Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor

Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor

Jarrow Formulas4.8 (48,192 ratings)
Format:Tablet Quantity: 100 Tablet(s) · 100 servings
Goals

Product analysis

61 out of 100

Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor offers B6, B12 and folate together in one lemon-flavored formula. The folate form is not clearly identified in the ingredient details, which matters when choosing a specific type of folate.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality33

The B6 and B12 forms are named, but their relative quality cannot be judged firmly. The unspecified folate form makes a complete form comparison harder.

Ingredient Transparency88

All three nutrient amounts are disclosed, making serving comparisons straightforward. The folate form remains unclear even though the B6 and B12 forms are named.

Value For Money40

There is not enough information to judge the combination’s value for money. The known nutrient amounts do not establish how its cost compares with alternatives.

Customer Satisfaction96

Customers respond very positively across a very large review pool. That gives a broad satisfaction picture without establishing benefits.

Product Focus75

The small B-vitamin combination appears reasonably aligned with its intended purposes. Its several goals do not make it a sprawling formula.

Format
Tablet
Container
100 Tablet(s)
Per serving
$0.09
Customer rating
4.8 · 48,192 ratings
Report analysis

Goals

Impact
Highest effect
A Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Folate · 680 mcg DFEVitamin B12 · 1000 mcg

Folate, B12 and B6 provide nutrients involved in normal blood formation and one-carbon metabolism. They can help fill dietary gaps, but their normal functions do not establish improved energy or added benefit when intake is adequate. The supplied information does not establish extra benefit from particular forms or from combining these nutrients.

How this product is rated for Everyday Health

Ingredient fit93

Folate, B12 and B6 supply focused nutritional contributions.
Goal fit
Folate, B12 and B6 supply focused nutritional contributions.
Dose adequacy
Folate and B12 reach their comparison ranges; B6 contributes substantially but partially.

Pathways60

Blood formation and one-carbon metabolism receives the strongest saved coverage. Blood formation, with a smaller energy-metabolism contribution describe the breadth of the supplied findings.
Depth
Blood formation and one-carbon metabolism receives the strongest saved coverage.
Breadth
Blood formation, with a smaller energy-metabolism contribution describe the breadth of the supplied findings.

Evidence82

Folate anchors the nutritional evidence; this does not establish added benefit above adequate intake.
Evidence strength
Folate anchors the nutritional evidence; this does not establish added benefit above adequate intake.
Studied preparation
The counted preparations with substantial known amounts are accepted in the saved findings; no form superiority is established.

Formulation logic100

The counted ingredients can contribute independently or have their required partner.
Partner coverage
The counted ingredients can contribute independently or have their required partner.
Conflicts
No configured ingredient conflict was found.
Effective doses
All 3 counted ingredients provide meaningful amount under the saved criteria.
Study evidence
Folate Supportive 80 studies
Hair Health
Impact
High effect
A Ingredient FitF PathwaysB EvidenceA+ Formulation Logic

The B vitamins support normal nutrient metabolism, but their general biological roles do not establish independent hair growth or regrowth.

How this product is rated for Hair Health

Ingredient fit95

The relevant declarations provide relatively focused nutritional coverage for hair, with the amount findings reflecting the individual ingredients.
Goal fit
The relevant ingredients dominate the formula, giving it a focused nutritional connection to hair.
Dose adequacy
The known amounts meet the supplied comparison references, without establishing a proven hair-growth dose.

Pathways0

These ingredients receive no direct coverage of the listed hair processes. Nutrient relevance can still depend on correcting a deficiency.
Depth
No direct hair-related process receives coverage from these ingredients in the supplied findings.
Breadth
No hair-related process reaches substantial coverage.

Evidence78

The strongest evidence contribution and preparation matches describe different aspects of the ingredients; neither guarantees hair improvement.
Evidence strength
Vitamin B12 supplies the strongest evidence contribution, subject to the ingredient’s specific limitations.
Studied preparation
Eligible declarations are recognized as studied forms; this does not establish hair regrowth in people with adequate nutrient intake.

Formulation logic100

The formula has no matched missing partner or listed conflict. The amount findings distinguish meaningful declarations from small or unresolved quantities.
Partner coverage
No required ingredient partner is missing from the supplied findings.
Conflicts
No listed ingredient conflict was matched; this finding does not establish the absence of every possible interaction.
Effective doses
The ingredients counted here clear the minimum comparison amount; that threshold is not a proven effective hair-growth dose.
Study evidence
Folate Mixed 15 studies

Ingredients

IngredientAmount per servingScore
Vitamin B6 (Pyridoxal 5-Phosphate)
1.5 mg
Folate
680 mcg DFE
Vitamin B12 (Methylcobalamin)
1000 mcg 100
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
A serving provides 1,000 mcg of vitamin B12 as methylcobalamin. At the whole-product serving price, that works out to about $0.09 per 1,000 mcg of B12.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The recorded B12 form is methylcobalamin.
Bioactive B12 Form Selection
The recorded B12 form is methylcobalamin.

Dose, Safety & Label Transparency100

The serving amount and B12 form are recorded.
Therapeutic Dosage Level
The recorded amount is 1,000 mcg of B12 per serving.
Label and Form Transparency
The 1,000 mcg serving amount and its methylcobalamin form are recorded.

Value100

At the whole-product serving price, the cost is about $0.09 per 1,000 mcg of B12.
Price per 1,000 mcg B12
The whole-product serving price corresponds to about $0.09 per 1,000 mcg of B12.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsEveryday Health forVitamin B12
  7. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsEveryday Health forVitamin B12
  8. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsEveryday Health forVitamin B12
  9. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsEveryday Health forVitamin B12
  10. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsEveryday Health forVitamin B12
  11. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  12. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  13. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  14. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  15. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  16. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  17. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  18. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  19. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12