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Calcium Magnesium Zinc With L-Glutamic Acid 1000 mg : 500 mg : 50 mg

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4.8
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(5973 ratings)
Glutamic Acid 100 mg
Calcium 1000 mg
Zinc 50 mg
Magnesium 500 mg
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Score75
High mineral coverage and good value are offset by basic forms and an excessive zinc amount for long-term routine use.
How scoring works
Quantity:250 Tablet(s) • (83 servings)
Goals:
General Health
Bone Health
Immunity

Score 75

High mineral coverage and good value are offset by basic forms and an excessive zinc amount for long-term routine use.
How scoring works
$27.19($0.32 per serving)
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$ 27.19
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$ 27.19
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Analysis

The formula provides a large calcium amount with magnesium and zinc for bone and mineral support. Calcium citrate and zinc gluconate improve part of the form profile, while glutamic acid is a minor addition.

Calcium carbonate and magnesium oxide are less soluble choices than the stronger forms in the blend. Zinc reaches 50 mg, which makes the product less suitable for prolonged daily use and creates concern about copper balance.

Three tablets per serving and a large bottle provide strong value for deliberate high-dose mineral use. People seeking routine maintenance may prefer lower mineral amounts and included copper.

Who is it for
  • Adults seeking high-dose calcium and magnesium
  • Users prioritizing mineral value
  • People using zinc for a defined short-term need
Best for
  • High-potency mineral intake
  • Bone nutrition
  • Long-supply value

Pros

  • Provides substantial calcium and magnesium
  • Includes calcium citrate
  • Offers a large number of servings
  • Uses a focused mineral formula

Cons

  • Contains magnesium oxide
  • Relies partly on calcium carbonate
  • Zinc amount is very high
  • Does not include balancing copper

Warnings

  • Long-term 50 mg zinc intake may contribute to copper deficiency
  • The 500 mg magnesium amount may cause diarrhea or cramping
  • High supplemental calcium should be counted with diet and separated from medicines whose absorption it can reduce

Nutrient quality

68 High impact

Several weaker or vague forms limit ingredient quality. Aggressive dosing is the main concern.

.

Ingredient transparency

81 Highest impact

Most active amounts are clearly disclosed. Missing directions and inactive ingredients keep disclosure incomplete.

.

Customer satisfaction

71 High impact

The supplied average is strong and rests on a large review count. No review text was provided to assess recurring complaints or firsthand experiences.

.

Value for money

81 Highest impact

Serving efficiency is favorable for the disclosed formula. A focused active profile supports value.

.
Report analysis

Goals

General Health
General Health
Impact
High effect
A- Goal FitD+ Strength of SupportC+ CoverageB- Formula Quality
Magnesium · 500 mgZinc · 50 mg

Calcium, magnesium, and zinc provide broad mineral support for skeletal, muscular, and immune functions. Magnesium oxide has weak systemic absorption, while the zinc amount is too high for routine long-term use without attention to copper balance.

The formula covers several foundational needs, but its amounts and forms are uneven. The 50 mg zinc serving without copper may contribute to copper depletion if used regularly over time.

Study evidence
Magnesium Supportive 114 studies
Zinc Supportive 60 studies
Bone Health
Bone Health
Impact
High effect
A- Goal FitC- Strength of SupportC- CoverageC Formula Quality
Magnesium · 500 mgCalcium · 1000 mgZinc · 50 mg

Calcium and magnesium provide major structural minerals, with zinc adding a supporting cofactor. The formula lacks vitamin D and vitamin K to guide calcium absorption and placement.

Calcium is concentrated in a large serving, while magnesium oxide has limited systemic absorption. The zinc amount exceeds the adult daily upper limit and long-term use may impair copper status because no copper is included.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Zinc Supportive 33 studies
Immunity
Immunity
Impact
High effect
A- Goal FitD Strength of SupportC CoverageC+ Formula Quality
Magnesium · 500 mgZinc · 50 mg

Zinc is directly relevant to immunity, and the formula also provides large calcium and magnesium amounts. Exact mineral quantities are disclosed across the three-tablet serving.

The 50 mg zinc amount exceeds the adult upper limit and lacks copper, creating a concern for prolonged daily use. Magnesium oxide and calcium carbonate also weaken absorption quality and may contribute to digestive discomfort.

Study evidence
Magnesium Supportive 8 studies
Zinc Supportive 73 studies
Energy
Energy
Impact
Moderate effect
B+ Goal FitD+ Strength of SupportD+ CoverageC+ Formula Quality
Magnesium · 500 mg

Magnesium supports ATP-dependent enzymes, while calcium and zinc contribute to muscle and cellular functions. The mineral amounts are substantial and clearly listed.

Magnesium oxide is poorly absorbed, and 50 mg zinc exceeds the usual adult upper intake level without balancing copper. The formula is more suitable for targeted mineral use than routine energy support.

Study evidence
Magnesium Supportive 4 studies
Hair Health
Hair Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportC- CoverageC- Formula Quality
Zinc · 50 mg

Zinc may reduce hair loss caused by zinc deficiency, while magnesium and calcium add general mineral support. The formula is not targeted to structural proteins or hormonal hair loss.

Zinc and magnesium use mixed forms that include less absorbable oxides, and the three-tablet mineral load may affect tolerance. The 50 mg zinc amount exceeds the adult daily upper limit and can cause nausea or copper deficiency with ongoing use.

Study evidence
Zinc Supportive 22 studies
Vision Support
Vision Support
Impact
Moderate effect
B Goal FitC+ Strength of SupportD+ CoverageF Formula Quality
Zinc · 50 mg

Zinc has a recognized role in retinal function and established vision formulas, but the wider calcium and magnesium product is not designed for ocular support. The zinc amount is excessive for routine long-term use and no copper is included.

Mineral forms and amounts are disclosed, although magnesium oxide weakens quality and the formula lacks carotenoids or ocular lipids. Long-term use of the high zinc amount may cause nausea and copper deficiency, which can lead to anemia or nerve problems.

Study evidence
Zinc Supportive 39 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Carbonate, Calcium Citrate)
 1000 mg
Magnesium (Magnesium Oxide)
 500 mg
Zinc (Zinc Gluconate)
 50 mg
L-Glutamic Acid
100 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Glutamic Acid · 100 mg OverallScore92
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The clearly identified L-form and 100 mg dose provide a useful amount of biologically active glutamic acid. A hydrochloride form would be more specifically suited to supporting mineral-complex absorption, so the standard form is a compromise. The low cost per serving adds strong practical value.

View ingredientView products
Calcium (Calcium Carbonate, Calcium Citrate) · 1000 mg OverallScore80
A- Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA+ Value

Calcium citrate improves the form profile, although carbonate supplies part of the blend. The 1000 mg calcium amount is likely too large for optimal absorption in one serving. The low serving cost is attractive, but the large single dose is less efficiently absorbed.

View ingredientView products
Zinc (Zinc Gluconate) · 50 mg OverallScore64
B Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyC Value

Zinc gluconate is a well-absorbed form, but the hard tablet is a less favorable delivery method. The amount exceeds the daily upper limit and no copper is included, which raises concern for long-term use. Cost per effective serving is moderate.

View ingredientView products
Loading alternative details
80 Performance

Magnesium & Calcium

NOW
<p>Calcium citrate, magnesium citrate, glycinate, and taurate plus vitamin D3 and monomethionine zinc provide broader form quality than a mostly carbonate-and-oxide blend. The listed magnesium amount is unusually high and still includes oxide, creating a substantial tolerance concern.</p>
80 Performance

Calcium Magnesium plus Zinc

Solgar
<p>Citrate and gluconate forms improve calcium, magnesium, and zinc coverage while keeping the formula focused. Calcium carbonate and magnesium oxide remain, but the zinc amount is less aggressive than several original formulas.</p>
76 Performance

Calcium Magnesium Plus Zinc

Bluebonnet
<p>Calcium, magnesium, zinc, copper, and several useful forms create broader trace-mineral coverage than a basic three-mineral formula. Magnesium remains high enough to cause loose stools, while horsetail and tiny boron additions contribute little.</p>
78 Budget

Calcium Magnesium Zinc + Vitamin D3

Best Naturals
<p>Lower serving cost keeps substantial calcium, magnesium, zinc, and vitamin D3 with some citrate and gluconate forms. Carbonate and oxides remain, and the zinc amount is assertive for routine use.</p>
79 Budget

Calcium Magnesium & Zinc

Sundown
<p>Economical calcium, magnesium, and zinc coverage preserves the core mineral purpose. Carbonate and oxide forms limit absorption quality, though zinc citrate and mineral gluconates add some form variety.</p>
78 Budget

Chelated Calcium Magnesium Zinc

American Health
<p>Very low serving cost retains the same three core minerals at substantial amounts. Carbonate and oxide forms dominate, so value rather than form quality is the main advantage.</p>
77 Value

Calcium Magnesium Zinc + Vitamin D3

AN Amazing Nutrition Amazing Formulas
<p>A very low serving cost adds vitamin D3 to substantial calcium, magnesium, and zinc coverage. Repeated form entries obscure source contributions, and the zinc amount is aggressive for long-term routine use.</p>
80 Value

Natural Calcium Magnesium & Zinc with Vitamin D3

Spring Valley
<p>Very low routine cost preserves calcium, magnesium, zinc, and vitamin D3 with a simpler label. Mineral forms are not identified, so absorption quality cannot be compared confidently.</p>
85 Value

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a lower, more balanced mineral load with strong serving value. Zinc and glutamic acid are absent, but the simpler formula may be easier to tolerate than high-dose combinations.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
    Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Cross-sectional study14,705 participantsBone Health forCalcium
  2. Bone turnover and the response to alendronate treatment in postmenopausal osteoporosis.
    Gonnelli S; Cepollaro C; Pondrelli C; Martini S; Montagnani A; Monaco R; Gennari C · Calcified tissue international · 1999
    Randomized trial100 participantsBone Health forCalcium
  3. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  4. Association between magnesium deficiency scores and hip bone health in adults: a population-based study.
    Li S; Chang W; Wu G; Wang K; Sun X; Sun H; Zhou J · Magnesium research · 2025
    Cross-sectional study13,259 participantsBone Health forMagnesium
  5. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  6. Excess serum zinc concentration is associated with incident fracture in men: Tehran lipid and glucose study.
    Bahadoran Z; Hadaegh F; Azizi F; Ghasemi A · Scientific reports · 2026
    Cohort study1,968 participantsBone Health forZinc
  7. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  8. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  9. Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial.
    Bhatnagar S; Bahl R; Sharma PK; Kumar GT; Saxena SK; Bhan MK · Journal of pediatric gastroenterology and nutrition · 2004
    Randomized trial287 participantsDigestive Health forZinc
  10. Identifying risk factors for vomiting during diarrhea: A secondary analysis of a randomized trial of zinc supplementation.
    Edwards JG; Dhingra P; Liu E; Dhingra U; Dutta A; Sudfeld CR; Deb S; Somji S; Aboud S; Kisenge R; Sazawal S; Ashorn P; Simon J; Manji KP; Duggan CP · Journal of pediatric gastroenterology and nutrition · 2025
    Randomized trial4,500 participantsDigestive Health forZinc
  11. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  12. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  13. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  14. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  15. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  18. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  19. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  20. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  21. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  22. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  23. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  24. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  25. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  26. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  27. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  28. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  29. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  30. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  31. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  32. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  33. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  34. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  35. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  36. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  37. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  38. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  39. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  40. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  41. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  42. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  43. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledHeart Health forMagnesium
  44. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  45. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  46. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  47. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forMagnesium
  48. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  49. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A · Frontiers in nutrition · 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  50. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ · Science (New York, N.Y.) · 2013
    Single-arm trialImmunity forMagnesium
  51. Effect of magnesium on granulocyte function and on the exercise induced inflammatory response.
    Mooren FC; Golf SW; Völker K · Magnesium research · 2003
    Randomized trialImmunity forMagnesium
  52. Maternal and neonatal outcomes following magnesium sulfate in the setting of chorioamnionitis: a meta-analysis.
    Pergialiotis V; Sapantzoglou I; Rodolaki K; Varthaliti A; Theodora M; Antsaklis P; Thomakos N; Stavros S; Daskalakis G; Papapanagiotou A · Archives of gynecology and obstetrics · 2024
    Meta-analysis6,559 participants8 studies pooledImmunity forMagnesium
  53. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  54. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  55. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  56. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  57. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  58. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  59. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  60. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  61. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  62. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  63. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  64. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  65. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  66. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  67. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  68. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  69. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  70. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  71. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  72. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc