B12 1000 mcg
Nature Made
B12 1000 mcg
4.7
★ ★ ★ ★ ★
(27717 ratings)
Vitamin B12 1000 mcg
Score 73.0
A popular and trusted 1000 mcg Cyanocobalamin B12 supplement from a leading brand, offering general B12 support.
Quantity: 160 Tablet(s)Servings size: 1 Tablet(s) (160 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 73.0
A popular and trusted 1000 mcg Cyanocobalamin B12 supplement from a leading brand, offering general B12 support.
insights Analysis
This Nature Made B12 supplement delivers 1000 mcg of Vitamin B12 in the Cyanocobalamin form. Nature Made is a widely recognized and trusted brand, often recommended for its quality control and adherence to standards, which is reflected in its extremely high review count. The 1000 mcg dosage is typical for daily supplementation to prevent deficiency or support general health. While the Cyanocobalamin form is effective for many, it's not the active form preferred by some nutritionists for optimal absorption and benefits, particularly for those with impaired methylation pathways. The price per serving is competitive for a mainstream brand.
- From Nature Made, a highly reputable brand known for quality and purity standards.
- Very high review count indicates broad consumer trust and satisfaction.
- Standard 1000 mcg dosage is effective for general B12 supplementation.
- Uses Cyanocobalamin, a synthetic form of B12 that may not be as readily absorbed or utilized by the body as Methylcobalamin for some individuals.
- Not formulated for specific sublingual absorption, potentially reducing bioavailability compared to quick-dissolve or lozenge forms.
- Price per serving is average, with cheaper alternatives available offering similar formulations.
$10.65($0.06 per serving)
 Amazon | $ 10.65 | |
 Vitacost | $ 16.19 | |
 iHerb | $ 18.49 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B12 | 1000 mcg |
Calcium | 120 mg |
Categories
Vitamin B12 73.0
As a Vitamin B12 supplement, it offers a standard dosage from a trusted brand, making it a solid choice for general supplementation, though the form is not the most advanced.
Goals
Energy 75.0
The 1000mcg dosage adequately supports the body's energy production pathways, making it effective for contributing to sustained energy levels.
Metabolism Boost 75.0
B12 is a key coenzyme in the metabolism of macronutrients. The 1000mcg dose effectively supports these processes, contributing to an overall metabolism boost.
Brain Health 70.0
B12 is essential for nerve health, contributing to brain function. However, the Cyanocobalamin form is not universally considered the most optimal for direct neurological benefits compared to Methylcobalamin.
Recommended Alternatives
92 Value 
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
Offers a highly bioavailable Methylcobalamin form at a strong 1500mcg dose for a competitive price (7 cents per serving), providing exceptional quality for its cost.
85 Value 
B-12 1000 mcg
Nature's Bounty
4.7
★★★★★
(65813 ratings)
Provides the same 1000mcg Cyanocobalamin dose as Nature Made at a lower price per serving (4 cents), offering comparable quality for a better economic value.
88 Value 
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
Delivers a 1000mcg Methylcobalamin (active form) at a reasonable price per serving (8 cents), offering a significant quality upgrade over Cyanocobalamin for a modest increase in cost.
92 Performance
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
Utilizes Methylcobalamin, the active form of B12, at a higher 1500mcg dose, providing superior bioavailability and direct cellular utilization for enhanced benefits compared to Cyanocobalamin.
90 Performance
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
Offers 1000mcg of Methylcobalamin, which is more readily absorbed and utilized by the body for energy and neurological support, making it a more effective choice for many individuals.
90 Performance 
Methyl B-12 1000 mcg Lemon Flavor
Jarrow Formulas
4.7
★★★★★
(11077 ratings)
Delivers Vitamin B12 in the active Methylcobalamin form at the same 1000mcg dose, which is generally considered superior for its direct cellular uptake and efficacy.
85 Budget
B-12 1000 mcg
Nature's Bounty
4.7
★★★★★
(65813 ratings)
Offers an identical 1000mcg dosage of Cyanocobalamin for a lower price per serving (4 cents vs 6 cents), providing a more economical option from a comparable mainstream brand.
80 Budget 
B-12 1000 mcg
21st Century
4.7
★★★★★
(9825 ratings)
Provides 1000mcg of Cyanocobalamin at an even more competitive price per serving (5 cents), making it a budget-friendly alternative for similar B12 supplementation.
78 Budget 
Vitamin B-12 Lozenges 1000 mcg
Swanson Premium Brand
4.7
★★★★★
(817 ratings)
Presents a more affordable option with a price per serving of 5 cents and a convenient lozenge format, delivering a standard dose of Cyanocobalamin.
92 Value
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
Offers a highly bioavailable Methylcobalamin form at a strong 1500mcg dose for a competitive price (7 cents per serving), providing exceptional quality for its cost.
85 Value
B-12 1000 mcg
Nature's Bounty
4.7
★★★★★
(65813 ratings)
Provides the same 1000mcg Cyanocobalamin dose as Nature Made at a lower price per serving (4 cents), offering comparable quality for a better economic value.
88 Value
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
Delivers a 1000mcg Methylcobalamin (active form) at a reasonable price per serving (8 cents), offering a significant quality upgrade over Cyanocobalamin for a modest increase in cost.
92 Performance
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
Utilizes Methylcobalamin, the active form of B12, at a higher 1500mcg dose, providing superior bioavailability and direct cellular utilization for enhanced benefits compared to Cyanocobalamin.
90 Performance
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
Offers 1000mcg of Methylcobalamin, which is more readily absorbed and utilized by the body for energy and neurological support, making it a more effective choice for many individuals.
90 Performance
Methyl B-12 1000 mcg Lemon Flavor
Jarrow Formulas
4.7
★★★★★
(11077 ratings)
Delivers Vitamin B12 in the active Methylcobalamin form at the same 1000mcg dose, which is generally considered superior for its direct cellular uptake and efficacy.