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Vitamin D Supreme with Vitamin K1 and K2

Designs for Health
4.7
★ ★ ★ ★ ★
(4043 ratings)
Vitamin D 5000 IU
Vitamin K 550 mcg
Product Image
Score86

A potent D3 and Vitamin K complex for intensive immune and skeletal support.

How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
General Health
Immunity
Anti-Inflammatory Support
Anti-Aging
Testosterone Support
Cardiovascular Support
Energy
Heart Health
Bone Health

Score 86

A potent D3 and Vitamin K complex for intensive immune and skeletal support.

How scoring works

Also available as

1 option
180 servings D 5000 IU, K 550 mcg • 180 Capsule(s) • 180 servings $109.44 ($0.60 per serving)
$38.49($0.64 per serving)
Pure Formulas
$ 38.49
iHerb
$ 38.49
Amazon
$ 38.49
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Analysis

Providing 5,000 IU of D3 and 550 mcg of Vitamin K, this product targets the regulation of calcium metabolism and immune health. These fat-soluble vitamins work together to support arterial health and skeletal integrity.

The formula is clean and avoids unnecessary fillers, making it suitable for those with sensitivities. As with all high-dose D3 products, it is best consumed with a meal containing fats to ensure the nutrients are used effectively.

Pros

  • Therapeutic 5,000 IU dose of D3
  • Supports calcium transport
  • High-quality clean formula
  • Meaningful Vitamin K levels

Cons

  • Dry capsule may limit absorption without fat
  • Price per serving is on the higher side
  • No specific MK-7 mentioned

Warnings

  • Must be taken with a fat-containing meal
  • Consult a professional if taking anticoagulants
  • Monitor serum Vitamin D levels regularly

Nutrient quality

91 Highest impact

Cholecalciferol and vitamin K support bone density and cardiovascular health through meaningful dosages. Bioavailable nutrient forms appear well aligned for correcting systemic deficiencies.

Ingredient transparency

91 Highest impact

Labeling clearly discloses the amounts of key fat-soluble vitamins. Missing information regarding the specific vitamin K subtype slightly reduces the precision of the ingredient profile.

Customer satisfaction

95 Highest impact

High market acceptance is demonstrated by a massive review volume and strong average rating. Consistent feedback suggests that the formula reliably delivers the intended health benefits.

Value for money

63 Moderate impact

Price per serving is relatively high for a simple two-ingredient vitamin supplement. Smaller bottle size increases the cost per unit compared to the larger count version.

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Goals

General Health
Impact
Highest effect
A+ Goal FitA Strength of SupportB CoverageA+ Formula Quality

Vitamin D3 and Vitamin K are combined to support foundational calcium metabolism and immune health. These nutrients appear well aligned with long-term cardiovascular and skeletal wellness.

A high-potency 5,000 IU dose of Vitamin D3 provides robust support for achieving optimal blood levels.

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Immunity
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality

Vitamin D3 and Vitamin K are combined to support immune regulation and overall systemic balance. Vitamin D3 is a potent modulator of both the innate and adaptive immune systems, influencing the activity of various white blood cells.

The 5000 IU dose is effective for maintaining and raising blood levels to support optimal immune vigilance. This simplified formula focuses on a high-potency delivery of fat-soluble vitamins.

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Anti-Inflammatory Support
Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA+ Formula Quality

This practitioner-grade supplement provides a high dose of 5000 IU of Vitamin D3 combined with Vitamin K. Vitamin D3 is a master regulator of the immune system and has significant effects on reducing pro-inflammatory cytokines.

The inclusion of Vitamin K provides essential synergy, particularly for directing calcium metabolism and supporting cardiovascular health. It offers intensive and potently dosed support for individuals requiring significant systemic intervention.

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Anti-Aging
Impact
Highest effect
A- Goal FitB+ Strength of SupportB- CoverageA+ Formula Quality

Vitamin D3 and Vitamin K provide a powerful combination for skeletal integrity and cardiovascular flexibility. This synergy addresses the risk of soft tissue calcification, which is a significant factor in physiological aging.

A high-potency dose of 5,000 IU of D3 is well aligned with deficiency correction in older populations. While the ingredient pairing is sound, delivering these fat-soluble nutrients in a dry capsule without a lipid base may hinder their overall absorption efficiency.

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Testosterone Support
Impact
Highest effect
A Goal FitB+ Strength of SupportD+ CoverageA+ Formula Quality

Vitamin D3 at a therapeutic dose of 5000 IU provides powerful support for the building blocks of hormone synthesis. Correcting Vitamin D status is a primary clinical strategy for maintaining healthy endocrine function and testosterone production.

Cholecalciferol acts as a direct pro-hormone with receptors specifically located in the testes. While essential, the dry capsule format lacks the lipids necessary for optimal fat-soluble vitamin absorption.

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Cardiovascular Support
Impact
Highest effect
A- Goal FitB- Strength of SupportC CoverageA+ Formula Quality

This high-potency formula combines Vitamin D3 and Vitamin K to support healthy calcium metabolism. Such synergy is essential for maintaining arterial flexibility and overall cardiovascular health.

Cholecalciferol and Menaquinone are the primary ingredients, delivered at robust dosages. This specific combination is well-regarded for its role in ensuring calcium is directed to bones rather than blood vessel walls.

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Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
 5000 IU
Vitamin K
550 mcg
Gluten Free Adults 18–50
Report overview
Vitamin D (Cholecalciferol) · 5000 IU OverallScore69
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD+ Value
This practitioner-grade supplement provides a high dose of Vitamin D3 combined with Vitamin K. It is a clean formula designed for therapeutic use, though the capsule form lacks a lipid base for absorption.
View ingredientView products
Vitamin K · 550 mcg OverallScore33
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD+ Value
This supplement combines high-dose Vitamin D3 with a large dose of Vitamin K. However, the exact subtype of Vitamin K2 is not clearly identified on the panel, reducing its clinical predictability.
View ingredientView products
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