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SAMe 200 mg

NOW
4.6
(3080 ratings)
SAMe 200 mg
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Score95

A 200 mg SAMe capsule with acid-resistant technology for gentle mood and liver support.

How scoring works
Quantity:60 Capsule(s)(60 servings)
Goals:
Detoxification

Score 95

A 200 mg SAMe capsule with acid-resistant technology for gentle mood and liver support.

How scoring works
$18.00($0.30 per serving)
Pure Formulas
$ 24.18
iHerb
$ 24.48
iHerb
$ 24.48
Vitacost
$ 23.33
Daily Vita
$ 23.10
Daily Vita
$ 18.00
Amazon
$ 23.10
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Analysis

This product provides 200 mg of SAMe, which may support the liver's natural detoxification pathways and basic emotional wellness. It uses a stabilized salt form in a capsule that resists stomach acid, which helps protect the delicate active ingredient.

This lower dose allows for more flexibility in finding the right amount for your body. It is a good choice for sensitive individuals or those who want to split their intake throughout the day.

Pros

  • Acid-resistant capsule for protection
  • Flexible 200 mg starting dose
  • Uses a stabilized salt form
  • Helpful for liver detoxification goals

Cons

  • Bottle packaging is less protective than blisters
  • May require taking multiple capsules for higher needs
  • SAMe is sensitive to air once the bottle is open

Warnings

  • Keep the bottle tightly closed in a cool place
  • Do not take with other serotonin-modulating supplements
  • Consult a professional if you have bipolar disorder

Nutrient quality

89 Highest impact

A 200 mg dose provides a conservative entry point for supporting methylation and detoxification. While the salt form is stabilized, capsule delivery may offer less moisture protection than enteric tablets for this sensitive compound.

Ingredient transparency

100 Highest impact

The specific salt form of SAMe is clearly identified, which is critical for evaluating product stability. All labeling for dosages and serving sizes is clear, aiding in safe and accurate supplementation.

Customer satisfaction

94 Highest impact

Consistently positive user ratings across a large review base suggest high reliability for detoxification support. Feedback indicates that the product performance is well-aligned with the expectations for a 200 mg dose.

Value for money

97 Highest impact

A competitive price point for a stabilized SAMe product provides good value for regular users. Cost per serving is very reasonable for this specific nutrient, making it accessible for long-term use.

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Goals

Impact
Highest effect
A+ Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality

S-adenosyl-l-methionine acts as a universal methyl donor, supporting Phase II methylation within the liver. This pathway is critical for the detoxification of hormones and environmental chemicals.

Acid-resistant capsules help protect the active compound from stomach acid, improving intestinal delivery. This supplement appears well aligned with supporting foundational metabolic clearance pathways.

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Ingredients

IngredientAmount per serving
SAMe (S-Adenosyl-L-Methionine Disulfate Tosylate)
200 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
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B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value
This 200 mg formulation is an excellent starting dose for those new to SAMe supplementation. It utilizes acid-resistant capsules to protect the stabilized salt form, though the bottle packaging requires careful storage.
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