★★
(2875 ratings)
A pure, single-ingredient capsule format allows for precise titration in a plan for metabolic support. It offers a very reliable and cost-effective source of inhibitory neurotransmitter support.
Other sellers (4)
95 Performance

Advanced Magnesium Complex

AOR Advanced Orthomolecular Research Advanced
4.8
★★★★★
(650 ratings)
This formula delivers a substantial 1,440 mg of glycine via a highly bioavailable magnesium glycinate form. It provides systemic support and efficient mineral delivery that significantly enhances relaxation goals.
Other sellers (2)
96 Performance

5-HTP 200 mg

NutraBio
4.7
★★★★★
(771 ratings)
The 200 mg concentration of 5-HTP offers robust support for mood regulation and evening tranquility. It is perfectly calibrated for individuals who need a stronger dose of this neurotransmitter precursor.
Other sellers (1)
93 Performance

5-HTP 200 mg Time Release

Natrol
4.5
★★★★★
(7969 ratings)
Time-release technology maintains steady serotonin levels throughout the day and helps reduce gastrointestinal sensitivity. This advanced delivery method supports long-term emotional stability and well-being.
Other sellers (3)
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