BioActive Folate & Vitamin B12
Life Extension
BioActive Folate & Vitamin B12
4.8
★ ★ ★ ★ ★
(10004 ratings)
Vitamin B12 300 mcg
Score 85.0
A high-quality, bioavailable methylcobalamin B12 product from a reputable brand, ideal for effective daily supplementation and synergistic benefits.
Quantity: 90 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (90 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 85.0
A high-quality, bioavailable methylcobalamin B12 product from a reputable brand, ideal for effective daily supplementation and synergistic benefits.
insights Analysis
Life Extension's BioActive Folate & Vitamin B12 is well-regarded among nutritionists for its commitment to using methylcobalamin, which is the active form of B12 and does not require conversion by the body. This is particularly beneficial for individuals with genetic variations that affect B12 metabolism. The 300mcg dosage, while lower than many supplements, is often sufficient for daily maintenance, especially when combined with folate, which is essential for B12's function. Its higher price per serving reflects the premium quality and bioavailability of the ingredients, making it a good investment for health-conscious consumers.
- Utilizes methylcobalamin, the most bioavailable and active form of Vitamin B12.
- Comes from Life Extension, a highly reputable brand known for quality and research-backed formulations.
- Implied inclusion of BioActive Folate offers synergistic benefits for methylation and overall health.
- Higher price per serving compared to many cyanocobalamin alternatives.
- The 300mcg dosage might be too low for individuals with severe B12 deficiencies seeking rapid repletion.
$9.00($0.10 per serving)
 iHerb | $ 9.00 | |
 Vitacost | $ 9.00 | |
 Amazon | $ 9.00 | |
 Walmart | $ 9.00 | |
 Pure Formulas | $ 9.00 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Folate | 680 mcg DFE |
Vitamin B12 | 300 mcg |
Categories
Vitamin B12 85.0
As a Vitamin B12 supplement, its use of the highly bioavailable methylcobalamin form and association with a quality brand positions it as a top-tier choice for effective B12 supplementation, offering superior absorption and efficacy.
Goals
Brain Health 90.0
The methylcobalamin form is crucial for neurological health and cognitive function, as it directly participates in myelin sheath formation and neurotransmitter synthesis. This active form ensures optimal support for memory, focus, and overall brain well-being, directly contributing to neural integrity.
Cognitive Support 90.0
Methylcobalamin is essential for the healthy functioning of the brain and nervous system, playing a direct role in cognitive processes. This product provides an optimal form for supporting memory, concentration, and overall cognitive performance.
Energy 88.0
Methylcobalamin is efficiently absorbed and directly utilized for cellular energy production. Even at 300mcg, its bioavailable nature means it effectively supports the metabolic pathways required to convert food into energy, potentially offering sustained energy benefits without requiring large doses.
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