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Ultra-Zyme

Natures Plus
4.8
★ ★ ★ ★ ★
(1675 ratings)
Glutamic Acid 200 mg
Papain 65 mg
Bromelain 100 mg
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Score93

A high-potency multi-enzyme blend that supports protein, fat, and carbohydrate digestion.

How scoring works
Quantity:180 Tablet(s) • (90 servings)
Goals:

Score 93

A high-potency multi-enzyme blend that supports protein, fat, and carbohydrate digestion.

How scoring works
$36.99($0.41 per serving)
Pure Formulas
$ 37.36
iHerb
$ 37.36
Amazon
$ 36.99
Vitacost
$ 37.36
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Analysis

This formula uses bromelain, papain, and pepsin to help the body break down proteins, while pancreatin and ox bile assist with fats and carbohydrates. It also includes glutamic acid, which may help support a healthy stomach environment for digestion.

The addition of three types of acidophilus supports a balanced intestinal environment after the food is processed. This tablet is well-suited for individuals who experience discomfort after large meals and need broad enzymatic support.

Pros

  • High enzyme activity levels
  • Includes ox bile for fats
  • Supports protein breakdown
  • Contains probiotics
  • Good value for 180 tablets

Cons

  • Not suitable for vegetarians (ox bile/pepsin)
  • May have an odor

Warnings

  • Consult a professional if you have ulcers
  • Do not take on an empty stomach

Nutrient quality

93 Highest impact

High-potency enzymes like Pancreatin 4x and Glutamic Acid provide robust support for digestive processes. The inclusion of Ox Bile and specialized enzymes like Cellulase ensures a comprehensive approach to macronutrient breakdown.

Ingredient transparency

95 Highest impact

Clear labeling of enzyme activity and ingredient amounts allows for an accurate evaluation of the formula strength. Specific weights are provided for all major components, ensuring transparency for the end user.

Customer satisfaction

94 Highest impact

Exceptional average ratings and a high volume of reviews suggest consistent results for those needing intensive digestive support. Feedback specifically highlights the supplement's effectiveness with larger or more difficult-to-digest meals.

Value for money

90 Highest impact

While the total price is higher than basic enzymes, the quantity of servings and potency of the ingredients provide strong value. It compares favorably to other professional-grade enzyme blends on the market due to its comprehensive profile.

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Ingredients

IngredientAmount per serving
Pancreatin 4x
325 mg
Glutamic Acid
200 mg
Acidophilus (Bifidus, Bulgaricus, Lactobacillus acidophilus)
 150 mg
Ox Bile
120 mg
Bromelain (Pineapple)
 100 mg
Pepsin
65 mg
Papain
65 mg
Cellulase
20 mg
Betaine HCl
5 mg
Hemicellulase
5 mg
Lactase
5 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Glutamic Acid · 200 mg OverallScore74
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
This high-potency enzyme formula includes a significant 200mg of glutamic acid to assist digestion. It is a strong choice for those needing more intensive digestive and enzymatic support.
View ingredientView products
Papain · 65 mg OverallScore67
D+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
This multi-enzyme blend provides a solid dose of papain alongside other supporting proteases. It is a well-rounded digestive aid at a reasonable price point.
View ingredientView products
Bromelain (Pineapple) · 100 mg OverallScore60
D Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
This comprehensive digestive enzyme blend includes bromelain to aid in the breakdown of dietary proteins. It is best used with meals to support general digestive comfort and efficiency.
View ingredientView products
96 Value

Super Digestaway

Solaray
4.7
★★★★★
(16102 ratings)
Multi-pathway support is provided through bile powder, pancreatin, and pepsin at a very cost-effective price point. Addition of aloe vera gel and ginger helps soothe the digestive tract while maintaining a broad spectrum of enzymatic activity.
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92 Value

Healthy Inflammation And Joint Support

Garden Of Life Wobenzym N
4.5
★★★★★
(8887 ratings)
Specialized enteric coating protects sensitive enzymes like trypsin and chymotrypsin from stomach acid, ensuring high intestinal activity. Rutin is included alongside pancreatin and papain to support a healthy inflammatory response and efficient protein clearance.
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91 Value

Ultra Digestive Enzymes

Mason Natural
4.5
★★★★★
(128 ratings)
Lactase and acid protease are featured alongside standard enzymes to address a wider variety of dietary sensitivities. Providing 50mg doses of both papain and bromelain makes this a highly efficient and affordable option for comprehensive support.
Other sellers (2)
94 Performance

Joint Health

Garden of Life Wobenzym N
4.8
★★★★★
(651 ratings)
Potent proteolytic enzymes like 180mg of papain and 135mg of bromelain are delivered in an enteric-coated tablet to ensure they reach the intestines. Inclusion of trypsin and rutoside trihydrate provides a sophisticated systemic approach to enzymatic wellness.
Other sellers (1)
91 Performance

Recovery Zymes

Michael's Naturopathic Programs
4.7
★★★★★
(621 ratings)
Pancreatin and 180mg of papain are combined with carminative herbs like anise and fennel to alleviate occasional gas. High doses of proteolytic enzymes facilitate robust protein digestion and tissue recovery support.
Other sellers (2)
91 Performance

Maximum Strength Ultra-Zyme

NaturesPlus
4.7
★★★★★
(1112 ratings)
Concentrated active ingredients like Pancreatin and Glutamic Acid are maintained at high levels for maximum effectiveness. Inclusion of multiple acidophilus strains and ox bile ensures a healthy intestinal environment for those with high digestive support needs.
Other sellers (2)
96 Budget

Super Digestaway

Solaray
4.7
★★★★★
(15653 ratings)
Pancreatin and porcine bile work together to support the efficient breakdown of fats and proteins at a lower cost. Peppermint and ginger rhizome are included to provide extra gastrointestinal ease and comfort after meals.
Other sellers (2)
89 Budget

Chewable Nutri-Zyme Natural Peppermint

Natures Plus
4.5
★★★★★
(142 ratings)
Bromelain and papain are paired with apple cider vinegar to support metabolic processes and digestive efficiency. Peppermint-flavored chewables offer a simpler, more natural alternative for post-meal support.
Other sellers (2)
94 Budget

Chewable Papaya Enzymes

NOW
4.6
★★★★★
(16177 ratings)
Papain, bromelain, and amylase are featured in a high-count format that provides broad enzyme coverage. Whole papaya fruit powder complements the concentrated extracts to help maintain digestive comfort economically.
Other sellers (4)
96 Value

Super Digestaway

Solaray
4.7
★★★★★
(16102 ratings)
Multi-pathway support is provided through bile powder, pancreatin, and pepsin at a very cost-effective price point. Addition of aloe vera gel and ginger helps soothe the digestive tract while maintaining a broad spectrum of enzymatic activity.
Other sellers (3)
92 Value

Healthy Inflammation And Joint Support

Garden Of Life Wobenzym N
4.5
★★★★★
(8887 ratings)
Specialized enteric coating protects sensitive enzymes like trypsin and chymotrypsin from stomach acid, ensuring high intestinal activity. Rutin is included alongside pancreatin and papain to support a healthy inflammatory response and efficient protein clearance.
Other sellers (1)
91 Value

Ultra Digestive Enzymes

Mason Natural
4.5
★★★★★
(128 ratings)
Lactase and acid protease are featured alongside standard enzymes to address a wider variety of dietary sensitivities. Providing 50mg doses of both papain and bromelain makes this a highly efficient and affordable option for comprehensive support.
Other sellers (2)
94 Performance

Joint Health

Garden of Life Wobenzym N
4.8
★★★★★
(651 ratings)
Potent proteolytic enzymes like 180mg of papain and 135mg of bromelain are delivered in an enteric-coated tablet to ensure they reach the intestines. Inclusion of trypsin and rutoside trihydrate provides a sophisticated systemic approach to enzymatic wellness.
Other sellers (1)
91 Performance

Recovery Zymes

Michael's Naturopathic Programs
4.7
★★★★★
(621 ratings)
Pancreatin and 180mg of papain are combined with carminative herbs like anise and fennel to alleviate occasional gas. High doses of proteolytic enzymes facilitate robust protein digestion and tissue recovery support.
Other sellers (2)
91 Performance

Maximum Strength Ultra-Zyme

NaturesPlus
4.7
★★★★★
(1112 ratings)
Concentrated active ingredients like Pancreatin and Glutamic Acid are maintained at high levels for maximum effectiveness. Inclusion of multiple acidophilus strains and ox bile ensures a healthy intestinal environment for those with high digestive support needs.
Other sellers (2)
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