B-100 Complex with B2 Coenzyme
Nature's Way
B-100 Complex with B2 Coenzyme
4.6
★ ★ ★ ★ ★
(1012 ratings)
Vitamin B6 50 mg
Thiamin 100 mg
Vitamin B5 100 mg
Niacin 100 mg
Choline 25 mg
Riboflavin 100 mg
Vitamin B12 100 mcg
Score 88.0
A high-potency B-100 complex featuring activated B2 and B6 forms, offering superior bioavailability for enhanced energy and neurological support, though B12 and Folate are in standard forms.
Quantity: 100 Capsule(s)Servings size: 1 Capsule(s) (100 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support
leaderboard Score 88.0
A high-potency B-100 complex featuring activated B2 and B6 forms, offering superior bioavailability for enhanced energy and neurological support, though B12 and Folate are in standard forms.
insights Analysis
This Nature's Way B-100 Complex is a strong contender for those seeking higher potency B vitamins, especially due to its inclusion of activated forms for Riboflavin (Riboflavin 5-Phosphate) and Vitamin B6 (Pyridoxal 5-Phosphate). These coenzyme forms are more readily utilized by the body, offering enhanced support for energy, metabolism, and neurological health. It provides 100mg/mcg of most B vitamins, along with a decent dose of Inositol and Choline. Online reviews generally praise its effectiveness for energy and mood. However, similar to many standard B-complexes, it still uses Cyanocobalamin for B12 and does not specify an active Folate form, which could be a drawback for some users looking for fully activated ingredients across the board.
- Offers high 100mg/mcg potencies for most B vitamins.
- Includes activated coenzyme forms for Riboflavin (Riboflavin 5-Phosphate) and Vitamin B6 (P-5-P) for superior absorption and utilization.
- Contains Niacinamide to prevent flushing, a common concern with high niacin doses.
- Provides substantial amounts of Inositol and Choline for additional cognitive and metabolic benefits.
- Uses Cyanocobalamin for B12, which is not the most bioavailable form; methylcobalamin is generally preferred for better absorption.
- Folate form is not explicitly stated as L-Methylfolate, which is the most active and bioavailable form, especially important for individuals with MTHFR gene variations.
- Higher price per serving compared to basic B-complex options, which might not be suitable for all budgets.
- Review count is moderate compared to some mass-market B-complexes, indicating a slightly smaller user base.
- Individuals sensitive to higher B vitamin dosages may still experience mild gastrointestinal upset, although Niacinamide minimizes flushing.
- As with most B-complex supplements, consumption may lead to bright yellow urine, which is a normal indicator of vitamin excretion.
$23.99($0.23 per serving)
 Pure Formulas | $ 23.99 | |
 iHerb | $ 23.99 | |
 Vitacost | $ 23.99 | |
 Walmart | $ 27.49 |
bolt Effectiveness for goals
B vitamins act as coenzymes in numerous metabolic pathways, helping convert carbohydrates, fats, and proteins into usable energy. They are essential for processes like glycolysis, the Krebs cycle, and cellular respiration, which are vital for fueling daily activities and cellular functions.
Coenzyme forms are the metabolically active forms of vitamins, meaning the body can utilize them directly without needing to convert them first. This may offer enhanced bioavailability and efficiency for some individuals, ensuring quicker absorption and utilization in biochemical processes. These forms are readily available for the body's enzymatic reactions.
B vitamins are highly interdependent and work synergistically in many bodily functions rather than in isolation. For example, folate and vitamin B12 are crucial for DNA synthesis and red blood cell formation, while several B vitamins are involved in a chain of reactions for energy metabolism. Their combined presence ensures optimal cellular function.
Choline is essential for neurotransmitter synthesis (like acetylcholine), liver function, and lipid metabolism. Inositol is involved in cell signaling, nerve function, and lipid metabolism. They are often grouped with B vitamins due to their similar metabolic roles and synergistic support for cellular health, particularly in nerve and brain function.
Folate and Vitamin B12 are intimately linked in the one-carbon metabolism cycle, which is vital for DNA synthesis, cell division, and the formation of red blood cells. They also work together to metabolize homocysteine, an amino acid, thereby contributing to cardiovascular health. This interaction is critical for numerous physiological processes.
schedule Dosage, timing & forms
Many individuals prefer to take B vitamins in the morning, often with breakfast. This is because B vitamins can sometimes contribute to energy levels, and taking them later in the day might interfere with sleep for some.
Taking B vitamins with food is often recommended to enhance absorption and minimize the potential for stomach upset. As they are water-soluble, food can help facilitate their uptake into the body.
"B-100" typically indicates that the supplement contains 100 milligrams (mg) of most of the key B vitamins, such as B1, B2, B3, B5, and often B6. It suggests a higher potency formulation compared to standard B vitamin dosages.
Including different forms can offer varied bioavailability and support the body's utilization pathways. For example, Riboflavin 5-Phosphate is an active coenzyme form, which the body might use more directly without needing conversion.
Most B vitamin complexes are designed for once-daily consumption. This helps ensure a consistent supply of these water-soluble vitamins, which are not stored in significant amounts by the body and need regular replenishment.
health_and_safety Safety & interactions
Yes, riboflavin (Vitamin B2), commonly found in B vitamin complexes, can cause urine to turn a bright yellow or orange color. This is a harmless and temporary effect as the body excretes excess vitamin. It indicates the vitamin is being absorbed and processed.
Mild side effects from high-dose B vitamin complexes may include temporary gastrointestinal upset, nausea, or headaches. These reactions are typically transient and often resolve as the body adjusts or if the dosage is reduced. More severe side effects are generally rare with standard supplementation.
The niacin in this B complex is in the form of Niacinamide, which is generally not associated with the skin flushing sensation caused by nicotinic acid (another form of niacin). Therefore, flushing is typically not expected with this specific formulation. If flushing occurs, it might be due to other factors or sensitivities.
Yes, folate can interact with certain medications, such as methotrexate, potentially reducing its effectiveness. Vitamin B6 may also interact with levodopa, used for Parkinson's disease. It is advisable to consult a healthcare provider regarding interactions with any prescription drugs to ensure safety and efficacy.
Most B vitamins are water-soluble, meaning excess amounts are typically excreted, reducing the risk of accumulation. However, very high, prolonged intake of certain B vitamins, such as B6, could potentially lead to adverse effects in some individuals. Regular consultation with a healthcare provider is recommended for ongoing long-term use.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Thiamine | 100 mg |
Riboflavin | 100 mg |
Niacin | 100 mg |
Vitamin B6 | 50 mg |
Folate | 666 mcg DFE |
Vitamin B12 | 100 mcg |
Biotin | 100 mcg |
Pantothenic Acid | 100 mg |
Choline | 25 mg |
Inositol | 100 mg |
Categories
Niacin 90.0
Provides 100mg of Niacin as Niacinamide, a high and effective dose that supports energy metabolism and cholesterol health without causing the common 'niacin flush'.
Thiamin 90.0
Delivers a robust 100mg of Thiamine (Vitamin B1), which is excellent for supporting carbohydrate metabolism, nerve function, and overall energy production.
Vitamin B6 90.0
Includes both Pyridoxine Hydrochloride (50mg) and the more bioavailable Pyridoxal 5-Phosphate (50mg), providing comprehensive support for neurotransmitter synthesis and protein metabolism.
Goals
Energy 90.0
With 100mg/mcg of most B vitamins and activated forms of Riboflavin and B6, this product provides potent support for energy production, as these vitamins are directly involved in converting food into cellular energy.
Brain Health 90.0
The inclusion of Pyridoxal 5-Phosphate (activated B6) and high doses of Inositol and Choline, combined with a comprehensive B-vitamin profile, offers robust support for neurotransmitter synthesis and overall neurological function.
Mood Support 90.0
The high potency of B vitamins, especially activated B6 vital for serotonin and dopamine production, along with choline and inositol, significantly contributes to balancing brain chemistry for improved mood regulation.
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