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Magnesium Bisglycinate Powder

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4.5
★ ★ ★ ★ ★
(10685 ratings)
Magnesium 250 mg
Product Image
Score88
A strong-value bisglycinate powder with a practical amount, limited mainly by conflicting format data and missing scoop guidance.
How scoring works
Quantity:8 Liquid(s) • (91 servings)
Goals:
General Health
Energy
Stress Relief
Cardiovascular Support
Heart Health
Digestive Health
Testosterone Support
Bone Health

Score 88

A strong-value bisglycinate powder with a practical amount, limited mainly by conflicting format data and missing scoop guidance.
How scoring works
$13.90($0.15 per serving)
Vitacost
$ 16.15
Daily Vita
$ 13.90
iHerb
$ 14.69
Pure Formulas
$ 14.27
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Analysis

Bisglycinate is a strong choice for users prioritizing absorption and digestive comfort. The moderate amount leaves room to adjust intake without starting at an excessive serving.

The supplied data identifies the product as liquid despite the powder name. Missing scoop directions also prevent confident measurement from the available information.

The serving cost is low for a bisglycinate powder and the package offers many servings. Actual package directions should be used to resolve the format and measurement uncertainty.

Who is it for
  • Adults seeking gentle magnesium bisglycinate
  • Users who prefer powders
Best for
  • Daily magnesium maintenance
  • Digestive comfort
  • Flexible powder use

Pros

  • Magnesium bisglycinate
  • Moderate amount
  • Low serving cost
  • Large number of servings

Cons

  • Format data conflicts with the name
  • Scoop directions are missing
  • Full excipients are unavailable

Warnings

  • Confirm the serving measurement on the package before use.
  • Magnesium may still cause digestive effects in sensitive users.

Nutrient quality

92 Highest impact

Magnesium bisglycinate provides strong absorption potential at a useful maintenance amount. The focused powder balances broad magnesium support with conservative dosing.

Ingredient transparency

91 Highest impact

The active form and amount are clear without a hidden blend. Complete measuring and intake directions are not supplied in the available information.

Customer satisfaction

70 High impact

The good average rating and very large review count make the aggregate satisfaction signal reasonably dependable. No detailed review text was provided, so recurring complaints and purpose alignment cannot be assessed.

Value for money

95 Highest impact

A premium chelated form and low serving cost provide excellent value. The focused, adjustable powder compares very well with other magnesium products.

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Goals

Impact
Highest effect
A+ Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium bisglycinate supplies a foundational mineral in a highly absorbable form. The clearly stated 250 mg serving is substantial enough to support routine nutritional coverage.

The single-ingredient design is narrow, so it does not address the full range of general wellness needs. Its clean focus and lack of a hidden blend make it a practical magnesium option.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium bisglycinate provides focused support for ATP production, muscle function, and normal nerve signaling. Its energy benefit is most relevant when low magnesium intake or status contributes to fatigue.

The powder clearly supplies a useful elemental amount in a well-absorbed form. A single-mineral design gives strong depth and transparency but does not address alertness or stress resilience.

Study evidence
Magnesium Supportive 4 studies
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Magnesium · 250 mg

A meaningful amount of well-absorbed magnesium supports nerve signaling, muscle relaxation, and stress resilience. The product is focused on a foundational mineral pathway rather than sedative or adaptogenic mechanisms.

Bisglycinate, glycinate, malate, or orotate provides favorable form quality with clear dosing. The simple formula avoids unrelated botanicals and stimulant conflicts.

Study evidence
Magnesium Supportive 13 studies
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium bisglycinate provides focused support for vascular tone, normal rhythm, and cardiac muscle function. The single-mineral formula does not address lipids, endothelial nitric oxide, or antioxidant protection.

The 250 mg amount is useful and clearly disclosed in a highly absorbable chelate. A streamlined powder delivers strong depth in one established cardiovascular pathway.

Study evidence
Magnesium Supportive 123 studies
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium bisglycinate offers a well-absorbed form at a useful 250 mg amount. It directly supports normal cardiac signaling and vascular tone with little formulation clutter.

The formula is intentionally narrow rather than comprehensive. Strong form quality, clear disclosure, and meaningful dose depth make it well suited to focused magnesium support.

Study evidence
Magnesium Supportive 158 studies
Digestive Health
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium bisglycinate supports intestinal muscle function and is usually well tolerated, but it is less directly laxative than citrate. The single-mineral formula does not address other digestive pathways.

The 250 mg amount is useful, fully disclosed, and supplied in a highly absorbable chelated form. Its gentler absorption profile may suit users seeking magnesium without strong stool-softening effects.

Study evidence
Magnesium Supportive 50 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Bisglycinate)
250 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

Magnesium bisglycinate provides a highly absorbable form at a useful 250 mg amount. The label clearly states elemental magnesium, while the single-mineral design keeps the purpose focused. Low serving cost gives the formula strong value even without a patented chelation claim.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  2. Hospital-Acquired Dysmagnesemia and In-Hospital Mortality.
    Cheungpasitporn W; Thongprayoon C; Chewcharat A; Petnak T; Mao MA; Davis PW; Bathini T; Vallabhajosyula S; Qureshi F; Erickson SB · Medical sciences (Basel, Switzerland) · 2024
    Cohort study26,020 participantsGeneral Health forMagnesium
  3. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  4. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  5. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  6. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  7. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  8. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  9. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  10. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  11. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  12. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  13. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  14. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  15. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  16. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  17. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  18. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  19. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  20. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  21. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  22. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  23. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  24. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  25. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  26. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  27. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  28. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  29. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  30. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  31. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  32. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  33. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  34. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  35. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  36. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  37. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  38. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  39. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium