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BioActive Folate & Vitamin B12

Life Extension
4.8
★ ★ ★ ★ ★
(11356 ratings)
Vitamin B12 300 mcg
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Score96

A high-quality pairing of bioactive B12 and folate for heart and metabolic support.

How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
General Health
Energy
Hair Health

Score 96

A high-quality pairing of bioactive B12 and folate for heart and metabolic support.

How scoring works
$9.00($0.10 per serving)
Pure Formulas
$ 9.00
iHerb
$ 9.00
Walmart
$ 9.00
Vitacost
$ 9.00
Amazon
$ 9.00
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Analysis

These capsules combine 300 mcg of methylcobalamin with 680 mcg DFE of L-5-methyltetrahydrofolate. Both ingredients are in their most active forms, allowing the body to use them immediately for DNA support and energy. This is a smart choice for maintaining healthy homocysteine levels and general wellness.

The moderate doses are designed for daily maintenance rather than intensive replenishment. By using bioactive forms, Life Extension ensures that even at lower doses, the nutrients are absorbed and used effectively. It is a practical, clean supplement for long-term health.

Pros

  • Both B12 and Folate are bioactive
  • Supports heart and nerve health synergistically
  • Moderate dose for safe daily use
  • Clean capsule format

Cons

  • B12 dose is lower than standalone products
  • Folate might not be needed by everyone

Warnings

  • High folate can mask a B12 deficiency; ensure you need both

Nutrient quality

97 Highest impact

Utilization of bioactive methylated forms ensures bypass of complex metabolic conversion steps for superior efficiency. Meaningful dosages of both nutrients support critical methylation pathways for foundational wellness.

Ingredient transparency

100 Highest impact

Labeling explicitly identifies the trademarked and bioactive forms of the ingredients for maximum consumer clarity. Serving instructions and active amounts are presented with high precision.

Customer satisfaction

96 Highest impact

Very strong ratings and a massive review count demonstrate broad market approval for the formula's efficacy. Users consistently highlight positive changes in energy and general wellbeing.

Value for money

91 Highest impact

Price per serving is very reasonable for a dual-bioactive formula compared to single-ingredient options. High-quality ingredient forms justify the investment for long-term health maintenance.

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Goals

General Health
Impact
Highest effect
A Goal FitA Strength of SupportB CoverageA+ Formula Quality

Features 300 mcg of methylcobalamin and 680 mcg DFE of methyltetrahydrofolate. These bioactive B-vitamins support cellular energy, DNA repair, and foundational metabolic resilience.

The formula uses bioactive forms to bypass conversion steps and ensure high systemic absorption. By addressing these critical nutrient gaps, it provides well-rounded support for cardiovascular and neurological health.

View goal →
Energy
Impact
Highest effect
A- Goal FitA- Strength of SupportD+ CoverageA+ Formula Quality

Bioactive folate and methylcobalamin are the sole active ingredients in this focused B-vitamin supplement. It is designed to quickly replenish metabolic cofactors necessary for vitality.

Supporting red blood cell health and DNA synthesis directly contributes to systemic energy levels. It appears well aligned for individuals looking for concentrated support in these foundational pathways.

View goal →
Hair Health
Impact
Highest effect
B+ Goal FitB Strength of SupportC CoverageA+ Formula Quality

Combines 300 mcg of methylcobalamin with 680 mcg DFE of methylated folate in a capsule format. These bioactive B-vitamins are crucial for DNA synthesis and the rapid cell division occurring in hair follicles.

Supporting red blood cell health through these nutrients ensures optimal oxygen delivery to the scalp. This targeted pairing is ideal for addressing the nutritional foundations of the hair growth phase.

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Ingredients

IngredientAmount per serving
Folate (L-5-Methyltetrahydrofolate)
 680 mcg DFE
Vitamin B12 (Methylcobalamin)
 300 mcg
Gluten Free Adults 18–50
Report overview
Vitamin B12 (Methylcobalamin) · 300 mcg OverallScore68
A- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyD+ Value
This combination supplement pairs bioactive folate with methylcobalamin for synergistic cardiovascular and neurological support. While the dosage is moderate, it uses premium forms to ensure high absorption and efficacy.
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98 Value

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Methylcobalamin 2.5 mg

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B12 2500 mcg Red Cherry

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Methyl B12 5000 mcg Cherry Flavor

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Liposomal Vitamin B12 Mixed Berry

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