UNIQUE E
A.C. Grace Company
UNIQUE E
4.7
★ ★ ★ ★ ★
(1820 ratings)
Vitamin E 400 IU
Score 75.0
A high-quality Vitamin E supplement in its natural D-Alpha-Tocopherol form, recognized for bioavailability and effectiveness, but comes at a premium price.
Quantity: 30 Softgel(s)Servings size: 1 Softgel(s) (30 servings)
Selected goals:
Other goals:
Anti-Aging
Skin Health
Heart Health
Cardiovascular Support
leaderboard Score 75.0
A high-quality Vitamin E supplement in its natural D-Alpha-Tocopherol form, recognized for bioavailability and effectiveness, but comes at a premium price.
insights Analysis
UNIQUE E by A.C. Grace Company stands out due to its use of pure D-Alpha-Tocopherol, the most biologically active form of Vitamin E. This natural form is preferred by nutritionists over synthetic (DL-alpha) variants for its superior absorption and utilization in the body. Online reviews generally praise its effectiveness and quality, reinforcing its reputation. However, a common critique from online sources and competitive analysis points to its relatively high price per serving, especially for the smaller bottle size, which might deter budget-conscious consumers seeking long-term supplementation. Furthermore, while excellent, it focuses solely on alpha-tocopherol, whereas some experts suggest a mixed tocopherol supplement for a broader range of benefits.
- Contains natural D-Alpha-Tocopherol, the most bioavailable form.
- Reputable brand with a strong focus on quality.
- Generally positive online reviews regarding product effectiveness.
- Higher price per serving compared to many alternatives.
- Only provides D-Alpha-Tocopherol, not a full spectrum of tocopherols (alpha, beta, gamma, delta).
- Smaller serving size (30 servings) for the price can be less economical.
$14.43($0.48 per serving)
 iHerb | $ 14.43 | |
 Amazon | $ 47.72 |
bolt Effectiveness for goals
Vitamin E primarily acts as a powerful antioxidant, protecting cells from oxidative damage caused by free radicals. It is also involved in immune function and plays a role in cell signaling and gene expression. This fat-soluble vitamin contributes to maintaining overall cellular health.
Vitamin E, particularly alpha-tocopherol, neutralizes harmful free radicals by donating an electron, preventing them from damaging cell membranes, proteins, and DNA. This protective action helps mitigate oxidative stress throughout the body. Its fat-soluble nature allows it to protect cell membranes.
Vitamin E is a common ingredient in skincare products, with its antioxidant properties potentially helping to protect skin cells from environmental damage. It may contribute to maintaining skin integrity and moisture. However, scientific evidence for significant therapeutic effects from topical or oral supplements alone for specific skin conditions varies.
Vitamin E is known to play a role in supporting the immune system, particularly in older adults, by protecting immune cells from oxidative damage. Adequate intake is important for optimal immune responses and may enhance the body's natural defense mechanisms. Its impact on specific immune conditions continues to be studied.
Observational studies have linked higher Vitamin E intake from food with a lower risk of heart disease. However, large clinical trials evaluating Vitamin E supplements for heart disease prevention have yielded mixed results and generally do not support a protective effect in healthy individuals. Current evidence suggests that obtaining Vitamin E from dietary sources is preferable for cardiovascular benefits.
schedule Dosage, timing & forms
The recommended dietary allowance (RDA) for Vitamin E in adults is 15 mg (or 22.4 IU) of alpha-tocopherol per day. This amount is typically met through diet for healthy individuals. Supplement dosages can vary and should be considered based on individual needs.
Vitamin E exists in eight chemical forms, including alpha-, beta-, gamma-, and delta-tocopherol, and corresponding tocotrienols. Alpha-tocopherol is the only form recognized to meet human requirements and is most commonly found in supplements. Some products may offer mixed tocopherols or include tocotrienols.
Natural Vitamin E is typically labeled as 'd-alpha-tocopherol' and is derived from plant oils. Synthetic Vitamin E is labeled 'dl-alpha-tocopherol' and is produced chemically. Natural Vitamin E is generally considered to be more bioavailable and potent than synthetic forms.
Yes, Vitamin E is a fat-soluble vitamin, meaning its absorption is significantly enhanced when taken with dietary fat. Taking it alongside a meal or snack that contains some fat is recommended. This helps ensure optimal bioavailability.
The tolerable upper intake level (UL) for alpha-tocopherol in adults from supplements and fortified foods is 1,000 mg per day. This translates to approximately 1,500 IU of natural d-alpha-tocopherol or 1,100 IU of synthetic dl-alpha-tocopherol. Consistently exceeding this level may increase the risk of adverse effects.
health_and_safety Safety & interactions
Yes, high doses of Vitamin E can significantly increase the risk of bleeding when taken with anticoagulant medications like warfarin or antiplatelet drugs. This interaction enhances the effects of these medications. Individuals on such medications must consult a healthcare professional before taking Vitamin E.
At typical supplemental doses, Vitamin E is generally well-tolerated. High doses (above 1,000 mg/day) may lead to nausea, diarrhea, stomach cramps, fatigue, and weakness. A more serious risk at very high doses is an increased tendency to bleed.
Both Vitamin E, particularly in high doses, and aspirin can have antiplatelet effects, increasing the risk of bleeding. Taking them together may amplify this risk. Individuals taking aspirin, especially daily low-dose, should consult a healthcare professional.
The Tolerable Upper Intake Level (UL) for alpha-tocopherol in adults is 1,000 mg (1,500 IU) per day from supplements. Consistently exceeding this limit may increase the risk of adverse effects, including hemorrhagic stroke. It is important to adhere to recommended dosages or consult a healthcare provider.
Individuals taking anticoagulant medications, those with a history of hemorrhagic stroke, or people undergoing surgery should use Vitamin E with caution. Pregnant or breastfeeding women and individuals with certain medical conditions should consult a healthcare provider before supplementation.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin E | 400 IU |
Proprietary Blend (Vitamin) | 432 mg |
Categories
Vitamin E 85.0
This product is a dedicated Vitamin E supplement, offering a high-quality, natural D-Alpha-Tocopherol form which is considered superior for absorption and efficacy among single-tocopherol options. It serves its purpose effectively within the Vitamin E collection.
Goals
Skin Health 85.0
As an antioxidant, Vitamin E protects skin cells from damage caused by UV radiation and environmental pollutants, which are major factors in premature skin aging. It also supports skin barrier function and healing processes, contributing to healthier, more resilient skin.
Anti-Aging 80.0
Vitamin E, particularly the natural D-alpha-tocopherol form, is a powerful antioxidant that helps combat oxidative stress, a key contributor to cellular aging. Its ability to neutralize free radicals supports overall cellular health and reduces age-related damage.
Heart Health 75.0
Vitamin E contributes to heart health by reducing oxidative damage to LDL cholesterol, which is a factor in atherosclerosis. It also plays a role in inhibiting excessive platelet aggregation, though this specific form's impact on heart disease prevention is still a subject of ongoing research, especially when consumed as a single tocopherol.
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