B12 Methylcobalamin 1000 mcg
Natural Factors
B12 Methylcobalamin 1000 mcg
4.8
★ ★ ★ ★ ★
(9005 ratings)
Vitamin B12 1000 mcg
Score 80.0
A high-quality methylcobalamin B12 supplement at a strong dosage, offering excellent bioavailability and long-term supply for effective daily support.
Quantity: 180 Tablet(s)Servings size: 1 Tablet(s) (180 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 80.0
A high-quality methylcobalamin B12 supplement at a strong dosage, offering excellent bioavailability and long-term supply for effective daily support.
insights Analysis
This Natural Factors supplement features 1000mcg of methylcobalamin, which is widely regarded by nutritionists as the preferred and most active form of B12, requiring no conversion by the body for utilization. This is particularly beneficial for individuals with impaired methylation pathways. The product offers a generous 180 servings, providing a long-lasting supply and good overall value, despite a slightly higher per-serving cost than basic cyanocobalamin options. Its solid review count indicates widespread user satisfaction and trust in the brand's quality, making it a strong contender for those prioritizing bioavailability and efficacy.
- Contains Methylcobalamin, the active and most bioavailable form of B12.
- High dosage (1000mcg) is effective for most needs.
- Large serving count (180 servings) provides good long-term supply.
- From a reputable brand (Natural Factors) with a high number of positive reviews.
- Higher upfront price compared to many alternatives.
- Standard tablet/capsule format (assumed) might not be as rapidly absorbed as sublingual/chewable forms for some individuals.
$17.47($0.09 per serving)
 Amazon | $ 17.47 | |
 iHerb | $ 17.47 | |
 Vitacost | $ 17.47 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B12 | 1000 mcg |
Categories
Vitamin B12 80.0
A high-quality methylcobalamin B12 supplement that offers excellent bioavailability and a strong dosage, providing reliable support for various bodily functions.
Goals
Energy 85.0
The methylcobalamin form ensures direct cellular utilization, leading to more efficient energy metabolism and effective combat against fatigue, supporting sustained vitality throughout the day.
Brain Health 85.0
Being the active form, methylcobalamin is superior for neurological health, directly supporting nerve function, myelin repair, and overall brain well-being without the need for metabolic conversion.
Mood Support 85.0
Methylcobalamin is vital for the methylation cycle, which is central to neurotransmitter production. This makes it highly effective in supporting balanced mood and emotional well-being by optimizing brain chemistry.
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