Glycine 500 mg
Solgar
Glycine 500 mg
4.8
★ ★ ★ ★ ★
(2669 ratings)
Glycine 500 mg
Score 75.0
A reliable, pure glycine supplement from a trusted brand, though higher doses are often needed for noticeable effects on sleep and stress.
Quantity: 100 Capsule(s)Servings size: 1 Vegetable Capsule(s) (100 servings)
Selected goals:
Other goals:
Brain Health
Stress Relief
Digestive Health
Sleep Support
leaderboard Score 75.0
A reliable, pure glycine supplement from a trusted brand, though higher doses are often needed for noticeable effects on sleep and stress.
insights Analysis
This Solgar Glycine product provides a straightforward 500mg of glycine per capsule, a common dosage for individuals looking to supplement this amino acid for various health goals. Solgar is a highly respected brand known for its quality and purity. However, for significant therapeutic effects, especially for sleep or stress relief, doses of 3-5 grams or more are often recommended by nutritionists and seen in clinical studies, meaning multiple capsules would be consumed daily. While the price per serving seems reasonable for a single capsule, the cost can quickly add up for higher daily intake compared to higher-dose glycine products or bulk powders. Online reviews generally praise Solgar's reliability, though some users note the need to take several capsules.
- From a highly reputable and trusted brand (Solgar).
- Pure glycine formulation without unnecessary additives.
- Convenient capsule form for easy dosing.
- 500mg per capsule is a relatively low dose for common therapeutic applications, requiring multiple capsules.
- Price per serving can become less economical when taking higher recommended doses.
- Does not include synergistic co-factors that might enhance benefits for specific goals.
- Individuals taking medications should consult a healthcare professional before use, especially those affecting brain chemistry or blood sugar.
- Glycine can interact with certain psychiatric medications, so medical advice is crucial.
- Pregnant or nursing women and individuals with pre-existing medical conditions should consult a doctor prior to use.
$10.42($0.10 per serving)
 iHerb | $ 10.42 | |
 Vitacost | $ 10.99 | |
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 Amazon | $ 14.45 |
bolt Effectiveness for goals
Studies suggest glycine supplementation before bedtime may improve subjective sleep quality, reduce daytime sleepiness, and help with sleep onset. It is thought to work by influencing body temperature and certain neurotransmitters.
Glycine may help improve sleep quality by signaling to the brain that it's time to sleep and lowering core body temperature. Some research suggests it can decrease the time it takes to fall asleep and enhance sleep efficiency. It achieves these effects without causing daytime grogginess.
Glycine is involved in the synthesis of creatine, which provides energy to muscle cells, and glutathione, a powerful antioxidant important for muscle recovery. It also supports overall protein synthesis, essential for muscle maintenance and growth. These roles make it valuable for athletic performance and post-exercise recovery.
Glycine acts as an inhibitory neurotransmitter and plays a role in various brain functions. Studies indicate it may support memory and attention, particularly in situations of sleep deprivation. It contributes to overall neural health.
Research indicates that glycine may enhance aspects of cognitive performance, particularly memory and attention, especially in individuals experiencing sleep deprivation. Its role as a neuromodulator contributes to these potential effects.
schedule Dosage, timing & forms
Typical dosages for Glycine can range from 3 to 5 grams per day, though some studies have explored higher amounts for specific purposes. It's often divided into multiple doses throughout the day. Individual needs and the reason for supplementation can influence the appropriate dosage.
Typical daily dosages for Glycine supplements can range from 3 to 15 grams per day, depending on the individual's goals. It is often divided into multiple smaller doses throughout the day. It's advisable to start with a lower dose and adjust as needed.
Glycine can be taken at various times depending on individual goals. For sleep support, it is often recommended to take it about 30 minutes to an hour before bedtime. For general wellness or other benefits, it can be taken with meals or between them.
For those using Glycine to support sleep, it is commonly recommended to take it approximately 30 minutes to an hour before bedtime. This timing allows the body to process it before sleep commences. It can be taken with or without food.
Glycine supplements are most commonly available as a free-form powder, which can be easily mixed into liquids. It is also available in capsule or tablet forms for convenience. The powder form often allows for more flexible dosing.
health_and_safety Safety & interactions
Glycine is generally considered safe when taken at commonly recommended supplement dosages. It is a non-essential amino acid naturally present in the human body and in many foods. Adverse effects are rare and typically mild.
Glycine is an amino acid naturally found in many foods and is generally recognized as safe (GRAS) for consumption. It is well-tolerated by most people when taken within recommended supplement dosages. Extensive research supports its safety profile.
Typical supplemental dosages of glycine range from 3 to 15 grams per day, often divided into multiple doses. However, higher doses, such as 30-60 grams, have been used in research settings under supervision. It's best to follow product label instructions or consult a professional.
There is no officially established upper tolerable intake level for glycine from supplements. However, doses above 15-20 grams per day are considered high and should be used with caution or under professional guidance. Always adhere to product recommendations unless advised otherwise by a healthcare professional.
At typical doses, glycine is usually well-tolerated. Some individuals may experience mild gastrointestinal upset, such as stomach discomfort or nausea, particularly with very high doses. Soft stools have also been reported in isolated cases.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Glycine | 500 mg |
Categories
Glycine 75.0
As a pure glycine product, it fulfills its role as a core glycine supplement. Its score is reflective of its purity and brand reputation, though its dosage per capsule is on the lower side compared to some higher-potency alternatives in the glycine category.
Goals
Digestive Health 70.0
Glycine is a vital component of collagen and plays a role in gut barrier integrity, offering foundational support for digestive health. A 500mg dose contributes to this, but individuals seeking targeted digestive repair might consider combining it with other gut-supportive nutrients or higher glycine intake.
Stress Relief 65.0
Glycine's calming neurotransmitter properties can contribute to stress reduction. While 500mg may offer mild support, more substantial stress-relieving effects typically require higher doses, making this a foundational but not intensely potent option for stress relief.
Sleep Support 65.0
Glycine is known for its ability to improve sleep quality by lowering core body temperature and acting as an inhibitory neurotransmitter. While 500mg can provide some initial support, most research-backed benefits for sleep improvements are seen at doses of 3 grams or more, meaning multiple capsules would be needed.
Recommended Alternatives
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Prostate Essentials
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This product is listed at a similar price per serving (11 vs 10 for Solgar), but contains a minimal 25mg of glycine. While not strictly cheaper per serving for glycine, it is one of the lowest-cost products in the alternative list that includes glycine, if broad-spectrum supplements are considered.
95 Value
Glycine 1000 mg
Life Extension
4.8
★★★★★
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Offering 1000mg of glycine per serving for only 12 cents, this product provides double the glycine content of the Solgar product for a marginal increase in price per serving, making it significantly more economical per milligram of glycine.
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80 Value
Advanced Magnesium Complex
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4.8
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(546 ratings)
While more expensive per serving, this complex offers a substantial 1440mg of Glycine as Magnesium Glycinate, plus various forms of magnesium. This provides excellent value for those seeking both high-dose glycine and magnesium benefits for stress and sleep in one product.
95 Performance
Glycine 1000 mg
Life Extension
4.8
★★★★★
(13233 ratings)
This Life Extension product offers twice the amount of glycine per capsule (1000mg) for only a slightly higher price per serving (12 vs 10). This higher potency provides greater convenience and better cost-effectiveness for individuals needing higher daily doses of glycine for their health goals.
90 Performance
Sleep Nighttime Powder
youtheory
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(158 ratings)
For sleep support, this powder delivers a substantial 3000mg of L-Glycine, along with other synergistic ingredients like L-Theanine and Melatonin. This comprehensive blend offers a much more targeted and effective solution for sleep compared to a standalone 500mg glycine capsule, albeit at a higher per-serving cost.
85 Performance
True Calm
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4.6
★★★★★
(4164 ratings)
This alternative offers a blend of calming ingredients, including 200mg of Glycine, GABA, Taurine, and Magnesium, which can provide more comprehensive support for stress relief and brain health than glycine alone. It’s a multi-faceted approach for the stated goals.