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MK-7 Vitamin K-2 100 mcg

NOW
4.8
★ ★ ★ ★ ★
(31134 ratings)
Vitamin K 100 mcg
Product Image
Score87
A well-dosed, economical MK-7 capsule is highly practical for focused K2 use, though source verification and delivery could be better.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Heart Health
General Health
Bone Health
Cardiovascular Support
Anti-Aging

Score 87

A well-dosed, economical MK-7 capsule is highly practical for focused K2 use, though source verification and delivery could be better.
How scoring works

Also available as

2 options
60 servings K 100 mcg • 60 Capsule(s) • 60 servings $7.00 ($0.11 per serving) 300 mcg • 60 Capsule(s) servings K 300 mcg • 60 Capsule(s) • 60 servings $20.30 ($0.33 per serving)
$19.93($0.16 per serving)
Daily Vita
$ 23.10
Vitacost
$ 19.93
iHerb
$ 20.79
Report prices

Analysis

The 100 mcg serving uses menaquinone-7, a long-acting K2 form suited to daily use. The amount is substantial enough for focused calcium-handling support without the excess of very high-dose products.

The single-active formula is transparent and economical. No branded or verified all-trans source is listed, and the dry capsule supplies no inherent lipid carrier.

It is a strong fit for people who want K2 alone and cover vitamin D and minerals elsewhere. The narrow design should not be mistaken for complete bone or cardiovascular nutrition.

Who is it for
  • Adults seeking a useful daily MK-7 amount
  • Value-conscious long-term users
  • People who prefer a single-active formula
Best for
  • Focused vitamin K2 supplementation
  • Daily calcium-handling support
  • High serving value

Pros

  • Supplies 100 mcg of MK-7
  • Clearly states form and amount
  • Simple one-active formula
  • Excellent serving value

Cons

  • Dry-capsule delivery gives no built-in fat source for this fat-soluble nutrient
  • The supplied label does not identify a branded or verified all-trans MK-7 source
  • No complementary vitamin D3
  • Covers calcium handling but not the wider range of bone or cardiovascular pathways

Warnings

  • Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants; use requires prescriber-guided consistency.
  • Bile-acid sequestrants such as cholestyramine can reduce absorption of fat-soluble vitamin K; follow medication-specific spacing advice.
  • Fat-malabsorption conditions can make vitamin K uptake unreliable, so response may need clinical monitoring.

Nutrient quality

94 Highest impact

A well-regarded form and meaningful amount create a focused supplement. The dose is substantial without being unnecessarily aggressive.

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Ingredient transparency

84 Highest impact

The active form and amount are exceptionally clear with no hidden blend. Missing intake directions and capsule excipients are the only notable gaps.

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Customer satisfaction

73 High impact

Aggregate satisfaction is very strong and supported by an extensive evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment cannot be checked.

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Value for money

97 Highest impact

High-quality forms and a favorable serving position create strong value. The package compares very well with similar vitamin K products.

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Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 vitamin K supports calcium placement and offers a clear arterial-health mechanism. The identified long-acting form is well aligned with cardiovascular use.

The single-active formula is narrow but supplies a meaningful, transparent amount. People using warfarin or another vitamin K antagonist need consistent vitamin K intake because abrupt changes can alter anticoagulant control.

Study evidence
Vitamin K Mixed 62 studies
General Health
General Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA Formula Quality
Vitamin K · 100 mcg

Vitamin K2 is a foundational nutrient for normal calcium handling and supports bone and cardiovascular health. The MK-7 form is well aligned with long-term daily supplementation.

The single active is clearly identified at a useful amount, making the formula easy to assess. Its focused design offers depth rather than broad nutritional coverage, and people using vitamin K antagonist medicines need clinician-guided intake because K2 can counter their effect.

Study evidence
Vitamin K Supportive 34 studies
Bone Health
Bone Health
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageB+ Formula Quality
Vitamin K · 100 mcg

MK-7 provides targeted support for vitamin K-dependent proteins involved in bone mineral use. Its role is relevant and supported by established biological evidence.

The clearly disclosed amount appears meaningful and uses a specific, longer-lasting vitamin K2 form. No calcium, vitamin D, magnesium, or matrix-building nutrient is included, which sharply limits pathway coverage.

Study evidence
Vitamin K Supportive 78 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 is the long-lasting vitamin K2 form used to activate proteins that regulate calcium placement. The clearly disclosed amount is well aligned with arterial-health support, although clinical outcome evidence is less established than for some core cardiovascular nutrients.

The focused formula provides depth in one calcium-management pathway rather than broad heart support. Vitamin K2 can oppose warfarin and related vitamin K antagonists, making stable intake and prescriber guidance important for users of those medicines.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 supports bone proteins and helps manage where calcium is deposited, which is relevant to structural and cardiovascular aging. Evidence is stronger for calcium-regulation markers than for broad healthspan outcomes.

The 100 mcg amount and menaquinone-7 subtype are clearly disclosed in a focused formula. MK-7 can oppose warfarin and other vitamin-K-antagonist anticoagulants, making stable intake and prescriber guidance essential.

Study evidence
Vitamin K Supportive 27 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
 100 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Vitamin K (Menaquinone-7) · 100 mcg OverallScore87
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The 100 mcg MK-7 serving is well aligned with bone and cardiovascular support. A generic source and dry capsule are the main formulation limitations. Very low serving cost makes it highly efficient.

View ingredientView products
Loading alternative details
86 Performance

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
Compared with 100 mcg of MK-7 vitamin K2, the alternative provides 90 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
Compared with 100 mcg of MK-7 vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants.
87 Performance

Vitamin K2 100 mcg

SR Sports Research
Compared with 100 mcg of MK-7 vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants, so intake changes require prescriber guidance.
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
The supplied serving cost is lower, while the formula provides 100 mcg of MK-7 vitamin K2. Vitamin K2 can interfere with warfarin-type anticoagulants.
86 Budget

Liquid D-3 & MK-7

NOW
The supplied serving cost is lower, while the formula provides 62.5 mcg of vitamin D3 with 100 mcg of MK-7 vitamin K2. Its vitamin K can oppose warfarin and related vitamin-K-antagonist anticoagulants, while vitamin D should be considered alongside other supplemental sources.
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
The supplied serving cost is lower, while the formula provides vitamin k2. Its vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake.
87 Value

Low Dose Vitamin K2 (MK-7) 45 mcg

Life Extension
45 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower. Its focused formula offers good routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
86 Value

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
90 mcg of MK-7 vitamin K2 offers a practical value trade-off because the ingredient profile remains focused for the same Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
86 Value

Natural Vitamin K2 MK-7 with MenaQ7 100 mcg

Doctor's Best
100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the ingredient profile remains focused for the same Vitamin K collection. Its vitamin K can oppose warfarin and related vitamin-K-antagonist anticoagulants, so the product is not suitable for unsupervised use with those medicines.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association of vitamin K with cardiovascular events and all-cause mortality: a systematic review and meta-analysis.
    Chen HG; Sheng LT; Zhang YB; Cao AL; Lai YW; Kunutsor SK; Jiang L; Pan A · European journal of nutrition · 2020
    Meta-analysis222,592 participants21 studies pooledHeart Health Cardiovascular Support forVitamin K
  2. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  3. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  4. Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial.
    Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB · Journal of the American Society of Nephrology : JASN · 2021
    Randomized trial159 participantsHeart Health forVitamin K
  5. The relationship between vitamin K and peripheral arterial disease.
    Vissers LET; Dalmeijer GW; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Atherosclerosis · 2017
    Cohort study36,629 participantsCardiovascular Support forVitamin K
  6. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  7. Six weeks phylloquinone supplementation produces undesirable effects on blood lipids with no changes in inflammatory and fibrinolytic markers in postmenopausal women.
    Kristensen M; Kudsk J; Bügel S · European journal of nutrition · 2008
    Randomized trial31 participantsHeart Health forVitamin K
  8. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  9. Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial.
    Cheung AM; Tile L; Lee Y; Tomlinson G; Hawker G; Scher J; Hu H; Vieth R; Thompson L; Jamal S; Josse R · PLoS medicine · 2009
    Randomized trial440 participantsBone Health forVitamin K
  10. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  11. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  12. Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials.
    Vlasschaert C; Goss CJ; Pilkey NG; McKeown S; Holden RM · Nutrients · 2021
    Systematic review9 studies pooledHeart Health forVitamin K
  13. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  14. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsHeart Health Cardiovascular Support forVitamin K
  15. Vitamin K intake and all-cause and cause specific mortality.
    Zwakenberg SR; den Braver NR; Engelen AIP; Feskens EJM; Vermeer C; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Clinical nutrition (Edinburgh, Scotland) · 2018
    Cohort study33,289 participantsHeart Health forVitamin K
  16. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  17. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  20. Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
    Rønn SH; Harsløf T; Pedersen SB; Langdahl BL · European journal of endocrinology · 2017
    Randomized trial148 participantsBone Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsHeart Health Cardiovascular Support forVitamin K
  22. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  23. Dietary vitamin K intakes and atherosclerotic cardiovascular disease incidence: Findings from the UK biobank.
    Dupuy M; Li C; Pokharel P; Zhong L; Parmenter BH; Radavelli-Bagatini S; Dalla Via J; Linneberg A; Jakobsen J; Kühn T; Cassidy A; Hodgson JM; Lewis JR; Sim M; Bondonno NP · Atherosclerosis · 2026
    Cohort study112,111 participantsHeart Health forVitamin K
  24. Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women.
    Bolton-Smith C; McMurdo ME; Paterson CR; Mole PA; Harvey JM; Fenton ST; Prynne CJ; Mishra GD; Shearer MJ · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2007
    Randomized trial244 participantsBone Health forVitamin K
  25. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  26. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  27. Vitamin K1 and progression of cardiovascular calcifications in hemodialysis patients: the VitaVasK randomized controlled trial.
    Saritas T; Reinartz S; Krüger T; Ketteler M; Liangos O; Labriola L; Stenvinkel P; Kopp C; Westenfeld R; Evenepoel P; Siepmann R; Wied S; Hilgers RD; Schurgers L; Floege J; VitaVasK Investigators · Clinical kidney journal · 2026
    Randomized trial60 participantsCardiovascular Support forVitamin K
  28. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  29. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  30. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  31. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  32. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  33. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  34. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  35. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  36. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  37. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K