B-12 1000 mcg
21st Century
B-12 1000 mcg
4.7
★ ★ ★ ★ ★
(9825 ratings)
Vitamin B12 1000 mcg
Score 72.0
A highly economical 1000 mcg B12 tablet (cyanocobalamin) offering excellent value for basic, daily supplementation.
Quantity: 110 Tablet(s)Servings size: 1 Tablet(s) (110 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 72.0
A highly economical 1000 mcg B12 tablet (cyanocobalamin) offering excellent value for basic, daily supplementation.
insights Analysis
21st Century's B-12 1000 mcg is a budget-friendly option that delivers a respectable dosage of cyanocobalamin. Its main appeal lies in its incredibly low price per serving, making consistent B12 supplementation accessible for almost any budget. As a standard tablet, it relies on digestion for absorption, which may not be ideal for individuals with malabsorption issues. However, for most people seeking a cost-effective way to maintain their B12 levels, this product provides a simple and effective solution. The added calcium is a minor, but generally harmless, inclusion.
- Extremely low price per serving, offering great value.
- Provides a standard and effective 1000 mcg dosage of B12.
- High review count indicates widespread consumer satisfaction.
- Contains a small amount of calcium, which can be a minor bonus for some.
- Uses cyanocobalamin, a synthetic form requiring conversion in the body.
- Standard tablet form may lead to less efficient absorption compared to sublingual or liquid B12.
- Not ideal for individuals with significant absorption problems.
- Absorption efficacy may vary among individuals; consult a doctor if you suspect malabsorption.
$7.18($0.06 per serving)
 iHerb | $ 7.18 | |
 Amazon | $ 14.98 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin B12 (Cyanocobalamin) | 1000 mcg |
| Calcium (Calcium Carbonate) | 100 mg |
Categories
Vitamin B12 72.0
As a Vitamin B12 supplement, it excels in affordability and provides a solid dose, making it a practical choice for routine B12 maintenance in tablet form.
Goals
Energy 72.0
Provides a sufficient dose of B12 to support cellular energy production, helping to alleviate general fatigue, especially for those with adequate absorption.
Brain Health 72.0
This B12 supplement contributes to nerve health and essential neurological processes, supporting overall brain function for general well-being.
Mood Support 72.0
Adequate B12 levels are important for neurotransmitter synthesis, and this product provides a foundational amount that can aid in mood balance.
Recommended Alternatives
95 Value 
Fully Active B12 1500 mcg
Doctor's Best
4.7
★★★★★
(30986 ratings)
Delivers the superior Methylcobalamin form at a very competitive price per serving, offering excellent value for an active B12.
93 Value 
Methyl B-12 1000 mcg Lemon Flavor
Jarrow Formulas
4.7
★★★★★
(11077 ratings)
Provides Methylcobalamin, the active form, at a better price point than many similar quality products, representing solid value.