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SAMe 200 mg S-Adenosyl-Methionine

Life Extension
4.8
(2046 ratings)
SAMe 200 mg
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Score92

A 200 mg SAMe tablet with professional stability features for gentle metabolic support.

How scoring works
Quantity:30 Tablet(s)(30 servings)
Goals:
Detoxification

Score 92

A 200 mg SAMe tablet with professional stability features for gentle metabolic support.

How scoring works
$18.23($0.60 per serving)
Amazon
$ 18.75
iHerb
$ 18.75
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Analysis

This supplement provides 200 mg of SAMe, which is a good amount for supporting the liver's detoxification pathways or a gentle mood lift. The enteric coating is important here because even at lower doses, SAMe can easily be destroyed by stomach acid.

The individual blister seals ensure that every tablet is fresh when you take it. This fits well for someone who is sensitive to supplements or who only needs a moderate boost in their methylation support.

Pros

  • Excellent protection from moisture
  • Enteric coating for reliable absorption
  • Gentle 200 mg starting dose
  • Trusted brand for transparency

Cons

  • May not be strong enough for some goals
  • 30-day supply goes quickly
  • Lower value than 400 mg packs

Warnings

  • Keep away from heat and direct sunlight
  • Do not take with other mood-altering supplements
  • Consult a professional if you have liver concerns

Nutrient quality

95 Highest impact

A 200 mg dose is well-aligned as a conservative baseline for supporting methylation and detoxification. Enteric coating and blister packaging are high-quality features that ensure the moisture-sensitive compound reaches the absorption site intact.

Ingredient transparency

100 Highest impact

The label clearly specifies the active amount and specific chemical form of the ingredient. Clear serving guidance and full disclosure of inactive components support informed consumer evaluation.

Customer satisfaction

96 Highest impact

Consistently strong user ratings and a large review base indicate high reliability and widespread consumer trust. User feedback confirms that the product performance aligns well with its intended detoxification support role.

Value for money

72 High impact

The price per serving is higher than bulk-sized alternatives but reflects the quality of the enteric delivery system. Total value is moderate for those seeking the specific stabilization features for a 200 mg dose.

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Goals

Impact
Highest effect
A+ Goal FitA- Strength of SupportC CoverageA+ Formula Quality

SAMe serves as a critical universal methyl donor for Phase II conjugation detoxification pathways. This 200 mg dose provides a safe entry point for supporting liver metabolism and systemic clearance.

Stabilized salt forms and enteric coating ensure that the active compound is well-absorbed and protected. Supplemental intake may contribute to healthy methylation and the neutralization of metabolic byproducts.

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Ingredients

IngredientAmount per serving
S-Adenosyl-Methionine
200 mg
Adults 18–50
Report overview
SAMe · 200 mg OverallScore85
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
This 200 mg dose is well-suited for sensitive individuals or those beginning a SAMe regimen. It maintains the same high-stability and bioavailability standards as the higher-dose versions.
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