Vitamin B6 100 mg
Solgar
Vitamin B6 100 mg
4.8
★ ★ ★ ★ ★
(377 ratings)
Vitamin B6 100 mg
Score 72.0
Solgar's 100mg Pyridoxine HCl B6 offers a standard dose from a reputable brand, but the form and higher dose warrant consideration for long-term use.
Quantity: 100 Capsule(s)Servings size: 1 Vegetable Capsule(s) (100 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
leaderboard Score 72.0
Solgar's 100mg Pyridoxine HCl B6 offers a standard dose from a reputable brand, but the form and higher dose warrant consideration for long-term use.
insights Analysis
This Vitamin B6 supplement by Solgar offers 100mg of Pyridoxine Hydrochloride, a widely available form of the vitamin that participates in numerous bodily functions including energy metabolism, neurotransmitter synthesis, and red blood cell formation. While effective for those requiring significant B6 supplementation, the 100mg dose of Pyridoxine HCl can be a concern for long-term daily use as it approaches the upper limits associated with potential peripheral neuropathy according to some health authorities and online discussions. For optimal absorption and safety, especially for individuals with genetic variations affecting B vitamin metabolism, the coenzyme form (Pyridoxal 5-Phosphate or P-5-P) is often recommended by nutritionists as a superior alternative.
- Reputable brand (Solgar) known for quality.
- Provides a substantial 100mg dose of Vitamin B6 for deficiency support.
- Convenient capsule form.
- Uses Pyridoxine Hydrochloride, which is less bioavailable than P-5-P and carries a higher risk of neuropathy at 100mg compared to P-5-P.
- 100mg daily dosage of Pyridoxine HCl is considered high for long-term general supplementation by some experts.
- Not the most cost-effective option compared to other 100mg Pyridoxine HCl supplements.
- Long-term daily intake of 100mg Pyridoxine Hydrochloride may contribute to peripheral neuropathy in some sensitive individuals. Consult a healthcare professional for appropriate dosage, especially if taking other B6-containing supplements.
$8.69($0.08 per serving)
 Vitacost | $ 8.69 | |
 Pure Formulas | $ 9.37 | |
 Daily Vita | $ 9.37 | |
 iHerb | $ 9.37 |
bolt Effectiveness for goals
Yes, Vitamin B6 is a widely recognized and often recommended treatment for nausea and vomiting in pregnancy, commonly known as morning sickness. It is considered a first-line pharmacological therapy for mild to moderate symptoms. Pregnant individuals should consult their healthcare provider before taking any supplements.
Vitamin B6, or pyridoxine, is crucial for over 100 enzyme reactions, primarily involved in protein metabolism, red blood cell formation, and nervous system health. It plays a key role in metabolic processes that convert food into energy. Maintaining adequate B6 levels supports overall health and proper bodily functions.
Absolutely, Vitamin B6 is vital for brain development and function, and for maintaining a healthy nervous system. It is involved in the synthesis of several key neurotransmitters, such as serotonin, dopamine, and GABA, which regulate mood, sleep, and cognitive processes. Adequate B6 intake is essential for proper nerve signaling.
Some studies suggest that Vitamin B6 supplementation may help reduce certain PMS symptoms, particularly mood swings, irritability, and breast tenderness. The exact mechanism is not fully understood, but it may involve its role in neurotransmitter synthesis. However, evidence is mixed, and more robust research is needed.
Vitamin B6 is involved in the production of neurotransmitters like serotonin and norepinephrine, which are critical for mood regulation. Some research indicates that B6 supplementation may positively influence mood and reduce symptoms of depression, particularly in individuals with a deficiency. However, it should not replace prescribed treatments for mental health conditions.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men and women (19-50 years) is 1.3 mg per day. For those over 50, it is 1.7 mg for men and 1.5 mg for women. These recommendations are for healthy individuals.
Yes, taking excessively high doses of Vitamin B6, particularly from supplements, can be harmful. The most well-known adverse effect is sensory neuropathy, which can cause numbness and tingling in the extremities. This risk increases with doses significantly above the Tolerable Upper Intake Level (UL) of 100 mg/day.
The Tolerable Upper Intake Level (UL) for Vitamin B6 in adults is 100 mg per day. Consuming amounts significantly above this UL, particularly from supplements, can lead to adverse effects like peripheral neuropathy. It is advisable not to exceed this limit without professional guidance.
There is no specific "best" time to take Vitamin B6; it can be taken at any time of day. Consistency in taking the supplement is generally more important than the exact timing. Some individuals may prefer to take it with a meal to avoid potential stomach upset.
Vitamin B6 supplements commonly contain pyridoxine hydrochloride (pyridoxine HCl). The active coenzyme form, pyridoxal 5'-phosphate (P5P), is also available in some supplements. Other forms like pyridoxal and pyridoxamine also exist in food.
health_and_safety Safety & interactions
Long-term intake of high doses, typically exceeding 200 mg per day, can lead to sensory peripheral neuropathy, characterized by numbness, tingling, and pain in the extremities. Other less common side effects might include skin lesions, photosensitivity, and gastrointestinal issues. These effects usually resolve after discontinuing supplementation.
For adults, the tolerable upper intake level (UL) for Vitamin B6 is set at 100 mg per day from supplements and fortified foods. Consuming amounts above this UL regularly increases the risk of adverse effects, primarily neurological damage. This limit is established to prevent potential harm.
The primary and most concerning symptom of Vitamin B6 toxicity, typically from chronic high doses, is sensory peripheral neuropathy. This involves symptoms like numbness, tingling, and burning pain, often starting in the hands and feet. Other less common signs might include skin lesions or gastrointestinal upset.
Yes, Vitamin B6 can interact with several medications. For instance, it may reduce the effectiveness of levodopa (used for Parkinson's disease) and can interact with anti-seizure medications like phenytoin and phenobarbital. It is important to consult a healthcare provider when combining Vitamin B6 supplements with prescription drugs.
Vitamin B6 is generally considered safe during pregnancy and breastfeeding when taken within recommended dietary allowances. Higher doses might be used under medical supervision for specific conditions like severe morning sickness. Always discuss any supplementation with a healthcare provider to ensure appropriate dosing.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 100 mg |
Categories
Vitamin B6 72.0
This product provides a high dose of Vitamin B6 in the Pyridoxine Hydrochloride form, which is widely available and used to address deficiencies. While it effectively delivers the nutrient, the preference for the more bioavailable Pyridoxal 5-Phosphate (P-5-P) form is growing among nutritionists due to its direct usability and lower potential for toxicity at higher doses, making this a good but not optimal choice within the Vitamin B6 category.
Goals
Energy 72.0
Vitamin B6 is a critical coenzyme in metabolic pathways that convert food into cellular energy, supporting the body's overall vitality. This 100mg dose provides ample B6 to facilitate these processes, but a full B-complex might offer more comprehensive energy support due to the synergistic nature of B vitamins.
Brain Health 72.0
B6 is essential for the synthesis of key neurotransmitters like serotonin, dopamine, and GABA, which are vital for cognitive function and nerve communication. While effective, the Pyridoxine HCl form requires conversion in the liver, which can be less efficient for some, potentially impacting its direct brain benefits compared to the active P-5-P form.
Mood Support 72.0
By facilitating the production of mood-regulating neurotransmitters, B6 can significantly contribute to emotional balance and well-being. The 100mg dosage is substantial for aiding these biochemical pathways, although individual responses can vary depending on underlying deficiencies and metabolism.
Recommended Alternatives
95 Value 
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Provides a combination of Pyridoxine HCl and the active P-5-P form at a lower price per serving, offering better B6 quality for the cost.
88 Value 
B-50
NOW
4.7
★★★★★
(30076 ratings)
Offers a comprehensive B-complex, providing a broader range of B vitamins for general health at a very competitive price point.
93 Value 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
Offers the active P-5-P form of B6 at a more moderate price per serving, providing superior bioavailability for improved value.
100 Performance 
Pyridoxal 5'-Phosphate
Thorne
4.8
★★★★★
(1172 ratings)
Utilizes the active P-5-P form of B6, which is more readily used by the body, offering superior bioavailability compared to Pyridoxine HCl.
98 Performance 
P-5-P/Mag
Terry Naturally
4.8
★★★★★
(2668 ratings)
Combines the active P-5-P B6 with beneficial magnesium and zinc, providing a more comprehensive approach to brain and mood support.
87 Performance 
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
A full B-complex, offering synergistic support from all B vitamins for more comprehensive energy, brain, and general health benefits.
65 Budget 
B-6 100 mg
21st Century
4.7
★★★★★
(5959 ratings)
Offers the same dose of Pyridoxine HCl at a significantly lower price per serving.
68 Budget 
B-6 100 mg
NOW
4.8
★★★★★
(6041 ratings)
A more cost-effective option for 100mg of standard B6 from a reputable brand.
70 Budget 
Vitamin B6 100 mg
Solgar
4.8
★★★★★
(2906 ratings)
Same brand and dose but with a lower price per serving, offering better direct value for a similar product.
95 Value
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Provides a combination of Pyridoxine HCl and the active P-5-P form at a lower price per serving, offering better B6 quality for the cost.
88 Value
B-50
NOW
4.7
★★★★★
(30076 ratings)
Offers a comprehensive B-complex, providing a broader range of B vitamins for general health at a very competitive price point.
93 Value
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
Offers the active P-5-P form of B6 at a more moderate price per serving, providing superior bioavailability for improved value.
100 Performance
Pyridoxal 5'-Phosphate
Thorne
4.8
★★★★★
(1172 ratings)
Utilizes the active P-5-P form of B6, which is more readily used by the body, offering superior bioavailability compared to Pyridoxine HCl.
98 Performance
P-5-P/Mag
Terry Naturally
4.8
★★★★★
(2668 ratings)
Combines the active P-5-P B6 with beneficial magnesium and zinc, providing a more comprehensive approach to brain and mood support.
87 Performance
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
A full B-complex, offering synergistic support from all B vitamins for more comprehensive energy, brain, and general health benefits.