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Magnesium with Vitamin B6

Solgar
4.8
★ ★ ★ ★ ★
(22370 ratings)
Vitamin B6 25 mg
Magnesium 400 mg
Product Image
Score88

A cost-effective, bulk-supply supplement pairing 400 mg of magnesium with B6 for daily energy and muscle support.

How scoring works
Quantity:250 Tablet(s) • (83 servings)
Goals:
Energy
General Health
Stress Relief
Cardiovascular Support
Testosterone Support
Heart Health
Bone Health
Digestive Health

Score 88

A cost-effective, bulk-supply supplement pairing 400 mg of magnesium with B6 for daily energy and muscle support.

How scoring works

Also available as

1 option
100 servings B6 25 mg, Magnesium 400 mg • 100 Tablet(s) • 33 servings $8.24 ($0.24 per serving)
$14.67($0.17 per serving)
iHerb
$ 14.67
Vitacost
$ 15.57
Walmart
$ 18.78
Daily Vita
$ 17.10
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Analysis

Providing a large 250-count supply, this product is designed for consistent daily use. It uses magnesium oxide, which provides a high amount of elemental magnesium even though it isn't as easily absorbed as organic forms.

The B6 in the formula helps move the magnesium into your cells, making the dose more functional. This fits individuals who want a simple, high-count bottle for foundational mineral support.

Pros

  • Excellent value for long-term use
  • High review count suggests reliability
  • Supports energy and heart health
  • Large bottle reduces frequent reordering

Cons

  • Oxide form is not the most bioavailable
  • Contains synthetic pyridoxine hydrochloride
  • Could lead to loose stools in sensitive people

Warnings

  • Check your total B6 intake from other supplements
  • Higher magnesium doses can interact with some medications

Nutrient quality

75 High impact

Magnesium oxide is less absorbable than other mineral forms, which may limit overall efficacy. The dosage for both actives is meaningful and supports foundational health needs.

Ingredient transparency

97 Highest impact

Transparency is excellent, with a clear breakdown of elemental magnesium and vitamin B6 amounts. The labeling provides thorough details on all non-active ingredients.

Customer satisfaction

93 Highest impact

High ratings from an immense number of users demonstrate strong brand trust and reliability. Satisfaction matches the product's intended role in general wellness and relaxation.

Value for money

86 Highest impact

The bulk format provides a superior cost per serving compared to smaller bottle sizes. This makes it a highly economical option for long-term mineral support.

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Goals

Energy
Impact
Highest effect
A+ Goal FitB+ Strength of SupportC+ CoverageA+ Formula Quality

Magnesium is a mandatory cofactor for hundreds of enzymes involved in energy production and ATP utilization. This bulk mineral tablet provides foundational levels of metabolic cofactors to help maintain physical vitality.

Key ingredients include 400 mg of magnesium oxide and 25 mg of Vitamin B6.

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General Health
Impact
Highest effect
A+ Goal FitB Strength of SupportC+ CoverageA+ Formula Quality

Features 400 mg of magnesium oxide combined with vitamin B6 to support cellular energy and muscle function. This large bulk-count format provides consistent foundational mineral support over an extended period.

The addition of B6 helps overcome some of the absorption challenges associated with the oxide form. It is a logical and cost-effective approach to maintaining daily physiological resilience.

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Stress Relief
Impact
Highest effect
A- Goal FitB Strength of SupportB- CoverageA+ Formula Quality

Magnesium oxide is provided alongside Vitamin B6 in this bulk-sized tablet to support mineral status and a calm mind. Each serving delivers 400 mg of magnesium, which is a key mineral for managing the physiological stress response.

The addition of Vitamin B6 helps with the cellular uptake of magnesium, making the 400 mg dose more effective. While cost-efficient, the oxide form is less bioavailable than organic chelates, providing a basic approach to mineral replenishment.

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Cardiovascular Support
Impact
Highest effect
A Goal FitB Strength of SupportC CoverageA+ Formula Quality

Focused mineral support targets heart rhythm and blood vessel relaxation with 400 mg of magnesium and supportive Vitamin B6. This dosage is clinically relevant for individuals looking to maintain healthy circulatory markers and electrical stability.

Formulation relies on magnesium oxide, which may offer limited systemic absorption compared to organic mineral chelates. The addition of B6 provides helpful synergy for cellular uptake, making it a functional choice for foundational maintenance.

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Testosterone Support
Impact
Highest effect
A- Goal FitB- Strength of SupportB- CoverageA+ Formula Quality

Magnesium oxide and Vitamin B6 are combined to support systemic mineral levels and healthy hormone regulation. Vitamin B6 acts as a critical cofactor for steroid hormone synthesis and can help manage prolactin levels, which may otherwise inhibit natural hormone production.

The reliance on the oxide form for magnesium significantly limits its systemic bioavailability compared to organic chelates. While the addition of Vitamin B6 provides a logical synergy, the overall functional quality of the mineral component is low for targeted hormonal support.

View goal →
Heart Health
Impact
High effect
A- Goal FitB Strength of SupportC CoverageA Formula Quality

This bulk-size combination of magnesium and Vitamin B6 provides foundational support for cardiac rhythm and vascular relaxation. It offers a practical and affordable option for maintaining essential mineral balance over the long term.

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Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 25 mg
Magnesium (Magnesium Oxide)
 400 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 25 mg OverallScore74
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
This magnesium and B6 combination uses a standard synthetic form of the vitamin at a safe dosage. It is a highly affordable option for those seeking a basic, large-supply supplement.
View ingredientView products
Magnesium (Magnesium Oxide) · 400 mg OverallScore59
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC+ Value
Providing a high dose of magnesium alongside Vitamin B6, this bulk-sized supplement is very cost-effective. While the magnesium oxide form is not the most absorbable, the B6 helps maximize what is taken up.
View ingredientView products
95 Value

Magnesium 500 mg

Nature's Life
4.8
★★★★★
(14499 ratings)
Combining citrate, malate, and oxide with vitamin B6 ensures balanced absorption and high metabolic utility. This multi-source blend offers a more advanced profile than the original while remaining highly affordable.
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Mag Glycinate 350 mg

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4.6
★★★★★
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Magnesium Citrate Pure Powder

NOW
4.5
★★★★★
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Magnesium Malate 500 mg

Seeking Health
4.7
★★★★★
(1799 ratings)
DiMagnesium malate is an organic chelate that supports cellular energy production more effectively than inorganic mineral salts. The high 500 mg dose and superior absorption profile make this a premier choice for physical vitality.
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P-5-P 50 mg

Nutricost
4.8
★★★★★
(930 ratings)
Active pyridoxal 5-phosphate ensures that vitamin B6 is immediately available for biological reactions without hepatic processing. This coenzyme form is much more efficient for metabolic and neurological health than standard B6.
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CellularActive P5P 50 mg

Bluebonnet
4.8
★★★★★
(457 ratings)
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Magnesium Caps 500 mg

Life Extension
4.8
★★★★★
(78048 ratings)
Utilizing a blend of citrate, succinate, and glycinate ensures much better systemic uptake than relying solely on magnesium oxide. This bulk supply is highly economical while providing a higher elemental dose of 500 mg.
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98 Budget

Magnesium Powder Unflavored

California Gold Nutrition
4.7
★★★★★
(3329 ratings)
Magnesium citrate in a powder format allows for flexible dosing and often results in better absorption compared to large tablets. This unflavored option provides a massive number of servings at an exceptionally low price.
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Magnesium Chloride

Alta Health Products
4.4
★★★★★
(2385 ratings)
Magnesium chloride is recognized for having better bioavailability than magnesium oxide for cellular repletion. This simple, single-ingredient approach is a cost-effective way to support heart and muscle function.
Other sellers (4)
95 Value

Magnesium 500 mg

Nature's Life
4.8
★★★★★
(14499 ratings)
Combining citrate, malate, and oxide with vitamin B6 ensures balanced absorption and high metabolic utility. This multi-source blend offers a more advanced profile than the original while remaining highly affordable.
Other sellers (3)
95 Value

Mag Glycinate 350 mg

ZHOU
4.6
★★★★★
(1171 ratings)
Magnesium glycinate is much gentler on the digestive tract and more bioavailable than magnesium oxide. The inclusion of black pepper extract further assists in the systemic uptake of this essential mineral.
Other sellers (3)
97 Value

Magnesium Citrate Pure Powder

NOW
4.5
★★★★★
(11460 ratings)
Pure magnesium citrate powder offers high solubility and is a reliable way to reach therapeutic targets for mineral repletion. This format provides complete transparency and avoids the fillers often found in tablet formulas.
Other sellers (5)
98 Performance

Magnesium Malate 500 mg

Seeking Health
4.7
★★★★★
(1799 ratings)
DiMagnesium malate is an organic chelate that supports cellular energy production more effectively than inorganic mineral salts. The high 500 mg dose and superior absorption profile make this a premier choice for physical vitality.
Other sellers (1)
98 Performance

P-5-P 50 mg

Nutricost
4.8
★★★★★
(930 ratings)
Active pyridoxal 5-phosphate ensures that vitamin B6 is immediately available for biological reactions without hepatic processing. This coenzyme form is much more efficient for metabolic and neurological health than standard B6.
Other sellers (0)
95 Performance

CellularActive P5P 50 mg

Bluebonnet
4.8
★★★★★
(457 ratings)
High-quality pyridoxal 5-phosphate provides optimized support for neurotransmitter synthesis and energy pathways. This focused B6 replenishment is better for those who require active forms for maximum metabolic utility.
Other sellers (3)
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