Ionic Selenium 300 mcg

Ionic Selenium 300 mcg

Trace Minerals4.8 (2,850 ratings)
Format:Liquid Quantity: 2 Fluid Ounce(s) · 48 servings
Goals
$19.99 $0.41 per serving

Product analysis

53 out of 100

Ionic Selenium 300 mcg supplies selenium for normal antioxidant and immune functions, with benefits mainly relevant when intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality26

Selenium uses sodium selenate, which has less favorable form characteristics in the comparison. The trace-mineral blend also leaves some component details unclear.

Ingredient Transparency73

The main mineral amounts and most forms are stated. The added blend omits its individual component details and proportions.

Value For Money57

Selenium offers moderate value for the amount supplied. The serving also compares favorably on cost for chloride, while the magnesium value remains uncertain.

Customer Satisfaction88

Customer ratings are strongly positive across thousands of reviews. The broad satisfaction picture does not establish extra health benefits.

Product Focus40

Selenium gives the formula a clear nutritional purpose. Additional benefit is mainly relevant when intake is low, and a large serving does not establish greater usefulness.

Format
Liquid
Container
2 Fluid Ounce(s)
Per serving
$0.41
Customer rating
4.8 · 2,850 ratings
Report analysis

Goals

Immunity
Impact
Highest effect
B+ Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 20 mgSelenium · 300 mcg

Selenium supports normal immune nutrition, with additional benefit mainly relevant when intake is low. The 300 mcg of selenium per serving exceeds the comparison range; retained credit establishes neither extra benefit nor suitability at this exposure.

How this product is rated for Immunity

Ingredient fit83

Selenium account for the main immune connection. The counted amounts meet the saved comparison range.
Goal fit
Relevant immune nutrients sit within a broader formula, so immunity is only part of its focus.
Dose adequacy
The counted amounts reach the saved comparison range; this does not establish an optimal dose or added benefit at higher intakes.

Pathways53

The strongest saved connection is oxidative and inflammatory balance. Other covered areas follow the supplied nutrient and amount findings.
Depth
The strongest saved connection is oxidative and inflammatory balance, rather than a prediction of resistance to infection.
Breadth
The main covered areas are oxidative and inflammatory balance. These describe the saved findings, not proven combined clinical effects.

Evidence85

Selenium provides the clearest evidence connection. The evidence supports the described roles, without establishing general infection prevention.
Evidence strength
Selenium provides the leading evidence connection here, within the supplied limits on normal nutrition and respiratory outcomes.
Studied preparation
The counted preparations match the saved comparisons; that does not imply superior forms or infection prevention.

Formulation logic100

The counted ingredients have no unmet partner requirement or configured conflict. Their amounts meet the saved minimum comparison.
Partner coverage
The counted ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was identified. This finding does not assess every aspect of suitability.
Effective doses
All counted ingredients meet the saved minimum amount comparison; this is not proof of an effective clinical regimen.
Study evidence
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Everyday Health
Impact
Highest effect
A+ Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Magnesium · 20 mgSelenium · 300 mcg

Selenium supplies a nutrient involved in antioxidant enzyme functions, mainly relevant when intake is low. Most US adults obtain adequate selenium, and these roles do not establish added health benefit in selenium-replete users. The selected serving contains 300 mcg, a high nutritional amount whose retained contribution does not establish greater benefit or suitability. Magnesium is present at a small amount that is not independently counted.

How this product is rated for Everyday Health

Ingredient fit97

The relevant ingredients contribute to normal defence functions. Their main value is nutrient availability when intake is low.
Goal fit
The counted ingredients align with the nutritional roles described here, although the product is also linked to other goals.
Dose adequacy
The counted amounts make substantial nutritional contributions; larger amounts do not establish greater benefit or suitability.

Pathways60

The counted ingredients span normal defence functions. These are contributions to normal nutrient functions rather than proof of broad health improvements.
Depth
The strongest nutritional contribution concerns normal antioxidant and immune functions.
Breadth
The saved findings extend across normal defence functions; this describes nutritional roles rather than proven improvements in all these areas.

Evidence82

Selenium anchors the strongest supported nutritional contribution. The preparation findings do not establish extra benefit from named chemical forms or supplementation above adequate intake.
Evidence strength
Selenium provides the strongest supported contribution among the counted ingredients, primarily as nutrition for low intake rather than demonstrated extra benefit above adequacy.
Studied preparation
The counted preparations meet the saved preparation finding; no superiority of a named form or delivery method is established.

Formulation logic100

The independently counted ingredients satisfy the amount and partner checks, with no evaluated conflict triggered. These findings do not establish synergy or overall suitability.
Partner coverage
The counted nutrients work independently or have their required partner present; this does not establish an added combination benefit.
Conflicts
None of the evaluated ingredient combinations triggered a conflict finding; this does not establish overall suitability.
Effective doses
All independently counted ingredients meet the saved amount check; smaller present ingredients may remain outside this finding.
Study evidence
Magnesium Supportive 114 studies
Selenium Supportive 70 studies

Ingredients

IngredientAmount per servingScore
Magnesium (Ionic Trace Minerals)
20 mg
Selenium (Sodium Selenate)
300 mcg 44
Chloride (Ionic Trace Minerals)
60 mg 41
Ionic Trace Minerals
350 mg
Gluten Free Adults 18–50 Vegan No Allergies Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyB+ Value
The serving provides a relatively small 60 mg of chloride. The specific chloride salt is not identified in the saved facts.
How this ingredient is rated

Active Ingredient Quality & Bioavailability20

The specific chloride salt is not identified in the saved facts.
Chloride source quality
The specific chloride salt is not identified in the saved facts.

Dose, Safety & Label Transparency42

The serving contains 60 mg of chloride; its specific salt source is not identified in the saved facts.
Chloride amount per serving
The serving provides a relatively small 60 mg of chloride.
Amount and source disclosure
The saved facts record 60 mg of chloride per serving, but do not identify its specific salt source.

Value80

The whole-product serving costs about $0.42 and provides 60 mg of chloride.
Price per serving
The whole-product serving costs about $0.42 and provides 60 mg of chloride.
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyC Value
Each serving provides 300 mcg of selenium as sodium selenate, leaving a narrower margin for selenium from other sources. The whole-product cost works out to about $0.28 per 200 mcg of selenium.
How this ingredient is rated

Active Ingredient Quality & Bioavailability32

Selenium comes from sodium selenate, an identified inorganic form.
Selenium Chemical Form
Sodium selenate is an inorganic selenium form that the evaluation considers less retained than organic forms.
Form Transparency & Isomer Specificity
The selenium compound is identified as sodium selenate.

Dose, Safety & Label Transparency48

Each serving supplies 300 mcg, leaving a narrower margin for selenium from other sources in the evaluation.
Dosage Efficacy Sweet Spot
The 300 mcg serving is a relatively high amount; selenium from other sources also contributes to total intake.
Safety Margin & UL Adherence
At 300 mcg per serving, the evaluation flags a narrower margin for selenium from food and other supplements.

Value60

The whole-product cost works out to about $0.28 per 200 mcg of selenium.
Price per 200 mcg Serving
At the whole-product price, the equivalent of 200 mcg of selenium costs about $0.28.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium
  2. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsEveryday Health forMagnesium
  3. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsEveryday Health forMagnesium
  4. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsEveryday Health forMagnesium
  5. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsEveryday Health forMagnesium
  6. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledEveryday Health forSelenium
  7. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledEveryday Health forSelenium
  8. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledEveryday Health forSelenium
  9. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsEveryday Health forSelenium
  10. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledEveryday Health forSelenium
  11. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  12. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A · Frontiers in nutrition · 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  13. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ · Science (New York, N.Y.) · 2013
    Single-arm trialImmunity forMagnesium
  14. Effect of magnesium on granulocyte function and on the exercise induced inflammatory response.
    Mooren FC; Golf SW; Völker K · Magnesium research · 2003
    Randomized trialImmunity forMagnesium
  15. Maternal and neonatal outcomes following magnesium sulfate in the setting of chorioamnionitis: a meta-analysis.
    Pergialiotis V; Sapantzoglou I; Rodolaki K; Varthaliti A; Theodora M; Antsaklis P; Thomakos N; Stavros S; Daskalakis G; Papapanagiotou A · Archives of gynecology and obstetrics · 2024
    Meta-analysis6,559 participants8 studies pooledImmunity forMagnesium
  16. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  17. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  18. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  19. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  20. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium