B-6 B-12 Folic Acid Drop Ins Natural Mixed Berry Flavor
KAL
B-6 B-12 Folic Acid Drop Ins Natural Mixed Berry Flavor
4.8
★ ★ ★ ★ ★
(2076 ratings)
Folate 680 mcg
Vitamin B12 2500 mcg
Vitamin B6 10 mg
Score 97.0
This KAL supplement is an excellent choice, providing Vitamin B6, B12, and Folate in their highly bioavailable, active forms (P-5-P, Methylcobalamin, L-Methylfolate) within a convenient liquid drop format, ensuring optimal absorption and efficacy for energy, brain, and mood support.
Quantity: 2 Fluid Ounce(s)Servings size: 1 mL (59 servings)
Selected goals:
Other goals:
General Health
Brain Health
Mood Support
Heart Health
Energy
leaderboard Score 97.0
This KAL supplement is an excellent choice, providing Vitamin B6, B12, and Folate in their highly bioavailable, active forms (P-5-P, Methylcobalamin, L-Methylfolate) within a convenient liquid drop format, ensuring optimal absorption and efficacy for energy, brain, and mood support.
insights Analysis
KAL's B-6 B-12 Folic Acid Drop Ins is a highly effective and well-formulated B-vitamin supplement, specifically targeting three crucial B vitamins known for their roles in energy, brain health, and mood. Its primary strength lies in utilizing the active and most bioavailable forms of each nutrient: Methylcobalamin for B12, (6S)-5-Methyltetrahydrofolate (L-Methylfolate) for Folate, and Pyridoxal 5-Phosphate (P-5-P) for B6. These active forms ensure maximum absorption and direct utilization by the body, bypassing conversion steps that some individuals may struggle with due to genetic variations. The liquid format also offers an advantage for rapid absorption and ease of use, particularly for those who have difficulty swallowing pills or prefer a flexible dosage. Online reviews consistently praise its efficacy for increased energy and mood improvement, aligning with its ingredient profile. While the B12 dose of 2500mcg is significantly higher than daily requirements, it is generally considered safe for a water-soluble vitamin and is often desired by individuals seeking a potent boost.
- Contains highly bioavailable, active forms of Vitamin B6 (P-5-P), Vitamin B12 (Methylcobalamin), and Folate (L-Methylfolate), which are superior to synthetic forms like pyridoxine HCl, cyanocobalamin, and folic acid.
- Liquid drop form allows for flexible dosing and potentially faster absorption, making it suitable for individuals who have difficulty swallowing pills.
- The targeted blend of these specific B vitamins is highly effective for supporting energy production, cognitive function, and mood stability.
- Offers good value per serving given the premium quality and active forms of the B vitamins included.
- The 2500mcg dosage of Vitamin B12 is significantly higher than the average daily requirement and may be considered excessive for some individuals.
- The 'Natural Mixed Berry Flavor' may not be universally appealing to all users.
- Individuals should consult with a healthcare professional before taking high doses of B vitamins, particularly if they have underlying health conditions or are on other medications, to ensure suitability and prevent potential interactions.
$19.19($0.32 per serving)
 iHerb | $ 19.19 | |
 Vitacost | $ 19.19 | |
 Amazon | $ 19.19 |
bolt Effectiveness for goals
These three B vitamins play crucial, interconnected roles in metabolic processes, particularly the methylation cycle. They are essential for converting homocysteine into other beneficial molecules, supporting cardiovascular health. Their combined action helps maintain proper nerve function and DNA synthesis.
Yes, B vitamins are fundamental for cellular energy production, helping the body convert food into usable energy. Vitamin B12, in particular, is vital for red blood cell formation and nervous system function, both of which impact energy levels. While not a stimulant, they support the body's natural energy processes.
Active forms, such as Methylcobalamin for B12 and L-Methylfolate for Folate, are body-ready and do not require conversion by the liver before utilization. This can be particularly beneficial for individuals with genetic variations that affect B vitamin metabolism. They are designed for efficient absorption and immediate use by the body.
L-Methylfolate is the biologically active form of folate, essential for DNA synthesis and repair, and cell division. It is crucial for red blood cell formation and supports amino acid metabolism. This active form is readily available for the body's vital functions, including neurotransmitter synthesis.
Yes, Pyridoxal 5-Phosphate (P5P), the active form of Vitamin B6, is critical for the synthesis of several neurotransmitters, which are chemical messengers in the brain. These neurotransmitters regulate mood, sleep, and cognitive function. It also plays a significant role in maintaining nerve health.
schedule Dosage, timing & forms
B vitamins are water-soluble and can generally be taken at any time of day, often with food to minimize potential stomach upset. Some individuals prefer to take them in the morning for potential energy support. Consistency in timing is often considered more important than the specific time of day.
These B vitamins often work synergistically in various bodily functions, including energy metabolism and nerve health. They are frequently combined in supplements to support overall well-being. This combination is particularly noted for its role in homocysteine metabolism.
Folic acid is a synthetic form of Vitamin B9, while folate is the naturally occurring form. L-Methylfolate, specifically (6S)-5-Methyltetrahydrofolate Glucosamine Salt, is a metabolically active form of folate that the body can use directly without conversion. This form may be preferred by individuals with genetic variations affecting folate metabolism.
Methylcobalamin is one of the two active coenzyme forms of Vitamin B12 available in the body. It is often chosen for supplements because it is readily utilized by the body. This form is particularly involved in brain and nerve health.
P-5-P is the active coenzyme form of Vitamin B6 that the body can use directly. Unlike pyridoxine HCl, which needs to be converted, P-5-P is readily available for various metabolic processes. This direct form may be beneficial for individuals who have difficulty converting other forms of B6.
health_and_safety Safety & interactions
Yes, these B vitamins can interact with certain medications, including some anti-seizure drugs, antibiotics, and chemotherapy agents. Always consult a healthcare professional to discuss potential interactions with your current medications.
While Pyridoxal 5-Phosphate is an active form, excessively high and chronic doses of any B-6 form can lead to neurological symptoms like numbness or tingling. It is important to adhere to recommended dosages unless advised otherwise by a healthcare professional.
Yes, high doses of Folate can sometimes mask the symptoms of a Vitamin B-12 deficiency by improving anemia without addressing the underlying B-12 issue. This could delay diagnosis of B-12 deficiency, which can have neurological consequences if left untreated.
These B vitamins are generally well-tolerated. Some individuals might experience mild digestive upset, skin reactions, or a reddish tint to urine due to B12.
Individuals with chronic health conditions, such as kidney disease or autoimmune disorders, should consult their healthcare provider before using these supplements. A doctor can assess individual needs and potential interactions with existing conditions or treatments.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin B-6 (Pyridoxal 5-Phosphate) | 10 mg |
| Folate (Glucosamine Salt, (6S)-5-Methyltetrahydrofolate) | 680 mcg |
| Vitamin B12 (Methylcobalamin) | 2500 mcg |
Categories
Vitamin B12 98.0
The product features Methylcobalamin, the active and highly bioavailable form of Vitamin B12, which is more readily used by the body than the synthetic Cyanocobalamin found in many other supplements.
Folate 98.0
This supplement contains (6S)-5-Methyltetrahydrofolate (L-Methylfolate), the active and most readily usable form of Folate, which is crucial for individuals who may have difficulty converting synthetic folic acid into its usable form.
Vitamin B6 97.0
The inclusion of Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of Vitamin B6, ensures optimal absorption and direct participation in metabolic processes, offering superior efficacy compared to common pyridoxine HCl forms.
Goals
Energy 98.0
The active forms of B6, B12, and Folate are essential cofactors in the body's energy production pathways, supporting the conversion of food into usable energy. The high dose of Methylcobalamin B12 further enhances its efficacy for energy-boosting purposes, making it highly effective for this goal.
Brain Health 97.0
Vitamin B12 (Methylcobalamin), Folate (L-Methylfolate), and Vitamin B6 (P-5-P) are crucial for neurotransmitter synthesis and maintaining healthy myelin sheaths, which are vital for nerve communication and overall brain function. Their active forms ensure optimal utilization for cognitive support.
Cognitive Support 97.0
As active B vitamins are vital for supporting nerve health, myelin integrity, and efficient neurotransmitter production, this product directly contributes to improved cognitive functions such as memory, focus, and overall mental clarity.
Recommended Alternatives
80 Value 
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
This product offers a balanced approach, featuring the active Methylcobalamin form of B12 along with B6 and Folate (albeit in non-active forms), all at a highly competitive price of $8 per serving. It delivers excellent value by combining quality B12 with other essential B vitamins.
82 Value 
Methyl B-12 1000 mcg Lemon Flavor
Jarrow Formulas
4.7
★★★★★
(11077 ratings)
As a highly-rated product from a reputable brand, this alternative offers a substantial dose of active Methylcobalamin B12 at a very attractive price ($8 per serving). It's an excellent value for those prioritizing the benefits of bioavailable B12.
81 Value 
Chewable Fully Active B12 Chocolate Mint Flavor 1000 mcg
Doctor's Best
4.8
★★★★★
(1635 ratings)
This chewable option provides active Methylcobalamin B12 at a reasonable price of $9 per serving, making it a convenient and effective choice. Its active form and palatable format offer good value, especially for those preferring chewable supplements.
90 Performance 
BioActive Folate & Vitamin B12
Life Extension
4.8
★★★★★
(10004 ratings)
This product contains two of the three primary active forms found in the original (Methylcobalamin B12 and L-5-Methyltetrahydrofolate Folate) at a significantly more reasonable price ($10 per serving). Its dual active formulation makes it a highly effective alternative for comprehensive B12 and Folate support.
88 Performance 
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
For targeted B12 support, this alternative provides a high dose of Methylcobalamin, the active form of Vitamin B12, at a very competitive price ($7 per serving). It's an excellent choice for those specifically seeking the superior bioavailability of active B12.
85 Performance 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
This alternative directly offers Pyridoxal 5-Phosphate (P5P), the active form of Vitamin B6, which is a key, high-quality component of the original product. While it's a single vitamin, it provides a crucial active form at a good value ($8 per serving).
60 Budget 
Folic Acid B6 & B12
Mason Natural
4.8
★★★★★
(2530 ratings)
This alternative offers all three key B vitamins (B6, B12, and Folate) in a single supplement at a significantly lower price point ($6 per serving) compared to the original, making it a much more accessible option for a comprehensive B-complex despite using non-active forms.
58 Budget 
B-50 Complex
21st Century
4.7
★★★★★
(8446 ratings)
Providing a full B-complex including B6, B12, and Folate at a very low price ($8 per serving), this product offers a cost-effective way to get essential B vitamins, although it uses standard, non-active forms for most ingredients. It's a practical choice for budget-conscious consumers.
55 Budget 
B-Complex with Folic Acid plus Vitamin C
Nature's Bounty
4.7
★★★★★
(4261 ratings)
This alternative provides a comprehensive B-complex, including B6, B12, and Folic Acid, along with Vitamin C, at a considerably lower price ($9 per serving). While its B vitamin forms are not active, it offers broad nutritional support and superior value compared to the original product.
80 Value
Vegan B12
DEVA
4.7
★★★★★
(6800 ratings)
This product offers a balanced approach, featuring the active Methylcobalamin form of B12 along with B6 and Folate (albeit in non-active forms), all at a highly competitive price of $8 per serving. It delivers excellent value by combining quality B12 with other essential B vitamins.
82 Value
Methyl B-12 1000 mcg Lemon Flavor
Jarrow Formulas
4.7
★★★★★
(11077 ratings)
As a highly-rated product from a reputable brand, this alternative offers a substantial dose of active Methylcobalamin B12 at a very attractive price ($8 per serving). It's an excellent value for those prioritizing the benefits of bioavailable B12.
81 Value
Chewable Fully Active B12 Chocolate Mint Flavor 1000 mcg
Doctor's Best
4.8
★★★★★
(1635 ratings)
This chewable option provides active Methylcobalamin B12 at a reasonable price of $9 per serving, making it a convenient and effective choice. Its active form and palatable format offer good value, especially for those preferring chewable supplements.
90 Performance
BioActive Folate & Vitamin B12
Life Extension
4.8
★★★★★
(10004 ratings)
This product contains two of the three primary active forms found in the original (Methylcobalamin B12 and L-5-Methyltetrahydrofolate Folate) at a significantly more reasonable price ($10 per serving). Its dual active formulation makes it a highly effective alternative for comprehensive B12 and Folate support.
88 Performance
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
For targeted B12 support, this alternative provides a high dose of Methylcobalamin, the active form of Vitamin B12, at a very competitive price ($7 per serving). It's an excellent choice for those specifically seeking the superior bioavailability of active B12.
85 Performance
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
This alternative directly offers Pyridoxal 5-Phosphate (P5P), the active form of Vitamin B6, which is a key, high-quality component of the original product. While it's a single vitamin, it provides a crucial active form at a good value ($8 per serving).